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ADVIA 1800 Chemistry System

Pushing the limit of productivity

The ADVIA® 1800 Clinical Chemistry System pushes the limit of productivity. Its extensive menu allows integration of testing for clinical chemistry, drugs-of-abuse, therapeutic drug monitoring (TDM) and specific proteins like Cystatin C and CardioPhase® hsCRP. The ADVIA 1800 Clinical Chemistry System offers:

  • Throughput of up to 1,800 tests per hour provides speed to keep pace with workload peaks
  • 200 basic metabolic panels per hour to meet turnaround-time demands
  • Large onboard reagent capacity and optional concentrated reagents to reduce interruptions
  • Optimal standardization of reagents and systems for efficient consumable usage
  • Refrigerated onboard storage of controls and reagents for extended stability and increased productivity
  • Automation ready design – no additional hardware required
ADVIA 1800 Chemistry System

ADVIA 1800 Chemistry System

Pushing the limit of productivity

    Features & Benefits

    The ADVIA 1800® Clinical Chemistry System pushes the limit of productivity of the core lab and meets the turnaround-time (TAT) goals of today’s laboratories. Its extensive and growing menu allows integration of general clinical chemistry testing with testing for drugs-of-abuse, therapeutic drug monitoring (TDM), special chemistry and specific proteins like Cystatin C and CardioPhase® hsCRP.

      

      The ADVIA 1800 Clinical Chemistry System is an ideal solution for mid- to high-volume chemistry analysis. Featuring intuitive new software and capabilities, it’s designed to deliver power and speed to meet the most demanding performance needs. The ADVIA 1800 System moves laboratories to smarter chemistry testing.

      Automation ready design

      • Point-in-space aspiration offers connectivity to a track, VersaCell or rack handler without robotics or special hardware
      • Redundant sample loading for built-in backup and easy handling of non-routine samples
      • Direct sampling from track prevents detaining tubes at analyzer and reduces aliquoting

      Peak productivity

      • Throughput of up to 1,800 tests per hour provides the speed to keep pace with workload peaks
      • 200 Basic metabolic panels per hour to meet turnaround-time demands
      • Automatic Sample Retain technology provides the ability to perform reruns and dilutions without the need to retrieve primary tubes
      • Consolidation power with a comprehensive menu, consistent cycle times, speed and open application capability

      Total system reliability

      • Minimal-maintenance ISEs
      • Robust hardware and simplified software design, with automatic calibration validation and tracking
      • Advances in reagent onboard stability, calibration frequency, interference reduction and assay linearity expansion
      • Direct water connection
      • Remote diagnostics and ILQC (Inter-Laboratory Quality Control) options

      Easy efficiency

      • Large onboard reagent capacity and optional concentrated reagents reduce interruptions
      • High-resolution touchscreen delivers push-button operation
      • Reagent pause capability and onboard Sample Pause button make loading easy
      • Minimal maintenance requirements, including no-maintenance oil bath
      • Sample integrity checking, including serum indices reporting, short sample flagging and clot detection, reduces manual intervention

      Assays

      Diabetes
      Fructosamine
      Hemoglobin A1c (Enzymatic)

      Drugs of Abuse/Toxicology
      6-Acetylmorphine (6-AM)*
      Acetaminophen
      Amphetamines
      Barbiturates
      Barbiturates, Serum
      Benzodiazepines
      Benzodiazepines, Serum
      Buprenorphine*
      Cannabinoids (THC)
      Cocaine Metabolite
      Ecstasy
      EDDP††
      Ethyl Alcohol
      Ethyl Glucuronide (EtG)††,§§
      Fentanyl††
      Methadone
      Opiates
      Oxycodone*
      Phencyclidine
      Propoxyphene
      Salicylate
      Tramadol††
      Tricyclic Antidepressants

