ADVIA 1800 Chemistry System

ADVIA 1800 Chemistry System

Pushing the limit of productivity

The ADVIA® 1800 Clinical Chemistry System pushes the limit of productivity. Its extensive menu allows integration of testing for clinical chemistry, drugs-of-abuse, therapeutic drug monitoring (TDM) and specific proteins such as cystatin C and CardioPhase® hsCRP. The ADVIA 1800 Clinical Chemistry System offers:

  • Throughput of up to 1,800 tests per hour to keep pace with workload peaks
  • 200 basic metabolic panels per hour to meet turnaround-time demands
  • Large onboard reagent capacity and optional concentrated reagents to reduce interruptions
  • Optimal standardization of reagents and systems for efficient consumable usage
  • Refrigerated onboard storage of controls and reagents for extended stability and increased productivity
  • Automation-ready design: no additional hardware required

Features og Fordele

The ADVIA 1800® Clinical Chemistry System pushes the limit of productivity in the core lab and meets the turnaround-time (TAT) goals of today’s laboratories. Its extensive menu allows integration of general clinical chemistry testing with testing for drugs-of-abuse, TDM, special chemistry, and specific proteins such as cystatin C and CardioPhase® hsCRP.

  

Automation-ready design

  • Point-in-space aspiration enables connectivity to a track, VersaCell® System.
  • Redundant sample loading provides built-in backup and easy handling of non-routine samples.
  • Direct sampling from track prevents tubes being detained at an analyzer and reduces aliquoting.

Peak productivity 

  • Throughput of up to 1,800 tests per hour provides the speed to keep pace with workload peaks.
  • Throughput of 200 basic metabolic panels per hour helps to meet turnaround-time demands.
  • Automatic Sample Retain technology lets you perform reruns and dilutions without the need to retrieve primary tubes.
  • Consolidate chemistry testing on one system with a comprehensive menu, consistent cycle times, speed, and open application capability.

Total system reliability 

  • Minimal-maintenance ISEs
  • Robust hardware and simplified software design, with automatic calibration validation and tracking
  • Advances in reagent onboard stability, calibration frequency, interference reduction and assay linearity expansion
  • Direct water connection
  • Remote diagnostics and Inter-Laboratory Quality Control (ILQC) options

Easy efficiency 

  • Large onboard reagent capacity and optional concentrated reagents reduce interruptions.
  • High-resolution touchscreen delivers push-button operation.
  • Reagent pause capability and onboard Sample Pause button make loading easy.
  • Minimal maintenance requirements, including no-maintenance oil bath, reduce hands-on time.
  • Sample integrity checking, include serum indices reporting, short-sample flagging, and clot detection, reducing the need for manual intervention.

Analyser

Diabetes
Fructosamine
Hemoglobin A1c (Enzymatic)

Drugs of Abuse/Toxicology
6-Acetylmorphine (6-AM)*
Acetaminophen
Amphetamines
Barbiturates
Barbiturates, Serum
Benzodiazepines
Benzodiazepines, Serum
Buprenorphine*
Cannabinoids (THC)
Cocaine Metabolite
Ecstasy
EDDP††
Ethyl Alcohol
Ethyl Glucuronide (EtG)††,§§
Fentanyl††
Methadone
Opiates
Oxycodone*
Phencyclidine
Propoxyphene
Salicylate
Tramadol††
Tricyclic Antidepressants

General Chemistry
Alanine Aminotransferase
Alanine Aminotransferase (P5P)
Albumin (BCG)†,‡
Albumin (BCP)
Alkaline Phosphatase
Ammonia
Amylase
Aspartate Aminotransferase
Aspartate Aminotransferase (P5P)
Bilirubin, Direct
Bilirubin, Total
Calcium (Arsenazo)
Calcium (CPC)
Carbon Dioxide (Enzymatic)
Chloride
Cholesterol
Cholinesterase
Creatine Kinase
Creatinine
Creatinine (Enzymatic)
Gamma-Glutamyltransferase (GGT)
Glucose (Hexokinase)
Glucose (Oxidase)
HDL Cholesterol
Iron
Lactate
Lactate Dehydrogenase (L-P)
Lactate Dehydrogenase (P-L)
LDL Cholesterol
Lipase
Magnesium
Microalbumin
Pancreatic Amylase
Phosphorus
Potassium
Sodium
Total Iron Binding Capacity (TIBC)
Total Protein
Total Protein, CSF/Urine
Triglycerides
Urea Nitrogen (BUN)
Uric Acid

Specific Proteins
α1-Acid Glycoprotein
α1-Antitrypsin
Antistreptolysin O
Apolipoprotein A1
Apolipoprotein B
β-2 Microglobulin
Complement C3
Complement C4
CRP
CRP, High Sensitivity
CRP, Wide Range
Cystatin C
Ferritin
Haptoglobin
Immunoglobulin A
Immunoglobulin G
Immunoglobulin M
Lipoprotein(a)
Prealbumin
Rheumatoid Factor
Soluble Transferrin Receptor (sTfR)§,††
Transferrin

