Lung Cancer

Lung, Cervix, and Head & Neck Cancers

Squamous Cell Carcinoma (SCC) Assay

Serial SCCA measurements aid in the assessment of disease recurrence, residual disease following treatment, and response to therapy.1 The Siemens Healthineers SCC assay, available on the Atellica® IM Analyzer and ADVIA Centaur® Immunoassay Systems is a valuable tool for the assessment and monitoring of squamous cell carcinoma in the head, neck, lung and cervix.

Squamous Cell Carcinomas (SSC) is an epithelial malignancy that can arise from different tissue types including lung, cervix, esophagus, anal canal, skin, and head and neck.2 Squamous Cell Carcinoma Antigen (SCCA) concentrations are elevated in the blood of patients with cervical, lung, and head and neck cancers. More than 90% of head and neck cancers, 30% of Non-Small Cell Lung cancers2 and 80% of cervical cancers are SCCs.3 Advanced stages of these cancers are associated with higher SCCA concentrations especially in lung and cervix.

SCC of the Lungs 

SCC of the Cervix

SCCA is considered the most useful marker for cervical SCC. The European Group of Tumor Markers (EGTM) recognizes SCCA as the tumor marker of choice for the follow-up of cervical cancer. Most cases are caused by infection with human papillomavirus (HPV), which is preventable with a vaccine.

SCC of the Head and Neck (SCCHN)

SCCA is used as a tumor marker for recurrence of squamous cell carcinoma in various sites, including head and neck. Studies suggest that its high serum levels are correlated to some clinical features, such as nodal metastasis.
Atellica SCC Assay Kit

The Siemens Healthineers SCC assay can accurately detect SCCA concentrations, which in conjunction with other clinical and laboratory findings, aids clinicians in treating their patients with squamous cell carcinomas.

  • Rapid and precise measurement of SCC antigen concentrations to monitor disease progression and treatment.
  • Utilizes trusted Acridinium Ester, technology, coupled with two highly specific monoclonal antibodies. 
  • Confidence in results with an assay that detects equimolar SCCA1 and SCCA2 enabling measurement of total SCCA.16