EMIT II Plus Cocaine Metabolite AssayHigh specificity for benzoylecgonine

The EMIT® II Plus Cocaine Metabolite Assay is intended for the qualitative and semiquantitative determination of benzoylecgonine in human urine, at a cutoff value of 150 ng/mL or 300 ng/mL. The SAMHSA initial test cutoff level is 150 ng/mL.

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Features & Benefits

Cocaine is a central nervous system stimulant that is extracted from the coca plant. Cocaine base can be smoked in a form that is commonly known as “crack.” Cocaine is rapidly absorbed, especially when smoked, which is why the major metabolite, benzoylecgonine, is used for immunoassay drug screening.

The EMIT II Plus Cocaine Metabolite Assay provides:

  • High specificity for benzoylecgonine, the major metabolite of cocaine
  • Excellent precision—all within-lab (total) CVs ≤2.6% or less across the assay range
  • Dual cutoffs available with one assay
  • Ready-to-use liquid reagents, calibrators, and controls
  • 93% correlation with reference method (GC/MS)


Applications are available for the Viva-Jr®, Viva-E®, Viva-ProE®, V-Twin® drug testing systems and AU® Series analyzers.

Technical Specifications

 Assay Principle

  Homogeneous Enzyme Multiplied Immonoassay (EMIT)

 Cut-off

  150 ng/mL or 300 ng/mL

 Sample

  Urine  

 Reagent Stability

  Unopened: until expiration date. Onboard instrument: up to 4 weeks

 Calibration Frequency

  As indicated by control results