Therapeutic Drug Monitoring
Carbamazepine
Digoxin
Gentamicin
Lamotrigine††
Levetiracetam††
Lithium
Methotrexate**,††
Phenobarbital
Phenytoin
Theophylline
Tobramycin
Valproic Acid
Vancomycin

Validity Testing
Creatinine*,§§
Nitrite*,§§
Oxidant*,§§
pH*,§§
Specific Gravity*,§§

Tekniske specifikationer

Overview

Type of System

Random, continuous access, batch, discrete processing

Throughput Rate

Up to 1800 tests/hour: 1200 tests/hour colorimetric, 600 tests/hour ISE

Onboard Assay Capacity

55, including 3 ISE

Sample Handling

Sample Tubes

5 mL, 7 mL, 10 mL tubes, 2 mL sample cups

Sample Tray

84 samples, positive sample identification

Sample Integrity Check

Qualitative check for hemolysis, lipemia, and icterus

STAT Sample Loading

84, not dedicated

Bar Codes

Interleaved 2 of 5, Code 39, Code 128, Codabar (NW7)

Auto-repeat

Automatic repeat testing from the retained prediluted sample or original sample

Auto-dilution

Automatic dilution from retained prediluted sample

Auto-reflex Testing

Automatic ability to perform three additional tests based on results of first test

Primary Probe

Liquid-level sensing, crash protection, clot/clog detection, short-sample detection

Microvolume Technology

Automatic Sample Predilution

Samples diluted 1:5 (30 μL sample + 120 μL saline generates up to 15 tests), retained for auto-repeat until results are available

Predilution Tray

120 dilution cuvettes

Original Sample Volume

2-30 μL; average of 2-3 μL per test

Average Reagent Volume

80-120 μL per test

Onboard Storage Capacity

25,200 tests average; usage of concentrated reagents increases maximum capacity

Reaction Area

Reaction Tray

221 reusable plastic cuvettes

Cuvette Optical Path Length

10 mm

Reaction Bath

Inert fluorocarbon oil circulation system, 37°C

Photometer

14 fixed wavelengths (340, 410, 451, 478, 505, 545, 571, 596, 658, 694, 751, 805, 845, and 884 nm)

Light Source

12 V, 50 W halogen lamp, cooled by forced water circulation

Assay Methods

Endpoint, rate reaction, 2-point rate, multipoint homogeneous immunoassay

Reaction Times

3, 4, 5, 10, 15, and 21 minutes

Automatic Correction

Serum blank, cell blank, measurement point change, sample volume change in reassay

Point Forwarding

Automatically extends linearity over assay range samples

Reagent Handling

Reagent Tray

2 trays, 56 positions each, refrigerated

Reagent Capacity Onboard

52 colorimetric methods

Dispensing System

Two probes with Liquid Level Sensing and Liquid Surface Verification

Reagent Wedges

20, 40, 70 mL bar-code-labeled wedges

Reagent Inventory Management

Tracks tests remaining, lot number, onboard stability, and expiration date

Reagent Dilutions

Capability to dilute concentrated reagents onboard

Open System Capability

Channels

200 channels, includes user-defined applications

3rd Party Applications

Varies by country, can be configured on system

ISE

ISE

Indirect simultaneous measurement of Na+, K+, Cl -

Sample Volume

22 μL for all three tests

Priming

Automatic priming cycle

Electrode Shelf Life

30,000 samples or 3 months

Throughput Rate

600 tests/hour; 200 tubes/hour

Calibration/QC

Calibration Interval

Up to 60 days, tracked by software

Auto-calibration/Auto-QC

User-defined time interval or with new reagent container

View Calibration/QC Data

Graphical display of calibration curves and QC; Siemens Remote Services QC monitoring

Calibration/Control Tray

61 refrigerated positions for calibrators, controls, and diluents

Data Management

Operating Computer

WINDOWS XP, 1 GB RAM, 19-inch touchscreen monitor

System Documentation

Operator manual and assay sheets online

Host Interface

RS 232C bidirectional

Data Storage

70,000 patient tests

Onboard Maintenance Logs

Schedule and monitor routine maintenance activities via software

Host Query

ASCII; system requests work order or batch of work orders from host

General Specifications

Power Requirements

200/220/230/240 V ± 10%, 20 A, 50/60 Hz, 3 KVA

Water Requirements

Deionized water from pressurized water (10-30 psi/169-207 KPa) Average consumption: 30 liters per hour

Drain Requirements

Minimum of 40 liters per hour

Dimensions

44.6 (h) x 58.3 (w) x 34.5 (d) in, 113.3 (h) x 148.0 (w) x 87.6 (d) cm

Weight

 1,323 lb (600 kg)

Compliance

UL, cUL, CE

Noise Specifications

Less than 70 db with cover open

Average Heat Output

4,299 BTU/hour @ 50 Hz, 3,023 BTU/hour @ 60 Hz

Operating Temperature Range

18°-30°C/64°-86°F

Ambient Humidity

40-70%