Inflammation & Infection Test Solutions
Siemens Healthineers offers test solutions to monitor inflammation, infection, and sepsis to improve outcomes through early diagnosis.

Inflammation is a vital part of the body’s immune response. The function of inflammation is to destroy and remove pathogens. If destruction is not possible, inflammation limits effects by confining the pathogen and its products. It is also important for repairing and replacing tissue damaged by the pathogen and its products. Inflammation can potentially be a harmful process. Components of inflammation that are capable of destroying microbes can also injure bystander normal tissue. There are two types of inflammation, acute and chronic.1


Acute vs. Chronic Inflammation

FeatureAcuteChronic
OnsetFast: minutes or hoursSlow: days
Cellular infiltrateMainly neutrophilsMonocytes/macrophages and lymphocytes
Tissue injury, fibrosisUsually mild and self-limitedOften severe and progressive
Local and systemic signsProminentLess prominent; may be subtle

 


Learn More about Inflammation

Inflammatory responses are essential for the maintenance of normal tissue homeostasis. The molecular mechanism of inflammation is quite a complicated process which is initiated by the recognition of specific molecular patterns associated with either infection or tissue injury.2

The importance of inflammation is that it can sometimes be inappropriately triggered or poorly controlled, and is thus the cause of tissue injury in many disorders.3 Many diseases are associated with inflammation, such as sepsis, neoplastic disorders, autoimmune diseases, AIDS, alcoholic liver disease, and infections, or transplant rejection.

Causes of Inflammation

  • Infections (viral, bacterial, parasitic)
  • Trauma (blunt, penetrating)
  • Tissue necrosis
  • Foreign bodies
  • Immune reactions (hypersensitivity)

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1http://www.hopkinsmedicine.org/mcp/education/300.713%20lectures/300.713%202013/beck_08.26.2013.pdf

2Ahmed, A.U. Front. Biol. (2011) 6: 274. doi:10.1007/s11515-011-1123-9

3https://www.slideshare.net/drmohammadmanzoor/inflammation-overview