Women's health

Tomosynthesis and Contrast-Enhanced Mammography Improve Cancer Detection

4 min
Martin Lindner
Published on May 30, 2018
In recent years, a range of advancements in digital mammography have helped to greatly improve breast cancer detection.
Especially in very dense areas of the breast, in which foci of cancer often remain masked by surrounding tissue, suspicious masses can be better detected by a wide-angle system, according to Fisher and Zhao.

Invasive lobular carcinoma grade 2: In 15° Tomo finding is inconclusive while the 50° Tomo shows the finding definitively.  (Courtesy of Wayne Lemish, MD, MIA Radiology, East Melbourne, Australia)

An alternative to FFDM is a “synthetic” mammogram reconstructed from tomosynthesis data, explained Paola Clauser from the Medical University of Vienna, Austria.
ILC 1.8 cm with DCIS G2 10 cm: FFDM, DBT and synthetic mammogramm
(Courtesy of Prof. Th. Helbich, MD, Maria Bernathova, MD, Paula Clauser, MD, University Hospital Vienna, Austria)
The use of mammographhy for functional imaging is emerging as a new paradigm.

71-year-old lady with a palpable lump (left breast): Mammogram shows an irregular mass, margins are not clearly seen; the size of the cancer is difficult to assess. TiCEM shows the real size of this 30 mm invasive lobular carcinoma.[5]


By Martin Lindner

Martin Lindneris is an award-winning science writer based in Berlin, Germany. After completing his medical studies and a doctoral thesis in the history of medicine, he went into journalism. His articles have appeared in many major German and Swiss newspapers and magazines.