Next to T2- and T1-weighted images of tissue morphology, the following MRI contrasts offer additional physiological and metabolic information:
- MR diffusion-weighted imaging maps cellular density.
- Contrast-enhanced MRI allows the analysis of perfusion and vascular permeability.
- MR spectroscopy imaging adds further specificity for tumor detection by imaging abnormal metabolism.
- With bone metastases being a common complication, routine bone scans utilizing SPECT or SPECT·CT are recommended for patients with a PSA >10 ng/mL1.
- Integrated diagnostic CT performed as a part of the SPECT·CT bone procedure may help improve localization and lesion characterization.
Unique hybrids for more precise molecular imaging
Hybrid imaging modalities, such as SPECT•CT, PET•CT and MR-PET, add the value of biological information to precise anatomical information - helping physicians to clearly understand tumor characteristics for more confident disease management.
Positron Emission Tomography – Computed Tomography (PET•CT)
- PET•CT enables precise localization of the primary tumor and earlier visualization of metastatic disease.
- Usefull for primary diagnosis and follow-up for high-risk patients and those with recurrent disease.
- 18F-NaF PET•CT provides lesion detection through improved molecular resolution.
- Potential new tracers may further expand the clinical use of PET•CT for prostate cancer.
Molecular MR (MR-PET)
- Siemens offers simultaneous acquisition of whole-body MR anatomical as well as functional data and PET metabolic information in a single image.
- This unique modality helps to accurately identify and localize tumor relapse, involved lymph nodes, or distant metastases.
- With already more than 30 installed systems worldwide, Biograph molecular MR (mMRTM) has become part of clinical routine.
Computed Tomography (CT)
- Used for tumor staging, e.g. searching for metastases, and evaluation of advanced disease or in high-risk patients.
- Used for radiotherapeutical treatment planning (external beam therapy or brachytherapy)