INNOVANCE reagentsSupporting early diagnosis, treatment, and management of COVID-19 infections
In hospitalized COVID-19 patients, elevated D-dimer levels have been found to be strongly associated with disease severity1 and even mortality2 reflecting the procoagulant status and high thrombotic risk observed in many COVID-19 patients.3,4 Therefore, the monitoring of D-dimer levels is currently highly recommended for hospitalized COVID-19 patients to stratify their thrombotic risk including testing for deep vein thrombosis (DVT) and pulmonary embolism (PE) and guiding treatment over the course of the disease.4,5
INNOVANCE D-Dimer Assay
Our INNOVANCE D-Dimer Assay provides results in 11 minutes or less and provides the clinical performance needed for a broader spectrum of clinical diagnosis, monitoring, and follow-up. Learn more.
Treating COVID-19 patients with anticoagulants has been associated with improved outcomes, both in and out of the intensive care unit setting. A study found that 62.7% of intubated patients who were not treated with anticoagulants died, compared to 29.1% of intubated patients treated with anticoagulants.6
INNOVANCE Heparin Assay
Our INNOVANCE Heparin Assay quantitatively determines the activity of unfractionated (UF) and low-molecular-weight (LMW) heparin in citrated plasma. Liquid reagents and a single hybrid calibration curve for UF and LMW heparin help deliver precise results in fewer steps.
Accurate antithrombin measurement in COVID-19 patients undergoing anticoagulant treatment may be useful to determine the efficacy of anticoagulant therapy as antithrombin levels might be reduced.4
INNOVANCE Antithrombin Assay
Our INNOVANCE Antithrombin Assay is a proven assay to diagnose antithrombin defects and monitor antithrombin levels.
Learn more about our comprehensive portfolio of assays for detection and monitoring of coagulation disorders.
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1 Lippi G, Favaloro EJ. D-dimer is associated with severity of coronavirus disease 2019: a pooled analysis. Thromb Haemost. 2020.
2 Zhang L, et al. D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19. J Thromb Haemost. 2020.
3 Bikdeli B, et al. COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up. J Am Coll Cardiol. 2020.
4 Zhai Z, et al. Prevention and treatment of venous thromboembolism associated with coronavirus disease 2019 infection: a consensus statement before guidelines. J Thromb Haemost. 2020.
5 Tachil, et al. ISTH interim guidance on recognition and management of coagulopathy in COVID-19. J Thromb Haemost. 2020;18:1023-26
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