      General Chemistry
      Alanine Aminotransferase†
      Alanine Aminotransferase (P5P)†
      Albumin (BCG)†,‡
      Albumin (BCP)
      Alkaline Phosphatase
      Ammonia
      Amylase
      Aspartate Aminotransferase†
      Aspartate Aminotransferase (P5P)†
      Bilirubin, Direct
      Bilirubin, Total
      Calcium (Arsenazo)†
      Calcium (CPC)†
      Carbon Dioxide (Enzymatic)
      Chloride
      Cholesterol†
      Cholinesterase
      Creatine Kinase
      Creatinine†
      Creatinine (Enzymatic)
      Gamma-Glutamyltransferase (GGT)
      Glucose (Hexokinase)†
      Glucose (Oxidase)†
      HDL Cholesterol
      Iron
      Lactate
      Lactate Dehydrogenase (L-P)
      Lactate Dehydrogenase (P-L)
      LDL Cholesterol
      Lipase
      Magnesium†
      Microalbumin
      Pancreatic Amylase
      Phosphorus†
      Potassium
      Sodium
      Total Iron Binding Capacity (TIBC)
      Total Protein†
      Total Protein, CSF/Urine
      Triglycerides†
      Urea Nitrogen (BUN)†
      Uric Acid†

      Specific Proteins
      α1-Acid Glycoprotein
      α1-Antitrypsin
      Antistreptolysin O
      Apolipoprotein A1
      Apolipoprotein B
      β-2 Microglobulin
      Complement C3
      Complement C4
      CRP
      CRP, High Sensitivity
      CRP, Wide Range
      Cystatin C
      Ferritin
      Haptoglobin
      Immunoglobulin A
      Immunoglobulin G
      Immunoglobulin M
      Lipoprotein(a)
      Prealbumin
      Rheumatoid Factor
      Soluble Transferrin Receptor (sTfR)§,††
      Transferrin

      Therapeutic Drug Monitoring
      Carbamazepine
      Digoxin
      Gentamicin
      Lamotrigine††
      Levetiracetam††
      Lithium
      Methotrexate**,††
      Phenobarbital
      Phenytoin
      Theophylline
      Tobramycin
      Valproic Acid
      Vancomycin

      Validity Testing
      Creatinine*,§§
      Nitrite*,§§
      Oxidant*,§§
      pH*,§§
      Specific Gravity*,§§

      Technical Specifications

      Overview

      Type of System

      Random, continuous access, batch, discrete processing

      Throughput Rate

      Up to 1800 tests/hour: 1200 tests/hour colorimetric, 600 tests/hour ISE

      Assay Capacity Onboard

      55 including 3 ISE

      Sample Handling

      Sample Tubes

      5 mL, 7 mL, 10 mL tubes, 2 mL sample cups

      Sample Tray

      84 samples, positive sample identification

      Sample Integrity Check

      Qualitative check for hemolysis, lipemia, and icterus

      STAT Sample Loading

      84, not dedicated

      Bar Codes

      Interleaved 2 of 5, Code 39, Code 128, Codabar (NW7)

      Auto-repeat

      Automatic repeat testing from the retained prediluted sample or original sample

      Auto-dilution

      Automatic dilution from retained prediluted sample

      Auto-reflex Testing

      Automatic ability to perform 3 additional tests based on results of first test

      Primary Probe

      Liquid Level Sensing, Crash Protection, Clot/Clog Detection, Short Sample Detection

      Microvolume Technology

      Automatic Sample Predilution

      Samples diluted 1:5 (30 μL sample + 120 μL saline generates up to 15 tests), retained for auto-repeat until results are available

      Predilution Tray

      120 dilution cuvettes

      Original Sample Volume

      2 to 30 μL; average of 2-3 μL per test

      Average Reagent Volume

      80-120 μL per test

      Storage Capacity Onboard

      25,200 tests average; Usage of concentrated reagents increases maximum capacity

      Reaction Area

      Reaction Tray

      221 reusable plastic cuvettes

      Cuvette Optical Path Length

      10 mm

      Reaction Bath

      Inert fluorocarbon oil circulation system, 37°C

      Photometer

      14 fixed wavelengths (340, 410, 451, 478, 505, 545, 571, 596, 658, 694, 751, 805, 845, and 884 nm)

