Sepsis is the body’s extreme response to an infection. It occurs when a pre-existing infection triggers a chain reaction throughout a person's body. Sepsis can be difficult to diagnose because patients present different symptoms, and their observation can be subjective. According to the Global Sepsis Alliance, the disease contributes to approximately one in five deaths worldwide, and in the United States alone, it stands as the leading cause of death in hospitals, leading to one in three hospital fatalities. Compounding these mortality rates is a rise in antibiotic and antimicrobial resistance due to overuse or misuse.