Fit Upgrade to Biograph Vision 600 PET/CT

Enhance your clinical performance by upgrading your existing Biograph Vision 450 system to Biograph Vision 600. The modular detector design of Biograph Vision enables seamless in-field exchange of the detector electronics assembly (DEA) within the shell of the gantry.

Siemens Healthineers Biograph Vision PET/CT scanner

Benefits

MI Biograph Vision PET/CT Optiso UDR detector product image

Exchange existing detectors with brand-new DEAs and Optiso UDR detectors

30% more coverage per bed position enables faster whole-body exams

A 33% increase in detector size and 30% increase in aFOV allows for up to 80% increase in effective sensitivity, enabling reduced dose and scan time¹
Greater sensitivity improves detectability of small lesions, enhancing clinical and research capabilities

On-site upgrades reduce time, complexity, and cost compared to new system installation—improving operational efficiency and minimizing scanner downtime

Same user interface makes it easy for staff to adapt to upgraded capabilities

Re-use of components compared to new systems contributes to an environmentally friendly, circular business approach

Exchange existing detectors with brand-new DEAs and Optiso UDR detectors

Evidence

Biograph Vision clinical image gallery - Case 8, image 1

Data courtesy of Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.

Case 6

High-quality myocardial perfusion imaging with less than half (18.9 mCi/700 MBq) of the typical ⁸²Rb dose¹

3.2-mm LSO crystals mean better definition of myocardial wall/intraventricular cavity
Excellent images with less than half of the conventional ⁸²Rb (40 mCi/1480 MBq)
Accurate MBF quantification as detection saturation is not an issue

Biograph Vision 600 PET/CT
Scan acquisition: 220 x 220 matrix, PSF+TOF, 4i5s
Scan time: 6 minutes/1 bed position
Injected dose: Rubidium 82 (⁸²Rb) 18.9 mCi
(700 MBq)

CT
SAFIRE
Scan parameters: 100 kV/9 ref mAs

Biograph Vision clinical image gallery - Case 7, image 1

Data courtesy of University Medical Center Groningen, Groningen, The Netherlands.

Case 1

Outstanding image quality on a low-dose 4.1 mCi scan even at 30 seconds per bed¹

There is high image resolution due to small crystal elements, strong signal due to optimal light capture by SIPM, and enhanced image contrast due to UltraHD reconstruction
The overall result is an image with excellent anatomical detail even when acquired at lower doses and faster scan times

Biograph Vision 600 PET/CT
Scan acquisition: 440 x 440 matrix, PSF+TOF, 4i5s
Scan time: 8 bed positions reconstructed at varied times per bed
Injected dose: Fludeoxyglucose F 18 (¹⁸F FDG) Injection
4.1 mCi (150 MBq)

CT
SAFIRE
Scan parameters: 120 kV/9 ref mAs

Data courtesy of University Medical Center Groningen, Groningen, The Netherlands.

Case 2

Evaluation of a left pulmonary granuloma using low-dose 4.6 mCi (170 MBq)¹

SiPM allows better count statistics, as such, even at lower doses and faster scan times, image quality is preserved

Biograph Vision 600 PET/CT
Scan acquisition: 440 x 440 matrix, PSF+TOF, 4i5s
Scan time: 7 bed positions reconstructed at varied times per bed
Injected dose: Fludeoxyglucose F 18 (¹⁸F FDG) Injection
4.6 mCi (170 MBq)

CT
SAFIRE
Scan parameters: 100 kV/11 ref mAs

Data courtesy of University Medical Center Groningen, Groningen, The Netherlands.

Case 3

Excellent image quality in an obese patient with a low acquisition time of only 3.5 minutes

Small crystal elements mean more resolute images
ultraHD•PET allows precise localization of coincidence events, resulting in sharply defined lesions and good image contrast even in patients with high BMI

CT
SAFIRE
Scan parameters: 140 kV/13 ref mAs

Data courtesy of University Medical Center Groningen, Groningen, The Netherlands.

Case 4

Short scan times using low dose in a patient undergoing evaluation for recurrent lung cancer

Sharp delineation of mega ureter and intestinal physiological uptake even at 4 minute total scan time reflecting fast scanning potential

CT
SAFIRE
Scan parameters: 100 kV/29 ref mAs

Data courtesy of University Medical Center Groningen, Groningen, The Netherlands.

Case 5

Seven-minute head-to-toe PET/CT scan for evaluation of melanoma

Excellent image quality achieved with fast total-body scan times
Small 3.2-mm crystal elements translates into crisp image resolution
SiPM allows capture of more scintillation events resulting in a stronger signal

Biograph Vision 600 PET/CT
Scan acquisition: 440 x 440 matrix, PSF+TOF, 4i5s
Scan time: 14 bed positions reconstructed at varied times per bed
Injected dose: Fludeoxyglucose F 18 (¹⁸F FDG) Injection
8.1 mCi (300 MBq)

CT
SAFIRE
Scan parameters: 120 kV/9 ref mAs

Data courtesy of Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.

