xSPECT Technology
The complete integration of SPECT and CT

Bone scan with quantification
xSPECT Technology
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xSPECT™ technology, completely integrates SPECT and CT data during image reconstruction for sharp clinical detail and accurate measurement of disease. The high resolution of xSPECT Bone™ helps you to distinguish bone metastases from surrounding tissue to accurately localize infection and injury. To track patients’ progress over time, xSPECT Quant™ standardizes uptake values for reliable disease detection and evaluation of therapy response.

Features & Benefits


The inability to properly identify and localize small lesions can lead to inaccurate interpretation and unnecessary procedures, potentially increasing costs and risk for both the patient and healthcare providers.

By using the CT as the frame-of-reference for image reconstruction, xSPECT Bone™ can extract a zone map with different tissue segments to delineate the boundaries of the nuclear uptake during SPECT reconstruction. Through this deep integration of SPECT and CT data, xSPECT Bone can help you clearly identify disease not easily seen with conventional SPECT.

And the need for costly CT, MR, or biopsy follow-ups can potentially be reduced with xSPECT Bone, which offers higher image resolution and diagnostic relevance1.

xSPECT Quant

The need to provide outcome-based medicine can lead to operational inefficiencies in scheduling and performing unnecessary procedures due to uncertain results.

The first automated, accurate and reproducible quantification for 99mTc, 123I, 177Lu, 111In, and 131I2, xSPECT Quant™ extends advanced SPECT quantification from general nuclear medicine and bone studies to indications including neurological disorders, neuroendocrine tumors, neuroblastoma, thyroid, and prostate cancers.

xSPECT Quant is the first and only technology to use a 3% National Institute of Standards and Technology (NIST) traceable precision source3, enabling standardization of uptake values across different cameras, dose calibrators and facilities, for reliable disease detection and evaluation of therapy response.

The absolute quantification capabilities of xSPECT Quant also can facilitate theranostics, an emerging approach employing radioactive isotopes that emit energies to not only image but also treat the patient’s disease.

Broad Quantification

Broad Quantification™2 utilizes xSPECT™ technology for accurate images and reproducible quantification. It is built upon the core foundation of xSPECT technology.

With the use of workflow-guided manual calibrations, Broad Quantification integrates several xSPECT technology corrections during reconstruction of SPECT images to produce accurate images and reproducible quantitative values.

Broad Quantification may be utilized as a standalone quantification solution or in combination with xSPECT Quant to provide accurate and reproducible quantification for the nearly all isotopes and collimators used in your imaging facility.

Broad Quantification

  • Workflow-enhanced convention quantification
  • Accuracy and reproducibility of quantitative values to the dose calibrator
  • For common SPECT isotopes and parallel-hole collimators

General Requirements


Minimum Software Version

MI SPECT VB10 software version or higher


Please Note: Additional technical pre-requisites may apply. Upon receiving your request, your local Siemens representative will clarify whether your system meets the requirements.

Related Products, Services & Resources

1A. H. Vija, et al; “Evaluation of image quality and clinical acceptance of HD-Bone, a novel multimodal SPECT/CT reconstruction method for Tc99m diphosphonate imaging” - J Nucl Med. 2013; 54 (Supplement 2):339.

2xSPECT Quant 131I is not commercially available in all countries. Due to regulatory reasons, its future availability cannot be guaranteed. Please contact your local Siemens organization for further details.

3Data on file.

* Images displayed in the page header are courtesy of Bundeswehrkrankenhaus Ulm, Germany.