xSPECT QuantReliable SPECT/CT quantification for clinical routine

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xSPECT Quant

Conventional SPECT/CT quantification is manual and time intensive—often requiring specialized resources to manage the complexity and potential for error. As a result, quantitative SPECT/CT is rarely used clinically.

The only tool to offer automated, accurate, and reproducible quantification for a range of isotopes, xSPECT Quant™1 has paved the way for routine SPECT/CT quantification.

xSPECT Quant uniquely uses a 3% National Institute of Standards and Technology (NIST) traceable precision source, which allows you to easily standardize uptake values across different cameras, dose calibrators, and facilities.

Accurate to within 5%2, xSPECT Quant is the industry’s most precise and reproducible SPECT/CT quantitative solution. Available for 99mTc, 123I, 177Lu, and 111In imaging, xSPECT Quant enables quantification to be used clinically to more precisely detect disease and better manage therapy.

The absolute quantification capabilities of xSPECT Quant are also a basis for theranostics, the unique approach of combining diagnostics and therapy.

What experts say

John Prior, PhD, MD, FEBNMCentre Hospitalier Universitaire Vaudois (CHUV)Lausanne, Switzerland
Imaging life

Defining the quantitative future of SPECT/CT

Read about how SPECT/CT imaging is becoming a meaningful tool for determining prompt diagnoses and developing personalized treatment strategies.

To learn more about theranostics visit SPECT/CT Quantification for theranostics

Clinical image gallery

Case studies

White paper

Differentiation of a rib benign lesion from a metastasis using xSPECT Quant

  • 58-year-old patient
  • Underwent a prostatectomy
  • Underwent a 99mTc DPD bone scan as part of the initial staging


Isotope 177Lu

xSPECT Quant-based dosimetry following 177Lu PSMA4 therapy in metastatic prostate cancer

  • 82-year-old male
  • Presented with castration-resistant prostate cancer and multiple skeletal metastases
  • Treated with an intravenous infusion of 8.7 GBq of 177Lu PSMA

Additional case studies

Isotope 111In
xSPECT Quant measures pancreatic metastases' uptake and changes during diagnosis and treatment Download

Isotope 123I
xSPECT Quant helps differentiate Parkinson's disease Download

White paper

White paper

Written by A. Hans Vija, PhD, Carl von Gall, MD, and Partha Ghosh, MD
Siemens Healthineers Molecular Imaging