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  5. ADVIA Centaur XPT Immunoassay System

ADVIA Centaur XPT Immunoassay SystemAn advanced automated immunoassay analyzer designed for continuous operation

The ADVIA Centaur® XPT Immunoassay System is engineered for simplified, continuous operation and timely, trusted results.

  • Responds to peak testing needs with a throughput of up to 240 tests per hour and no-pause loading of reagents, consumables, and samples.
  • Supports comprehensive diagnoses with a menu of over 70 assays.
  • Continually expands testing with advanced acridinium ester technology—evolving chemiluminescence that provides the flexibility to meet changing clinical needs.
ADVIA Centaur XPT Immunoassay System

Caratteristiche e vantaggi

"The ADVIA Centaur XPT System exceeded our expectations. Furthermore, we could reduce the monthly maintenance by 12 hours per year and operator maintenance time by 60%."
Dr. Roberto Rosso
ASST Ovest Milano
Laboratory Supervisor
Ospedale di Magenta
Dr. Roberto RossoASST Ovest MilanoLaboratory SupervisorOspedale di Magenta
Dr. Roberto Rosso
ASST Ovest Milano
Laboratory Supervisor
Ospedale di Magenta

See the video and read the case study.

See how advanced acridinium ester chemiluminescence works

Cutting-edge AE Immunoassay Technology

  • Meet evolving clinical needs with advanced acridinium ester technology, which provides flexibility and sensitivity for new and innovative assays.
  • Manage comprehensive disease-state testing with a menu of more than 70 assays.
  • Simplify inventory management and reduce cost with the same highly stable, ready-to-use reagents used on all ADVIA Centaur analyzers.
Learn how the ADVIA Centaur XPT System reduced analyzer maintenance by 67% at ASST Ovest Milano, Ospedale di Magenta

Simplified, Continuous Operation

Learn how the ADVIA Centaur XPT System reduced analyzer maintenance by 67% at ASST Ovest Milano, Ospedale di Magenta

  • Load and unload all samples, reagents, and supplies without pausing the system.
  • Simplify operation and training with an intuitive, icon-driven user interface.
  • Reduce hands-on time with low daily maintenance and no monthly cleaning or daily startup procedures.
  • Implement new assays immediately with one easy scan of a test definition bar code.
Learn how Hospital Clinic de Barcelona improved immunoassay turnaround times

Consistent, Predictable Turnaround Time and Accuracy

Learn how Laboratory Dr. Quade and Colleagues GmbH increased overall laboratory productivity with the ADVIA Centaur XPT Immunoassay System

  • Deliver up to 240 tests per hour for fast turnaround, even during peak workload times.
  • React fast with a STAT port that allows priority sampling at any time.
  • