Dimension EXL with LM Integrated Chemistry System
An integrated clinical chemistry and immunoassay analyzer with extensive onboard capacity
Expand our capabilities with productivity-enhancing features, LOCI® Advanced Chemiluminescence Technology, and a large assay capacity that can increase efficiency in low- to mid-sized laboraties.
- Consolidate workstations with a single system that integrates chemistry and immunoassay testing.
- Test from a comprehensive menu that includes critical cardiac assays and our no-pretreatment immunosuppressive drug assays.
- Achieve throughput of up to 627 tests per hour with 91 assays onboard.
Dimension® EXL™ with LM Integrated Chemistry System
Uninterrupted Processing
True Integration
Grow Your Menu
Features & Benefits
Dimension EXL with LM Integrated Chemistry System - Features & Benefits
“The Dimension® EXL™ system with the LOCI® module helps us contribute to better patient care because it’s faster and more accurate... I feel very confident about the results that we send out. I trust the instrument explicitly.”
Donna Hartsell, MT (ASCP)
Section Head of Chemistry, Caldwell Memorial Hospital
True Integration for Increased Efficiency
- Extend capabilities with a comprehensive menu, including chemistry, cardiac, thyroid, and our no-pretreatment immunosuppressive drug assays.
- Avoid splitting samples—simultaneously run all assays from one sample tube.
- Simplify your workflow—mix and match chemistry and immunoassay tests in one common reagent area.
"The comprehensive menu allows us to look at the parameters of whole disease states from a single primary tube. That’s the purpose of having just that one instrument to do everything."
Donna Hartsell, MT (ASCP)
Section Head of Chemistry, Caldwell Memorial Hospital
LOCI Technology Inside
- Experience excellent immunoassay sensitivity using small sample volumes with homogeneous LOCI® Advanced Chemiluminescence Technology.
- Produce fast and accurate results in 11–18 minutes for key critical assays.
High Productivity
- Meet workload demands with throughput of up to 627 tests/hour and electrolyte results in under a minute.
- Increase testing capabilities with 91 assays onboard and the ability to load 18 reagents at once without pausing the system.
- Respond quickly with STAT sampling from any position and a 4-minute time to first result for a basic panel.
- Save time with no manual sample pretreatment, no manual reagent preparation, and long calibration stability.
- Further simplify laboratory operations with connectivity to Siemens automation and IT solutions.
“We were looking for the complete package: one tube, one sample, broad menu, walkaway time, assay quality, backup capability, ease of use, technical service, and fiscal economy.” Jay Bosch
Medical Laboratory Technician, Beaver Dam Reference Laboratory
Assays
Anemia
Ferritin
Folate
Vitamin B12
Bone Metabolism
Vitamin D Total
Cardiac
BNP*
CKMB Mass
CardioPhase® hsCRP
High-Sensitivity Troponin I
Myoglobin
NT-proBNP
Troponin I
Diabetes
Fructosamine†,‡
Hemoglobin A1c§
Drugs of Abuse/Toxicology
6-Acetylmorphine (6-AM)**
Acetaminophen
Amphetamines
Barbiturates, Urine
Barbiturates, Serum**
Benzodiazepines, Urine
Benzodiazepines, Serum**
Buprenorphine**
Cannabinoids (THC)
Cocaine Metabolite
Ecstasy
Ethyl Alcohol
Fentanyl††,‡‡
Methadone
Methaqualone**
Opiates
Oxycodone**
Phencyclidine
Propoxyphene**
Salicylate
Tricyclic Antidepressants**
General Chemistry
Acid Phosphatase
Alanine Aminotransferase (ALT)
Albumin (BCP)
Aldolase†,‡
Alkaline Phosphatase (ALP)
Ammonia
Amylase
Aspartate Aminotransferase
Bilirubin, Direct
Bilirubin, Total
Calcium (CPC)
Carbon Dioxide
Chloride
Cholesterol
Creatinine
Creatinine (Enzymatic)
Creatine Kinase
Dibucaine Number†,‡
Gamma Glutamyltransferase (GGT)
Glucose
Glucose, Hemolyzed†,**
HDL Cholesterol
Iron
Lactate
Lactate Dehydrogenase
LDL Cholesterol
Lipase
Magnesium
Microalbumin
Pancreatic Amylase†,‡
Phosphorus
Potassium
Pseudocholinesterase
Sodium
Total Iron Binding Capacity
Total Protein
Total Protein, CSF/Urine
Triglycerides
Urea Nitrogen (BUN)
Uric Acid
Immunosuppressant Drugs
Cyclosporine§
Cyclosporine, Extended Range§
Everolimus††
Mycophenolic Acid
Sirolimus§
Tacrolimus§
Oncology
Free PSA
