ADVIA 1800 Chemistry System
Pushing the limit of productivity
The ADVIA® 1800 Clinical Chemistry System pushes the limit of productivity. Its extensive menu allows integration of testing for clinical chemistry, drugs-of-abuse, therapeutic drug monitoring (TDM) and specific proteins like Cystatin C and CardioPhase® hsCRP. The ADVIA 1800 Clinical Chemistry System offers:
-
Throughput of up to 1,800 tests per hour provides speed to keep pace with workload peaks
- 200 basic metabolic panels per hour to meet turnaround-time demands
- Large onboard reagent capacity and optional concentrated reagents to reduce interruptions
- Optimal standardization of reagents and systems for efficient consumable usage
- Refrigerated onboard storage of controls and reagents for extended stability and increased productivity
- Automation ready design – no additional hardware required
ADVIA 1800 Chemistry System
Features & Benefits
The ADVIA 1800® Clinical Chemistry System pushes the limit of productivity of the core lab and meets the turnaround-time (TAT) goals of today’s laboratories. Its extensive and growing menu allows integration of general clinical chemistry testing with testing for drugs-of-abuse, therapeutic drug monitoring (TDM), special chemistry and specific proteins like Cystatin C and CardioPhase® hsCRP.
The ADVIA 1800 Clinical Chemistry System is an ideal solution for mid- to high-volume chemistry analysis. Featuring intuitive new software and capabilities, it’s designed to deliver power and speed to meet the most demanding performance needs. The ADVIA 1800 System moves laboratories to smarter chemistry testing.
Automation ready design
- Point-in-space aspiration offers connectivity to a track, VersaCell or rack handler without robotics or special hardware
- Redundant sample loading for built-in backup and easy handling of non-routine samples
- Direct sampling from track prevents detaining tubes at analyzer and reduces aliquoting
Peak productivity
- Throughput of up to 1,800 tests per hour provides the speed to keep pace with workload peaks
- 200 Basic metabolic panels per hour to meet turnaround-time demands
- Automatic Sample Retain technology provides the ability to perform reruns and dilutions without the need to retrieve primary tubes
- Consolidation power with a comprehensive menu, consistent cycle times, speed and open application capability
Total system reliability
- Minimal-maintenance ISEs
- Robust hardware and simplified software design, with automatic calibration validation and tracking
- Advances in reagent onboard stability, calibration frequency, interference reduction and assay linearity expansion
- Direct water connection
- Remote diagnostics and ILQC (Inter-Laboratory Quality Control) options
Easy efficiency
- Large onboard reagent capacity and optional concentrated reagents reduce interruptions
- High-resolution touchscreen delivers push-button operation
- Reagent pause capability and onboard Sample Pause button make loading easy
- Minimal maintenance requirements, including no-maintenance oil bath
- Sample integrity checking, including serum indices reporting, short sample flagging and clot detection, reduces manual intervention
Assays
Diabetes
Fructosamine
Hemoglobin A1c (Enzymatic)
Drugs of Abuse/Toxicology
6-Acetylmorphine (6-AM)*
Acetaminophen
Amphetamines
Barbiturates, Urine
Barbiturates, Serum
Benzodiazepines, Urine
Benzodiazepines, Serum
Buprenorphine*
Cannabinoids (THC)
Cocaine Metabolite
Ecstasy
Ethyl Alcohol
Methadone
Methadone Metabolites
Opiates
Oxycodone*
Phencyclidine
Propoxyphene
Salicylate
Tricyclic Antidepressants
General Chemistry
Alanine Aminotransferase†
Alanine Aminotransferase (P5P)†
Albumin (BCG)†,‡
Albumin (BCP)
Alkaline Phosphatase (AMP)§
Alkaline Phosphatase (DEA)**
Ammonia
Amylase
Aspartate Aminotransferase†
Aspartate Aminotransferase (P5P)†
Bilirubin, Direct
Bilirubin, Total
Calcium (Arsenazo)†
Calcium (CPC)†
Carbon Dioxide (Enzymatic)§
Chloride
Cholesterol†
Cholinesterase
Creatine Kinase
Creatinine†
Creatinine (Enzymatic)
Gamma-Glutamyltransferase (GGT)
Glucose (Hexokinase)†
Glucose (Oxidase)†
HDL Cholesterol
Iron
Lactate
Lactate Dehydrogenase (L-P)
Lactate Dehydrogenase (P-L)
LDL Cholesterol
Lipase
Magnesium†
Microalbumin
Pancreatic Amylase
Phosphorus†
Potassium
Sodium
Total Iron Binding Capacity (TIBC)
Total Protein†
Total Protein, CSF/Urine
Triglycerides†
Urea Nitrogen (BUN)†
Uric Acid†
Specific Proteins
α1-Acid Glycoprotein
α1-Antitrypsin
Antistreptolysin O
Apolipoprotein A1
Apolipoprotein B
β-2 Microglobulin
Complement C3
Complement C4
CRP
CRP, High Sensitivity
CRP, Wide Range
Cystatin C
Ferritin
Haptoglobin
Immunoglobulin A
Immunoglobulin G
Immunoglobulin M
Lipoprotein(a)
Myoglobin
Prealbumin
Rheumatoid Factor
Soluble Transferrin Receptor (sTfR)**,††,‡‡
Transferrin
Therapeutic Drug Monitoring
Carbamazepine
Digoxin
Gentamicin
Lithium
Methotrexate††,‡‡
Phenobarbital
Phenytoin
Theophylline
Tobramycin
Valproic Acid
Vancomycin
Validity Testing
Creatinine††,§§
Nitrite††,§§
Oxidant††,§§
pH††,§§
Specific Gravity††,§§
Technical Specifications
| Overview | |
|---|---|
| Type of System | Random, continuous access, batch, discrete processing |
| Throughput Rate | Up to 1800 tests/hour: 1200 tests/hour colorimetric, 600 tests/hour ISE |
