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  5. Anti-Müllerian Hormone (AMH) Assay
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Anti-Müllerian Hormone (AMH) Assay

Supporting the Fertility Journey through Trusted Science

AMH Assay Benefits

Delivering accurate, reliable, and convenient AMH results, enabling women and their doctors to plan appropriately for initiating fertility treatments with reasonable expectations.

illustration of an ovary

Accurately assess fertility potential

Demonstrates strong clinical performance for ovarian reserve (sensitivity 90.5%, NPV 82.8%)2

patient management icon

Enhance confidence in patient management

Provides highly precise results across the measuring interval (CVs <4%) as shown in published studies2,3

data results illustration

Optimize workflow efficiency

Consolidates testing on one platform with a comprehensive menu of reproductive endocrinology assays

Technical Specifications

Platform

Atellica IM/CI

ADVIA Centaur XP / XPT

ADVIA Centaur CP

Sample Type

Serum and Plasma

Serum and Plasma

Serum and Plasma

Time to First Result

28 min

28 min

28 min

Sample Volume (μL)

100μL

100μL

100μL

Assay Range

0.043–24.0 ng/mL
(0.307–171 pmol/L)

0.043–24.0 ng/mL
(0.307–171 pmol/L)

0.043–24.0 ng/mL
(0.307–171 pmol/L)

Calibration Interval

Lot calibration: 52 days
Pack calibration: 42 days

28 days

21 days

Onboard Stability

Atellica IM:  70 days
Atellica CI:   90 days

70 days

56 days

Detection Capability

LoB: 0.010 ng/mL(0.071 pmol/L)
LoD: 0.020 ng/mL (0.143 pmol/L)
LoQ: 0.043 ng/mL (0.307 pmol/L)

LoB: 0.010 ng/mL(0.071 pmol/L)
LoD: 0.020 ng/mL (0.143 pmol/L)
LoQ: 0.043 ng/mL (0.307 pmol/L)

LoB: 0.010 ng/mL(0.071 pmol/L)
LoD: 0.020 ng/mL (0.143 pmol/L)
LoQ: 0.043 ng/mL (0.307 pmol/L)

Additional Resources

image of visual guide

Visual Guide

Answer the need for rapid and precise fertility testing solutions. Download the Visual Guide to learn more about the clinical performance of the AMH assay.

Clinical Brief cover

Clinical Brief

Recent trends in reproduction establish the need for better fertility testing. Download the Clinical Brief today to learn the facts about fertility and the AMH assay and review AMH methods comparison data. You can also directly visit the publishers’ websites to access copies of two AMH methods comparison studies below.

Doctor having a discussion with pregnant couple

Reproductive Endocrinology Portfolio

A long-standing market leader in reproductive endocrinology, Siemens Healthineers offers a broad range of systems and fertility tests to address the various clinical needs in reproductive health.

Cover of Endocrines

Analytical Characteristics and Clinical Performance of Anti-Müllerian Hormone Immunoassay on the ADVIA Centaur® System: A Comparison with Other Chemiluminescent Methods

Analytical characteristics, clinical performance, and method comparison studies were performed and results were determined using ADVIA Centaur, Beckman Access® and Roche Elecsys® AMH assays, and it was determined that the ADVIA Centaur assay is essentially interchangeable with the Beckman AMH assay for acceptable ovarian reserve assessment.

Bogdanovic J, Freeman K, Brown C, Singleton R, Behera M, O’Brien JE, Zbella E, Christenson RH. Analytical Characteristics and Clinical Performance of Anti-Müllerian Hormone Immunoassay on the ADVIA Centaur® System: A Comparison with Other Chemiluminescent Methods. Endocrines. 2024; 5(4):516-528. https://doi.org/10.3390/endocrines5040037
Cover Clinical Biochemistry

Evaluation of Siemens Atellica AMH assay and comparison with Roche, Beckman and Ansh Labs

The Siemens Healthineers Atellica IM assay shows promise as an alternative method for AMH measurement, demonstrating good correlation with established assays.

Emily Shang, Hilario Agustin, Jason K.Y. Lee, Matt Scheidegger, JoAnna Jones, Charbel Abou-Diwan, Joe M. El-Khoury, Jieli Li,vEvaluation of Siemens Atellica AMH assay and comparison with Roche, Beckman and Ansh Labs,vClinical Biochemistry, Volume 135, 2025, 110863, ISSN 0009-9120, https://doi.org/10.1016/j.clinbiochem.2024.110863
1

https://www.bgsu.edu/content/dam/BGSU/college-of-arts-and-sciences/NCFMR/documents/FP/guzzo-payne-age-birth-fp-18-25.pdf

​2
Bogdanovic, J. et al, Analytical Characteristics and Clinical Performance of Anti-Müllerian Hormone Immunoassay on the ADVIA Centaur System: Comparison with Other Chemiluminescent Methods. Endocrines 2024, 5, 516–528   
3
Shang, E. et al, Evaluation of Siemens Atellica AMH assay and comparison with Roche, Beckman and Ansh Labs. Clinical Biochemistry 135 (2025) 110863, 1-4
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