Case 6

High-quality myocardial perfusion imaging with less than half (18.9 mCi/700 MBq) of the typical ⁸²Rb dose¹

3.2-mm LSO crystals mean better definition of myocardial wall/intraventricular cavity
Excellent images with less than half of the conventional ⁸²Rb (40 mCi/1480 MBq)
Accurate MBF quantification as detection saturation is not an issue

Biograph Vision 600 PET/CT
Scan acquisition: 220 x 220 matrix, PSF+TOF, 4i5s
Scan time: 6 minutes/1 bed position
Injected dose: Rubidium 82 (⁸²Rb) 18.9 mCi
(700 MBq)

CT
SAFIRE
Scan parameters: 100 kV/9 ref mAs

Data courtesy of University Medical Center Groningen, Groningen, The Netherlands.

Case 1

Outstanding image quality on a low-dose 4.1 mCi scan even at 30 seconds per bed¹

There is high image resolution due to small crystal elements, strong signal due to optimal light capture by SIPM, and enhanced image contrast due to UltraHD reconstruction
The overall result is an image with excellent anatomical detail even when acquired at lower doses and faster scan times

CT
SAFIRE
Scan parameters: 120 kV/9 ref mAs

Data courtesy of University Medical Center Groningen, Groningen, The Netherlands.

Case 2

Evaluation of a left pulmonary granuloma using low-dose 4.6 mCi (170 MBq)¹

SiPM allows better count statistics, as such, even at lower doses and faster scan times, image quality is preserved

CT
SAFIRE
Scan parameters: 100 kV/11 ref mAs

Data courtesy of University Medical Center Groningen, Groningen, The Netherlands.

Case 3

Excellent image quality in an obese patient with a low acquisition time of only 3.5 minutes

Small crystal elements mean more resolute images
ultraHD•PET allows precise localization of coincidence events, resulting in sharply defined lesions and good image contrast even in patients with high BMI

CT
SAFIRE
Scan parameters: 140 kV/13 ref mAs

Data courtesy of University Medical Center Groningen, Groningen, The Netherlands.

Case 4

Short scan times using low dose in a patient undergoing evaluation for recurrent lung cancer

Sharp delineation of mega ureter and intestinal physiological uptake even at 4 minute total scan time reflecting fast scanning potential

CT
SAFIRE
Scan parameters: 100 kV/29 ref mAs

Data courtesy of University Medical Center Groningen, Groningen, The Netherlands.

Case 5

Seven-minute head-to-toe PET/CT scan for evaluation of melanoma

Excellent image quality achieved with fast total-body scan times
Small 3.2-mm crystal elements translates into crisp image resolution
SiPM allows capture of more scintillation events resulting in a stronger signal

CT
SAFIRE
Scan parameters: 120 kV/9 ref mAs

Data courtesy of Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.

Case 6

High-quality myocardial perfusion imaging with less than half (18.9 mCi/700 MBq) of the typical ⁸²Rb dose¹

3.2-mm LSO crystals mean better definition of myocardial wall/intraventricular cavity
Excellent images with less than half of the conventional ⁸²Rb (40 mCi/1480 MBq)
Accurate MBF quantification as detection saturation is not an issue

Biograph Vision 600 PET/CT
Scan acquisition: 220 x 220 matrix, PSF+TOF, 4i5s
Scan time: 6 minutes/1 bed position
Injected dose: Rubidium 82 (⁸²Rb) 18.9 mCi
(700 MBq)

CT
SAFIRE
Scan parameters: 100 kV/9 ref mAs

Technical Details

Technical Specifications

Biograph Vision 600
Bore diameter: 78 cm
Tunnel length: 136 cm
Table capacity: 227 kg (500 lb)

Biograph Vision 450
Bore diameter: 78 cm
Tunnel length: 136 cm
Table capacity: 227 kg (500 lb)

Technical Specifications

Biograph Vision 600
Axial field of view: 26.3 cm
Crystal size: 3.2 x 3.2 x 20 mm
SiPM coverage of crystal array: 100%
Effective sensitivity: 175 cps/kBq (considering a 35-cm object size)
Effective peak NEC rate: 3,132 kcps ≤ 30 kBq/cc (considering a 35-cm object size)
Time-of-flight performance: 214 ps

Biograph Vision 450
Axial field of view: 20 cm
Crystal size: 3.2 x 3.2 x 20 mm
SiPM coverage of crystal array: 100%
Effective sensitivity: 97 cps/kBq (considering a 35-cm object size)
Effective peak NEC rate: 1,746 kcps ≤ 30 kBq/cc (considering a 35-cm object size)
Time-of-flight performance: 214 ps

Learn more about Biograph Vision

Get product brochure (pdf)

Biograph Vision and Biograph Vision.X PET/CT are not commercially available in all countries. Future availability cannot be guaranteed.
¹ Based on bench testing, improved sensitivity, and TOF performance per NEMA NU-2:2018. Please refer to the approved PET prescribing information for dosing and administration instructions. NEMA performance measures represent typical values derived from internal testing. All measurements are performed with the factory lower level discriminator (LLD) setting of 435 keV.
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Fit Upgrade to Biograph Vision 600 PET/CT

Benefits

Evidence

Case 1Outstanding image quality on a low-dose 4.1 mCi scan even at 30 seconds per bed1

Technical Details

Learn more about Biograph Vision

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Case 1

Outstanding image quality on a low-dose 4.1 mCi scan even at 30 seconds per bed¹