Total PSA
Reproductive Endocrinology
hCG
Specific Proteins
α1-Acid Glycoprotein†,‡
β-2 Microglobulin Latex†,‡
Antistreptolysin O (ASO)†,‡
Apolipoprotein A-I†,‡
Apolipoprotein B†,‡
Ceruloplasmin†,‡
Complement C3
Complement C4
CRP
CRP, Extended Range
Haptoglobin†,‡
Ig Light Chains, Type Kappa†,‡
Ig Light Chains, Type Lambda†,‡
Immunoglobulin A
Immunoglobulin G
Immunoglobulin M
Lipoprotein (a) Ultra†,‡
Prealbumin
Rheumatoid Factor (RF)†,‡
Transferrin
Therapeutic Drug Monitoring (TDM)
Amikacin**
Caffeine**
Carbamazepine
Digitoxin
Digoxin
Ethosuximide**
Gentamicin
Lidocaine
Lithium
Methotrexate**
N-Acetylprocainamide (NAPA)
Phenobarbital
Phenytoin
Procainamide
Theophylline
Tobramycin
Valproic Acid
Vancomycin
Thyroid
Free T3
Free T4
T Uptake
Total T4
TSH
Technical Specifications
| Overview | |
| System Description | Random-access clinical chemistry and immunoassay system with LOCI® chemiluminescence technology |
| Test Throughput | Performs up to 440 photometric chemistry tests per hour and 187 IMT tests per hour on serum, plasma, urine, and cerebrospinal fluid; can perform up to 167 heterogeneous immunoassay tests per hour |
| Time to First Result | IMT (NA, K, CL): 1.5 min; Electrolytes (IMT + ECO2): 2.9 min; BMP-7 Electrolytes, GLU, BUN, CREA) 4.0 min; CMP-6 (ALB, DBIL, TBIL, AST, ALT, ALP): 9.3 min; TNI: 11 min; HCG: 15.5 min |
| Assay Capacity Onboard | 91 including 3 IMT |
| Disease-state Assay Groups | Anemia, Autoimmune/Rheumatoid, Bone Metabolism, Cardiovascular, Diabetes, Drugs of Abuse/Toxicology, Hepatic Diseases, Immunosuppressive Drugs/TDM, Inflammation, Nephropathies, Nutritional Assessment, Pancreatic Disease, Oncology, Reproductive Endocrinology, Thyroid |
| Sample Handling | |
| Sample Tubes | 5 mL, 7 mL, 10 mL tubes; 1.5 mL sample cups; 1.0 mL small sample containers and pediatric tubes |
| Sample Wheel | 60 sample positions in six 10-tube segments; positive sample identification |
| STAT Handling | Not dedicated; STAT samples are processed with priority |
| Sample Integrity Check | Qualitative check for hemolysis, lipemia, and icterus; clot detection, flagging, and management; short-sample detection, flagging, and management |
| Auto-Repeat | Automatic repeat testing from the original sample |
| Sample Volume Per Test | 2–60 μL |
| Sample Dilution | Automatic dilution: 1:1.5 up to 1:200 |
| Auto-Reflex Testing | Automatic reflex testing based on results of first test |
| Primary Sample Probe | Liquid-level sensing, clot detection, short-sample detection |
| Sample Carryover Prevention | Automated wash |
| Sample Throughput | Up to 200 tubes per hour as part of the VersaCell® X3 Solution – Dimension® Suite; faster on automation |
| Bar Codes | |
| Sample Bar Codes | Code 39; Code 128; Codabar (USS); Interleaved 2 of 5 w and w/o check digit, 12 digits maximum |
| Reaction Area | |
| Reaction Cuvettes | Onboard capacity of 12,000 formed cuvettes |
| Reaction Bath | Air; incubation temperature 37°C |
| Path Length | 0.5 cm ±0.0125 cm |
| Photometer | The filter wheel holds optical filters for wavelengths of 293, 340, 383, 405, 452, 510, 540, 577, 600, 680, and 700 nm |
| Light Source | Standard tungsten halogen lamp, operation at 6.5A (6.8v) |
| Reaction Times | 1, 3, 4, 5, 10, 15, 21, and 32 minutes |
| Automatic Correction | Serum blank, cell blank, reagent blank, measurement point change, autodilution |
| Assay Technologies | LOCI, heterogeneous immunoassay, PETINIA and ACMIA, photometry, potentiometry (ISE), turbidimetric, and Emit® |
| Assay Result Calculations | Endpoint, rate, multipoint |
| Reagent Handling | |
| Reagent Tray | 2 trays, 44 positions, refrigerated between 2–8°C (36–47°F); one on the Reagent Management System (RMS) |
| Reagent Capacity Onboard | 88 Flex® Reagent Cartridges plus 3 electrolytes via the QuikLYTE® IMT |
| Dispensing System | 3 probes with liquid-level sensing |
| Reagent Cartridges | Flex Reagent Cartridges, bar coded, 15 to 360 tests/Flex |
| Average Total Reaction Volume | 350–500 μL per test |
| Reagent Integrity Control | Bar-code reagent identification; automatic inventory tracking and flagging; calibration and control validity tracking and flagging; reagent onboard tracking of tests remaining, lot number, onboard stability, and expiration date |
