Clinical White Papers

This white paper describes quantification methods used for amyloid and tau PET in syngo.MI Neuro Cortical Analysis. For over a decade, syngo.MI Neuro has had an analysis workflow dedicated to automated SUVr-based quantification of amyloid PET imaging. This workflow, referred to as Cortical Analysis, provides the reading physician with a user-friendly software tool that enables qualitative and quantitative assessments of amyloid PET brain studies with all three approved radiotracers. 

The Cortical Analysis workflow within syngo.via MI Neurology provides conversion of SUVr values to the Centiloid scale for all three commercially available PET amyloid tracers, using five different combinations of cortical target and reference regions. This white paper features validation experiments that demonstrate that the implemented SUVr-to-CL calibration equations result in reliable Centiloid values and cut-off points comparable with previously published data.

Motion mitigation technologies in SPECT/CT provide significant advantages, including improved resolution recovery and artifact reduction. This white paper illustrates how rMC Pro and rMC automate the motion correction process, minimizing user-driven variability and ensuring more consistent, reproducible results.

The potential of SPECT/CT in neurological imaging was expanded with SMARTZOOM HRX, which delivers high resolution and extended magnification. This white paper provides a comprehensive review of SMARTZOOM HRX, including the rationale behind its development and its intended clinical applications.

Cardio Direct is an innovative, time-of-flight, data-driven motion correction solution, exclusive to Biograph Trinion PET/CT. This white paper demonstrates how Cardio Direct leverages ultra-fast TOF performance to deliver a motion correction solution that enhances the interpretation and quantification accuracy of cardiac perfusion images.

This white paper provides a brief overview of the technical aspects of IQ•SPECT, highlighting normal patterns and variations. It also presents clinical examples of ischemia and infarction to help nuclear cardiologists become familiar with IQ•SPECT.

PET/CT plays an increasingly important role in the appropriate clinical setting in both initial and subsequent treatment strategies in melanoma management. Read the white paper to discover the value PET/CT imaging can have for melanoma.

Skeletal scintigraphy has been a cornerstone of nuclear medicine for decades. Explore clinical examples that highlight enhanced image quality in bone scintigraphy, made possible by xSPECT Bone technology.

xSPECT Quant for the absolute quantification of ¹⁷⁷Lu, ¹¹¹In, ⁹⁹mTc,¹²³I and ¹³¹I marks a major step toward standardizing and expanding evidence-based medicine in radionuclide imaging. Learn more about xSPECT Quant technology.

xSPECT reconstruction offers a deeper integration of SPECT and CT data. This white paper outlines the basics of xSPECT reconstruction for SPECT/CT and highlights its advantages over traditional methods.