syngo RESOLVE (readout segmentation of long variable echo-trains) is a revolutionary new approach for obtaining high quality DWI images even in body regions which are strongly affected by susceptibility artifacts. It is not only largely free of distortions, but can also deliver sharp imaging at higher spatial resolution. syngo RESOLVE is especially attractive for the evaluation of smaller lesions in a wide range of DWI and DTI examinations.

  • Can be useful in differential diagnosis of benign versus malignant lesions in all anatomical regions.
  • Enables higher resolution fiber tracking for neuroscience studies.
  • Main application areas: brain, spine, breast and prostate imaging.

Features & Benefits

syngo RESOLVE Graph

syngo RESOLVE uses the same diffusion preparation as single-shot EPI, however, the k-space trajectory is divided into multiple segments in the readout direction, which allows for a TE and and an encoding-time reduction increasing image quality.

  • High-resolution DWI and DTI
  • Reduced susceptibility and blurring artifacts, insensitive to motion-induced phase errors
  • Reduced SAR, when compared to alternative TSE-based methods
  • Increase in clinical relevance and diagnostics confidence
  • Relevant for a variety of clinical and neuroscience studies

Additional information
The rate of water diffusion in different tissue types correlates strongly with their physiological state, and might be altered as a result of disease. Diffusion Weighted Imaging (DWI) provides a way to measure and visualize abnormal diffusivity, revealing lesions which would often go unnoticed with conventional anatomical MR or CT imaging alone. Due to the large diagnostic value of this technique, and despite some challenges in certain body regions at higher field strengths, DWI is now broadly used in clinical routine.

Clinical Use

Experience a higher level of diagnostic confidence with sharp, high-resolution diffusion-weighted images largely free of geometric distortions.

Left: Hippocampal lesion (Image: Ebara Hospital, Tokyo, Japan - MAGNETOM Trio, A Tim System)

Right: Spine Post accident, TH6 and TH12 fracture (Image: Singapore General Hospital, Singapore - MAGNETOM Avanto)

Left: Breast Carcinoma (Image: AKH, Vienna, Austria - MAGNETOM Trio, A Tim System)

Right: Prostate Carcinoma (Image: National University Hospital, Singapore - MAGNETOM Skyra)

Left: Medulloblastoma 12 year old male (Image: Children's MRI Centre, Royal Children's Hospital, Melbourne, Australia - MAGNETOM Verio)

Right: Drop metastases to the spine 2 year old female (Image: Children's Healthcare of Atlanta at Scottish Rite, Atlanta, USA - MAGNETOM Avanto)


MAGNETOM Flash 2/2012

High-Resolution DWI in Brain and Spinal Cord with syngo RESOLVE (Cohen-Adad)
“At all field strengths, the sequence promises to be useful in a number of clinical applications to characterize the diffusion properties of pathology with high resolution and a low level of image artifact."2

Early clinical evidence

Echo Planar Diffusion-Weighted Imaging: Possibilities and Considerations with 12- and 32-Channel Head Coils. (Morelli, et al)

“The utility of single-shot (ss) and an approach to readout-segmented (rs) echo planar imaging (EPI) are examined. Substantial image quality improvements are found with rs-EPI.”

J Clin Imaging Sci, 2(1), 1-6, 2012

Benign versus metastatic vertebral compression fractures: combined diffusion-weighted MRI and MR spectroscopy aids differentiation. (Rumpel, et al)

“Diffusion-weighted read-out-segmented echoplanar imaging improves spinal image quality.”

Magn Reson Med Sci, 10(4), 269-275, 2011

Anatomical details of the brainstem and cranial nerves visualized by high resolution readout-segmented multi-shot echo-planar diffusion-weighted images using unidirectional MPG at 3T. (Nagawa, et al)

“DWI by rs-EPI was significantly better than DWI by single-shot EPI for visualizing the medial longitudinal fasciculus, lateral lemniscus, corticospinal tract, and seventh/eighth cranial nerves and offered significantly less distortion of the brainstem.”

Drop metastases

Drop metastases to the pediatric spine revealed with diffusion-weighted MR imaging. (Hayes, et al)

“DWI of the spine has not been clinically useful in children because of susceptibility artifacts and lack of spatial resolution. A new technique, readout-segmented echo planar imaging (EPI), has improved these images, allowing for identification of hypercellular drop metastases.”

readout-segmented echo-planar

Readout-segmented echo-planar imaging improves the diagnostic performance of diffusion-weighted MR breast examinations at 3.0 T (Bogner, et al)

“Readout-segmented echo-planar imaging reached a higher diagnostic accuracy for the differentiation of benign and malignant breast lesions.”

General Requirements

  • MAGNETOM Prisma
  • MAGNETOM Amira
  • MAGNETOM Altea
  • MAGNETOM Verio
  • MAGNETOM Skyra
  • MAGNETOM Lumina

syngo MR D11
syngo MR D13

Please Note: Additional technical pre-requisites may apply. Upon receiving your request, your local Siemens representative will clarify whether your system meets the requirements.

Subscription Button Icon
Be the first to know about our events, training, and news