| Onboard Stability | Depending on assay, up to 42 days |
| Test Capacity Onboard | 25,200 tests average; 33,300 tests maximum |
| Open System Capability | |
| Channels | 110 assay channels; includes 10 channels for user-defined applications |
| IMT | |
| IMT | Indirect simultaneous measurement of Na+, K+, Cl- |
| Sample Volume | 40 μL for all three tests |
| Priming | Automatic priming cycle, no user calibration, automatic urine dilution 1:10 |
| Expected Use | 1000 samples or 5 days, whichever comes first |
| Calibration/QC | |
| Validated Calibration Interval | Up to 90 days, tracked by software, with 500 most recent calibration logs stored electronically if a system restore is required (starting with software version 10.1) |
| Auto-Calibration | Assay-specific time interval or with new reagent lot |
| Auto-QC | User-defined time interval |
| View Calibration | Graphical display of calibration curves |
| QC Data | Graphical display of QC plot (histogram or Levey-Jennings) with Westgard Rules; RealTime QC; QCC PowerPak™ efficiency package |
| User Interface/Data Management | |
| Monitor | 17-inch diagonal touchscreen with adjustable height |
| Operating Computer | Linux, 1 GB RAM |
| System Documentation | Operator manual |
| Data Storage | 100,000 patient tests (10 MB), 100,000 QC results (10 MB), 9000 calibrations (5 yrs, 18 MB) |
| Auto-System Check | User-defined time of day |
| Host Interface | RS 232C bidirectional |
| Host Query | System requests work order or batch of work orders from host |
| Remote Access and Service | Ethernet port for remote access via Siemens Remote Service (starting with software version 10.1); modem for remote diagnostic access |
| Removable Media | |
| Removable Media | CD, DVD, and USB (starting with software version 10.0) |
| General Specifications | |
| Power Requirements System | 115 VAC at 60 Hz (nominal); 11 amps max; 1.3 kW consumption in operating state 230 VAC at 50 Hz (nominal); 5.5 amps max; 1.3 kW consumption in operating state |
| Power Requirements RMS | 115 VAC at 60 Hz (nominal); 4 amps max; 450 W consumption in operating state 230 VAC at 50 Hz (nominal); 3 amps max; 450 W consumption in operating state |
| Water Specifications1 |
|
| Water System |
|
| Maximum Water Consumption | 5.0 L/hr (1.32 gal/hr) |
| Drain Requirements | 40 L/hr (10.6 gal/hr) |
| Dimensions | Normal operation: 252 cm W x 122 cm H x 132 cm D (99 in. W x 48 in. H x 52 in. D) With monitor fully extended, lids fully open, and external UPS: 255 cm W x 191 cm H x 155 cm D (100 in. W x 75 in. H x 61 in. D) |
| Weight | 496 kg (1095 lb) |
| Compliance | Complies with international environmental, health, and safety standards |
| Noise Specifications | <75 dBA at 1 m while operating |
| Average Heat Output | 1551 W/hr (5293 BTU/hr) |
| Operating Temperature Range | 18–30ºC (64–86ºF) |
| Ambient Humidity | 20–80% (noncondensing) |
References:
1. Meets the definition of CLSI Clinical Laboratory Reagent Water (Clinical Laboratory Standards Institute, C3-A4, Vol. 26, No. 22).
2. Not applicable to CLSI Clinical Laboratory Reagent Water (CLRW), but required for proper instrument performance.
Share this page:
Related Products, Services & Resources
Product availability may vary from country to country and is subject to varying regulatory requirements. Please contact your local representative for availability.
The outcomes achieved by the Siemens Healthineers customers described herein were achieved in each customer’s unique setting. Since there is no “typical” hospital and many variables exist (e.g., hospital size, case mix, level of IT adoption) there can be no guarantee that others will achieve the same results.
The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.
*Available for sale only in Japan.
†Not available for sale in the U.S.
‡Alliance Application manufactured by third party, distributed by Siemens Healthcare Diagnostics.
§No manual pre-treatment.
**Alliance Application manufactured and distributed by Siemens Healthcare Diagnostics.
††Under development. Not available for sale.
‡‡Manufactured by third party, distributed by Siemens Healthcare Diagnostics.