Population aging has transformed many aspects of society throughout our world. Senior citizens are increasingly acknowledged as important contributors to the community, and developments in social infrastructure facilitate their continued engagement. In addition, their improved levels of activity, productivity, and socioeconomic status affect society and healthcare demands in unexpected ways.
Objective evidence from nuclear medicine
Evaluating blood flow
Molecular imaging for amyloid scans
It is very difficult to diagnose Alzheimer’s disease at the very early phase, or at the preclinical stage without cognitive impairment, when the patient’s cognition and structural MR shows a normal pattern.
Hiroshi Matsuda, MD, PhD, director of the Cyclotron and Drug Discovery Research Center, Southern Tohoku Research Institute for Neuroscience
Just the beginning
SPECT exams should be made more accessible by reducing costs. It would be useful for screening patients with cognitive risks, to protect both themselves and a healthy society.
Jun Hatazawa, MD, PhD, chief executive director, Japan Radioisotope Association
The statement by Siemens Healthineers customers described herein are based on results that were achieved in the customer’s unique setting. Since there is no “typical” hospital and many variables exist (e.g., hospital size, case mix, level of IT adoption) there can be no guarantee that other customers will achieve the same results.
 Lees AJ, Hardy J, Revesz T. Parkinson’s disease. Lancet. 2009;373(9680):2055–66.
 Booij J, Tissingh G, Boer GJ, Speelman JD, Stoof JC, Janssen AG, et al. [123I]FP-CIT SPECT shows a pronounced decline of striatal dopamine transporter labelling in early and advanced Parkinson’s disease. J Neurol Neurosurg Psychiatry. 1997;62(2):133–40.
 Matsuda H, Murata M, Mukai Y, Sako K, Ono H, Toyama H, et al. Japanese multicenter database of healthy controls for [123I]FP-CIT SPECT. Eur J Nucl Med Mol Imaging. 2018;45(8):1405–1416.
 Catafau AM. Brain SPECT in clinical practice. Part I: perfusion. J Nucl Med. 2001;42(2):259–271.
 Suppiah S, Didier M-A, Vinjamuri S. The Who, When, Why, and How of PET Amyloid Imaging in Management of Alzheimer’s Disease—Review of Literature and Interesting Images. Diagnostics (Basel). 2019;9(2);65.
 Yamane T, Ishii K, Sakata M, Ikari Y, Nishio T, Ishii K, et al. Inter-rater variability of visual interpretation and comparison with quantitative evaluation of 11C-PiB PET amyloid images of the Japanese Alzheimer’s Disease Neuroimaging Initiative (J-ADNI) multicenter study. Eur J Nucl Med Mol Imaging. 2017;44(5):850-857. Epub 2016 Dec 13.
 Matsuda H, Ito K, Ishii K, et al. Quantitative Evaluation of 18F-Flutemetamol PET in Patients with Cognitive Impairment and Suspected Alzheimer’s Disease: A Multicenter Study. Front Neurol. 2021;11:578753.