Integri-sense Technology

Integri-sense™ Technology is the guardian of patient results. The system performs frequent quality and sample integrity checks before, during, and after every patient sample. Automatic quality control, comprehensive calibrations, and advanced software algorithms combine to enable the analyzer to be ready to generate reliable, clinically actionable results each and every time, delivering confidence with every result.


Automatic quality control

The AQC cartridge enforces specific levels of external QC at specified time intervals and is fully programmable as requirements mandate. Three truly independent levels of QC materials span the clinically significant ranges.

  • Measurement of control analytes confirms that acceptable patient test results are reported.
  • QC materials and patient samples follow exactly the same pathway in the measurement cartridge.
  • The same expected analyte ranges apply across every test setting. Fixed or absolute QC limits are designed to be consistent with the medical needs of clinicians, minimizing false rejections caused by erroneous QC signals.
  • The RAPIDPoint® 500e Blood Gas System complies with CLIA, CLSI guidelines, and ISO 15189, with onboard review of Levey-Jennings charts.

Month-on-month and year-on-year results are always comparable.


Automatic system calibration

Routine calibrations at set intervals adjust the slope and offset drift for each analytical parameter without operator involvement.

  • Full auto-calibration includes measurement of zero and slope for total hemoglobin.
  • Prevent erroneous results by turning off an individual parameter in the event of an unsuccessful calibration.
  • Calibration can be temporarily deferred to allow a STAT sample to run.
  • Retrospective calibration (Retrocal) auto-commences when a measurement cartridge initializes or when excessive drift is detected in sensors.
  • Retrocal minimizes potential effects of interfering substances such as benzalkonium chloride on sensors. If this interferent is detected, the system will present a real-time warning flag to notify the operator and recommend caution when interpreting sodium results.

Analyzers perform and report within specifications.


Advanced sample management

The universal sample port enables analyzer operation to be biohazard protected and the results independent of operator technique.

  • The system employs a standardized sampling procedure using both syringes and capillaries, with no sample adapters needed.
  • The fast sample port replacement occurs in approximately 90 seconds.
  • Automatic, hands-free sample aspiration and advanced clot management and clearance facilitate ease of use.

Sample port facilitates consistently accurate results with a minimum of downtime.


Comprehensive CO-oximetry

Precise optical measurement and reporting of sample hemoglobin moieties and oxygen saturation provide clinicians with vital diagnostic information.

Sample hemolysis is not required. Absorbance measurement at multiple wavelengths across a short optical path generates a precise spectral blueprint. The analyzer automatically detects and corrects for deviations caused by common interferences. Algorithms auto-correct for light scatter from erythrocyte membranes. The analyzer reports tHb, sO2, O2Hb, HHb, COHb, MetHb, and neonatal total bilirubin with accuracy equivalent to hemolyzed methods. CO-oximetry supports assessment of a patient’s oxygenation status.

Additional Features

Clot and Bubble Checks

Clot and Bubble Checks

The system continuously monitors patient samples for clots and bubbles and triggers an automatic clot clearance sequence to protect the sensors.
Readiness Checks

Readiness Checks

Deep-system health, calibration, and fluidics checks provide analytical quality before, during, and after sample measurement.
Temperature Checks

Temperature Checks

Three preheaters maintain every sample at 37°C throughout the sample pathway to enable the analysis to be performed at the correct temperature.
Wash Sequence Checks

Wash Sequence Checks

Vigorous wash sequences prevent carryover for accurate patient results and optimal sample throughput.

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