      Light Source

      12 V, 50 W halogen lamp, cooled by forced water circulation

      Assay Methods

      Endpoint, rate reaction, 2-point rate, multipoint homogeneous immunoassay

      Reaction Times

      3, 4, 5, 10, 15, and 21 minutes

      Automatic Correction

      Serum blank, cell blank, measurement point change, sample volume change in reassay

      Point Forwarding

      Automatically extends linearity over assay range samples

      Reagent Handling

      Reagent Tray

      2 trays, 56 positions each, refrigerated

      Reagent Capacity Onboard

      52 colorimetric methods

      Dispensing System

      2 probes with Liquid Level Sensing and Liquid Surface Verification

      Reagent Wedges

      20, 40, 70 mL bar-code-labeled wedges

      Reagent Inventory Management

      Tracks tests remaining, lot number, onboard stability, and expiration date

      Reagent Dilutions

      Capability to dilute concentrated reagents onboard

      Onboard Stability

      Up to 60 days

      Open System Capability

      Channels

      200 channels, includes user-defined applications

      3rd Party Applications

      Varies by country, can be configured on system

      ISE

      ISE

      Indirect simultaneous measurement of Na+, K+, Cl -

      Sample Volume

      22 μL for all three tests

      Priming

      Automatic priming cycle

      Electrode Shelf Life

      30,000 samples or 3 months

      Throughput Rate

      600 tests/hour; 200 tubes/hour

      Calibration/QC

      Calibration Interval

      Up to 60 days, tracked by software

      Auto-calibration/Auto-QC

      User-defined time interval or with new reagent container

      View Calibration/QC Data

      Graphical display of calibration curves and QC; Siemens Remote Service QC monitoring

      Calibration/Control Tray

      61 refrigerated positions for calibrators, controls, and diluents

      Data Management

      Operating Computer

      Windows® XP, 1 GB RAM, touch screen monitor 19”

      System Documentation

      Operator manual and assay sheets online

      Host Interface

      RS 232C bidirectional

      Data Storage

      70,000 patient tests

      Onboard Maintenance Logs

      Schedule and monitor routine maintenance activities via software

      Host Query

      ASCII; system requests work order or batch of work orders from host

      General Specifications

      Power Requirements

      200/220/230/240 V +/– 10%, 20 A, 50/60 Hz, 3 KVA

      Water Requirements

      Deionized water from pressurized water (10-30 psi/169-207 KPa) Average Consumption: 30 liters per hour

      Drain Requirements

      Minimum of 40 liters per hour

      Dimensions

      ADVIA 1800: 44.6 (h) x 58.3 (w) x 34.5 (d) in, 113.3 (h) x 148.0 (w) x 87.6 (d) cm

      Weight

      ADVIA 1800: 1,323 lbs (600 kg)

      Compliance

      UL, cUL, CE

      Noise Specifications

      Open cover less than 70 db

      Average Heat Output

      4,299 BTU/hour @ 50 Hz, 3,023 BTU/hour @ 60 Hz

      Operating Temperature Range

      18°-30°C/64°-86°F

      Ambient Humidity

      40%-70%

      * Alliance Application manufactured and distributed by Siemens Healthcare Diagnostics.

      † Also available in concentrated version.

      ‡ ADVIA Chemistry XPT System supports concentrated version only.

      § Not available for sale in the U.S.

      ** Not currently available on the ADVIA Chemistry XPT System.

      †† Alliance Application manufactured by third party, distributed by Siemens Healthcare Diagnostics.

      ‡‡ In development, future availability cannot be guaranteed.

      §§ Restricted in the U.S. to law enforcement-related use (forensic use only).


      Due to local regulations, not all products are available in all countries.


      The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.