| Assay Capacity Onboard | 55 including 3 ISE |
| Sample Handling | |
|---|---|
| Sample Tubes | 5 mL, 7 mL, 10 mL tubes, 2 mL sample cups |
| Sample Tray | 84 samples, positive sample identification |
| Sample Integrity Check | Qualitative check for hemolysis, lipemia, and icterus |
| STAT Sample Loading | 84, not dedicated |
| Bar Codes | Interleaved 2 of 5, Code 39, Code 128, Codabar (NW7) |
| Auto-repeat | Automatic repeat testing from the retained prediluted sample or original sample |
| Auto-dilution | Automatic dilution from retained prediluted sample |
| Auto-reflex Testing | Automatic ability to perform 3 additional tests based on results of first test |
| Primary Probe | Liquid Level Sensing, Crash Protection, Clot/Clog Detection, Short Sample Detection |
| Microvolume Technology | |
|---|---|
| Automatic Sample Predilution | Samples diluted 1:5 (30 μL sample + 120 μL saline generates up to 15 tests), retained for auto-repeat until results are available |
| Predilution Tray | 120 dilution cuvettes |
| Original Sample Volume | 2 to 30 μL; average of 2-3 μL per test |
| Average Reagent Volume | 80-120 μL per test |
| Storage Capacity Onboard | 25,200 tests average; Usage of concentrated reagents increases maximum capacity |
| Reaction Area | |
|---|---|
| Reaction Tray | 221 reusable plastic cuvettes |
| Cuvette Optical Path Length | 10 mm |
| Reaction Bath | Inert fluorocarbon oil circulation system, 37°C |
| Photometer | 14 fixed wavelengths (340, 410, 451, 478, 505, 545, 571, 596, 658, 694, 751, 805, 845, and 884 nm) |
| Light Source | 12 V, 50 W halogen lamp, cooled by forced water circulation |
| Assay Methods | Endpoint, rate reaction, 2-point rate, multipoint homogeneous immunoassay |
| Reaction Times | 3, 4, 5, 10, 15, and 21 minutes |
| Automatic Correction | Serum blank, cell blank, measurement point change, sample volume change in reassay |
| Point Forwarding | Automatically extends linearity over assay range samples |
| Reagent Handling | |
|---|---|
| Reagent Tray | 2 trays, 56 positions each, refrigerated |
| Reagent Capacity Onboard | 52 colorimetric methods |
| Dispensing System | 2 probes with Liquid Level Sensing and Liquid Surface Verification |
| Reagent Wedges | 20, 40, 70 mL bar-code-labeled wedges |
| Reagent Inventory Management | Tracks tests remaining, lot number, onboard stability, and expiration date |
| Reagent Dilutions | Capability to dilute concentrated reagents onboard |
| Onboard Stability | Up to 60 days |
| Open System Capability | |
|---|---|
| Channels | 200 channels, includes user-defined applications |
| 3rd Party Applications | Varies by country, can be configured on system |
| ISE | |
|---|---|
| ISE | Indirect simultaneous measurement of Na+, K+, Cl - |
| Sample Volume | 22 μL for all three tests |
| Priming | Automatic priming cycle |
| Electrode Shelf Life | 30,000 samples or 3 months |
| Throughput Rate | 600 tests/hour; 200 tubes/hour |
| Calibration/QC | |
|---|---|
| Calibration Interval | Up to 60 days, tracked by software |
| Auto-calibration/Auto-QC | User-defined time interval or with new reagent container |
| View Calibration/QC Data | Graphical display of calibration curves and QC; Siemens Remote Service QC monitoring |
| Calibration/Control Tray | 61 refrigerated positions for calibrators, controls, and diluents |
| Data Management | |
|---|---|
| Operating Computer | Windows® XP, 1 GB RAM, touch screen monitor 19” |
| System Documentation | Operator manual and assay sheets online |
| Host Interface | RS 232C bidirectional |
| Data Storage | 70,000 patient tests |
| Onboard Maintenance Logs | Schedule and monitor routine maintenance activities via software |
| Host Query | ASCII; system requests work order or batch of work orders from host |
| General Specifications | |
|---|---|
| Power Requirements | 200/220/230/240 V +/– 10%, 20 A, 50/60 Hz, 3 KVA |
| Water Requirements | Deionized water from pressurized water (10-30 psi/169-207 KPa) Average Consumption: 30 liters per hour |
| Drain Requirements | Minimum of 40 liters per hour |
| Dimensions | ADVIA 1800: 44.6 (h) x 58.3 (w) x 34.5 (d) in, 113.3 (h) x 148.0 (w) x 87.6 (d) cm |
| Weight | ADVIA 1800: 1,323 lbs (600 kg) |
| Compliance | UL, cUL, CE |
| Noise Specifications | Open cover less than 70 db |
| Average Heat Output | 4,299 BTU/hour @ 50 Hz, 3,023 BTU/hour @ 60 Hz |
| Operating Temperature Range | 18°-30°C/64°-86°F |
| Ambient Humidity | 40%-70% |
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Related Products, Services & Resources
* Alliance Application manufactured and distributed by Siemens Healthcare Diagnostics.
† Also available in concentrated version.
‡ ADVIA Chemistry XPT System supports concentrated version only.
§ Available only in concentrated version.
** Not available for sale in the U.S.
†† Not currently available on the ADVIA Chemistry XPT System.
‡‡ Alliance Application manufactured by third party, distributed by Siemens Healthcare Diagnostics.
§§ Syva application. Restricted in the U.S. to law enforcement-related use (forensic use only).
Due to local regulations, not all products are available in all countries.
The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.