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    3. Tomosynthesis and Contrast-Enhanced Mammography Improve Cancer Detection
    Women's health

    Tomosynthesis and Contrast-Enhanced Mammography Improve Cancer Detection

    4min
    Martin Lindner
    Published on May 30, 2018
    In recent years, a range of advancements in digital mammography have helped to greatly improve breast cancer detection.

    A new standard in breast cancer detection

    Especially in very dense areas of the breast, in which foci of cancer often remain masked by surrounding tissue, suspicious masses can be better detected by a wide-angle system, according to Fisher and Zhao.

    Optimizing image acquisition and reconstruction strategies

    Invasive lobular carcinoma grade 2: In 15° Tomo finding is inconclusive while the 50° Tomo shows the finding definitively.  (Courtesy of Wayne Lemish, MD, MIA Radiology, East Melbourne, Australia)

    An alternative to FFDM is a “synthetic” mammogram reconstructed from tomosynthesis data, explained Paola Clauser from the Medical University of Vienna, Austria.
    ILC 1.8 cm with DCIS G2 10 cm: FFDM, DBT and synthetic mammogramm
    (Courtesy of Prof. Th. Helbich, MD, Maria Bernathova, MD, Paula Clauser, MD, University Hospital Vienna, Austria)
    The use of mammographhy for functional imaging is emerging as a new paradigm.

    Towards functional diagnostics in mammography

    71-year-old lady with a palpable lump (left breast): Mammogram shows an irregular mass, margins are not clearly seen; the size of the cancer is difficult to assess. TiCEM shows the real size of this 30 mm invasive lobular carcinoma.[5]

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    By Martin Lindner

    Martin Lindneris is an award-winning science writer based in Berlin, Germany. After completing his medical studies and a doctoral thesis in the history of medicine, he went into journalism. His articles have appeared in many major German and Swiss newspapers and magazines.

    1. Lång K, Andersson I, Rosso A, et al (2016) Performance of one-view breast tomosynthesis as a stand-alone breast cancer screening modality: results from the Malmö Breast Tomosynthesis Screening Trial, a population-based study. Eur Radiol 26:184-90

    2. Goodsitt MM, Chan HP, Schmitz A, et al. (2014) Digital breast tomosynthesis: studies of the effects of acquisition geometry on contrast-to-noise ratio and observer preference of low-contrast objects in breast phantom images. Phys Med Biol 59:5883-902

    3. Schneider BP, Miller KD (2005) Angiogenesis of breast cancer. J Clin Oncol 23:1782-90

    4. Kariyappa KD, Gnanaprakasam F, Anand S, et al. (2016) Contrast enhanced dual energy spectral mammogram, an emerging addendum in breast imaging. Br J Radiol 89:20150609

    5. Courtesy of Prof. Luis Pina, MD, University of Navarra, Pamplona, Spain

    6. This product is under development and not commercially available. Its future availability cannot be ensured.

    1. The statements by Siemens Healthineers customers described herein are based on results that were achieved in the customer’s unique setting. Since there is no “typical” hospital and many variables exist (e.g., hospital size, case mix, level of IT adoption) there can be no guarantee that other customers will achieve the same results.

    2. Results from case studies are not predictive of results in other cases. Results in other cases may vary.