Hepatitis Test SolutionsSiemens Healthineers offers a comprehensive hepatitis testing menu to simplify laboratory workflow.

Hepatitis: Combat the Silent Epidemic

Learn more about hepatitis C screening and share to help raise awareness.

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Viral hepatitis is a global health problem that affects hundreds of millions of children and adults. Although multiple pathogens have been associated with hepatitis, three in particular (hepatitis A, B, and C) are responsible for the majority of virally linked hepatitis cases. Chronic viral hepatitis B and C are a major cause of chronic liver disease, which may manifest as liver fibrosis and cirrhosis leading to liver cancer and the need for liver transplantation.

Siemens Healthineers offers hepatitis testing solutions for:

Hepatitis testing solutions
You can depend on Siemens Healthineers to provide your lab with the test accuracy and efficiency you demand for hepatitis B diagnostic testing.

The ADVIA Centaur® HBsAgII Assay is designed with patented acridinium ester (AE) technology, allowing for enhanced precision and sensitivity. Incorporating the zwitterionic AE molecule into the assay format results in greater sensitivity and improved detection of HBsAg mutants. A total of five monoclonal antibodies are used in the HBsAgII assay design, greatly improving the assay’s sensitivity and specificity.

Only the ADVIA Centaur HBsAgII Assay offers a “hot zone” and SMART algorithm for greater lab efficiency.

  • Reduce your test volumes. Samples in the hot zone (initial results ≥50 Index Units) may be reported as reactive. Only samples with initial values between 1 and <50 Index Units require further testing.
  • Improve your lab efficiency. The SMART algorithm automatically repeats testing on samples that require further analysis.

With the use of disposable sample tips on the ADVIA Centaur® Immunoassay System, potential sample carryover and subsequent risk of false positives are never a concern.

Hepatitis C

The CDC has expanded previous recommendations for hepatitis C virus (HCV) screening of all persons born between 1945 and 1965 (the so-called baby-boomer generation) for HCV infection.1

The ADVIA Centaur® HCV Assay is a true third-generation assay with the ability to detect the NS5 antibody.2 The assay design uses patented acridinium ester (AE) technology for improved sensitivity in detecting low-level analytes and better accuracy and precision.

Laboratory Testing: Importance

From diagnosis through active disease and chronic progression, laboratory testing plays an important role in the identification, treatment, and monitoring of patients with hepatitis.

  • Immunoassay testing aids in the diagnosis of viral hepatitis and may indicate if the infection is acute or chronic.
  • Nucleic acid testing (NAT) is used to confirm hepatitis diagnosis, guide treatment, and indicate prognosis.
  • Biomarkers, imaging, and biopsy help to stage the degree of fibrosis and liver injury.

If you are interested in adding Hepatitis testing to your ADVIA Centaur or Atellica Solution menu, please contact the Inside Sales Department at (800) 242-3233, option 3.

Assay Menu

Siemens Healthineers offers a comprehensive disease-management portfolio for hepatitis screening, diagnosis, and monitoring.

Siemens Healthineers provides hepatitis testing solutions for:

  • Diagnostic laboratories, with a comprehensive hepatitis assay menu on the ADVIA Centaur® Immunoassay Systems, IMMULITE® 2000/2000 XPi Immunoassay Systems, and Atellica® IM System

Screening Assays

Hepatitis A

   Anti-HAV IgM


   Anti-HAV Total


Hepatitis B




   Anti-HBc Total


   Anti-HBc IgM









   HBsAg Confirmatory

Hepatitis C