- Home
- Laboratory Diagnostics
- Hemostasis
- Coagulation Assays
- INNOVANCE VWF Ac assay

Diagnose von Willebrand disease using GPIbM technology
Features & Benefits
Diagnose the most common inherited bleeding disorder
INNOVANCE VWF Ac assay is now available to U.S. laboratories
To correctly diagnose cases involving a bleeding anamnesis or a family history of von Willebrand disease and subsequently monitor patient response to therapy, physicians require a specific test for von Willebrand factor (VWF). A functional assay is the preferred screening method for detecting quantitative as well as qualitative defects of von Willebrand factor.1
Now available for U.S. labs, the INNOVANCE® VWF Ac assay uses the guideline recommended VWF: GPIbM technology, allowing for a more accurate functional assessment of VWF with greater precision and heightened sensitivity. The GPIbM technology mimics true VWF function and detects variants missed by other assay technologies.
The INNOVANCE VWF Ac Assay Principle
- INNOVANCE VWF Ac assay uses recombinant GPIb with 2 gain of function mutations in a latex based GPIb-binding assay
- GPIb spontaneously binds to native VWF
- Ristocetin is not needed
Did this information help you?
Thank you.
James PD, et al. ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease. 2021 Jan 12 [published online].