“AI has to inspire trust.”

Machine learning allows the computer to learn from examples and apply the extracted concepts to new data.

Published on September 3, 2020

Artificial intelligence is the key technology of the future. Tobias Heimann, PhD, of Siemens Healthineers believes that this is especially true for the healthcare sector – yet he is also well aware of the technology’s inherent challenges.

<p><b><br></b></p><p>Text: Rebecca Murr and Doris Pischitz<br>Photos: Bernward Bodenstedt<br><br><b>Tobias Heimann, why are so many people afraid of artificial intelligence (AI) in healthcare?</b><br>I think the uncertainty stems from the fact that we are currently hearing and reading a great deal about AI. “Artificial intelligence” is also not a protected term. Reports about AI can be talking about completely different things. There are countless movies about artificial intelligence going crazy and wanting to destroy the human race. Thankfully, that’s not what we mean when we talk about AI.<br><br><b>And what exactly does artificial intelligence mean for Siemens Healthineers?</b><br>For us, it’s about a specialized form of artificial intelligence known as weak AI, which is based on machine learning technology. This means that you have a specific task and can use examples to train the computer to perform that task. The computer analyses the examples and produces a model that allows it to process similar data in the same way in future. A great deal has happened in this field over recent years, especially in computer vision. Self-driving cars are one example.<br><br><b>What are the specific concerns about AI in the healthcare sector?</b><br>In medicine, we are currently dealing with two main groups: radiologists and patients. Concerns that diagnostic computer algorithms might soon replace radiologists have largely subsided, and a more realistic perspective is gaining ground. AI could prove to be an indispensable aid for coping with increasing workloads, and a promising research tool. Using extensive image datasets, for instance, intelligent algorithms could potentially enable noninvasive tumor profiling to predict the course of disease or treatment response.<br><br>Patients are reluctant to embrace healthcare provided by AI, even when it outperforms human doctors. This is because they believe their medical needs are unique and cannot be adequately addressed by what they see as inflexible and standardized algorithms. However, patients are comfortable with medical AI if a physician remains in charge of the ultimate decision.[1] For us, this means that we have to make AI a very personal experience for patients, and one that inspires trust. This can only work in collaboration with the physician.</p>

Tobias Heimann, PhD, Siemens Healthineers

<p><b>What do you consider to be the real risks of artificial intelligence?<br></b>I can understand why people are scared of strong AI, the one from the movies. I don’t feel that it’s a threat, however, because so much more would have to happen before a system became a danger to humanity. Of course, weak AI also poses risks – those lie in the possibility of errors. No system is perfect. If a system is good, it will provide the right answer in perhaps 99 percent of cases.<br>Another point concerns the ability to trace the computer’s decision. This is not just a problem in medicine; it applies in every setting where decision-making systems are used. A few studies have investigated how systems can explain themselves. We also want our systems to be able to assess themselves and show how reliable the result is. Especially in medicine, where we have a large number of special cases, it’s important to have software that can say: “Okay, I’ve never seen a case like this patient before.” With that in mind, we optimize our AI systems for safety and reliability, and for cognitive effort when it comes to understanding how the AI arrives at its results.[2]<br><br><b>What qualifies a medical technology manufacturer to become involved in AI?<br></b>We have been involved in machine learning since the 1990s and already have 45 AI-based products on the market. As a medical technology manufacturer, we have in-depth expertise in departmental and clinical workflows, and we possess medical knowledge linking our imaging and laboratory technology. In addition, we can rely on long-standing close collaborations with leading healthcare facilities around the world. They support our research with anonymized data and are also keen to help us develop and test our AI-based products – because they already see the advantages that AI brings to their daily routine. We only launch new solutions once we have tested them very, very carefully, and in collaboration with customers as part of scientific studies and publications.<br><br><b>How exactly do these AI systems learn?<br></b>We have over a billion anonymized clinical images, findings, and reports from different body regions and imaging modalities. That’s millions of images, plus metainformation such as examination date or acquisition parameters. This also includes information about where the data come from, who the contact person is, and how they can be used and for what purpose. As an example, we’ve used our AI-Rad Companion Chest CT1 to examine thorax CT scans. This required thousands of thorax CT images from different patients who had been treated in different hospitals around the world. We acquired these from our customer network and from certified brokers. Experienced clinical radiologists and technicians annotated them by hand. This means that multiple experts – from our clinical collaboration partners as well as our own employees – used the mouse to click on the images and define, for instance, what pulmonary emphysema or a lung nodule look like. The computer can then learn from these examples and apply the extracted concepts to new data. The quality of these annotations and data has a major impact on the quality of the final product.<br><br><b>Your AI systems must require an enormous amount of computing power. How are you dealing with this?<br></b>We have built our own supercomputing infrastructure, based on NVIDIA GPUs, to develop our AI software. Our Sherlock AI supercomputer provides 24 petaflops of performance and runs over 600 deep-learning experiments daily.<br><br><b>What are the greatest challenges facing AI in healthcare?<br></b>We have already discussed one challenge – the initial skepticism from physicians and patients. Another problem is that the medical technology market as a whole is already very strictly regulated. And in addition to complying with existing legislation, manufacturers and hospitals must now also find joint, adequate responses to rules governing privacy and cybersecurity. However, I personally think the main problem is that data in the healthcare system are scattered across so many different locations and systems. Connecting them requires an enormous amount of technical effort. Initial standards for this are being developed, and hopefully they will be increasingly used and help to simplify the process.</p>
AI in medicine supports system operation, diagnosis and treatment, patient prognosis and in the future even population health management.
<p><b>How does Siemens Healthineers envision using artificial intelligence in medical technology and healthcare provision? </b><br>Today, we are capable of building systems that perform image recognition and analysis much better than was thought possible just ten years ago. This doesn’t mean that we’ve solved all the problems, though. There is still an enormous amount of work to be done. With regard to automated image recognition and analysis, we expect to see an increasing number of products being deployed in daily clinical practice – systems that simply run in the background and check certain things as standard, so as to guarantee a certain level of quality. The next step is decision support. This involves looking at the patient as a whole, and all the associated data – whether clinical, genetic, or molecular. All knowledge about the patient should be collected and analyzed to allow predictions about how the patient will develop or how a certain therapy might work. This field also includes Digital Twin technology. The next step focuses on entire patient cohorts, such as all the patients in a hospital or department, and later perhaps also all the patients in a region or state.<br>AI is therefore a technology that can be used effectively at many different levels in healthcare. It is also a topic that will be with us for some time to come. We are just at the very beginning of an ongoing development.</p>
<p><b>Rebecca Murr</b> is an editor of the employee magazine of Siemens Healthineers. Doris Pischitz is an editor on the News &amp; Stories team at Siemens Healthineers. Her main areas of focus are innovations and IT.</p>