Neurology: “We have a life together with these patients”
There is no single method for imaging neurological diseases. However, the advent of 7 tesla (7T) magnetic resonance imaging has been a game changer for many patients.
Published on March 27, 2023
Perspectives spoke with Professor Maxime Guye, MD, PhD, who is deputy director of the Centre for Magnetic Resonance in Biology and Medicine (CRMBM) at Aix-Marseille University (AMU) and director of the medical site of CRMBM at the Timone University Hospital in Marseille, France.
Since when have you been using 7 tesla (7T) research MRI and what are your research areas?
Could you please relate one or two patient cases where 7T research MRI has been particularly helpful?
You mentioned epilepsy, which is also your area of expertise. How does epilepsy impact the lives of your patients?
What role does MRI play in the diagnosis and treatment of these patients today?
How important is scanning speed in your research?
How would multinuclear MR and the ability to image e.g., sodium, support neurological diagnoses?
How does 7T MRI perform in standard (non-neurological) examinations? What would be your hopes for a next-generation 7T system in this field?
How important will 7T MRI be in the future? Does it have a future in broad clinical application?
What continues to drive you as a physician and as a researcher?
 Rotta J, Perosa V, Yakupov R, Kuijf HJ, Schreiber F, Dobisch L, et al. Detection of Cerebral Microbleeds With Venous Connection at 7-Tesla MRI. Neurology. 202196(16):e2048–e2057.
 Ni J, Auriel E, Martinez-Ramirez S, Keil B, Reed AK, Fotiadis P, et al. Cortical localization of microbleeds in cerebral amyloid angiopathy: an ultra high-field 7T MRI study. J Alzheimers Dis. 2015;43(4):1325–30.
 Song JW, Moon BF, Burke MP, Kamesh Iyer S, Elliott MA, et al. MR Intracranial Vessel Wall Imaging: A Systematic Review. J Neuroimaging. 2020;30(4):428–442.
 Yao A, Rutland JW, Verma G, Banihashemi A, Padormo F, Tsankova NM, et al. Pituitary adenoma consistency: direct correlation of ultrahigh field 7T MRI with histopathological analysis. Eur J Radiol. 2020;126:108931.
 Rutland JW, Delman BN, Gill CM, Zhu C, Shrivastava RK, Balchandani P. Emerging Use of Ultra-High-Field 7T MRI in the Study of Intracranial Vascularity: State of the Field and Future Directions. AJNR Am J Neuroradiol. 2020;41(1):2–9.
 Bian W, Hess CP, Chang SM, Nelson SJ, Lupo JM. Susceptibility-weighted MR imaging of radiation therapy-induced cerebral microbleeds in patients with glioma: a comparison between 3T and 7T. Neuroradiology. 2014;56(2):91–6.
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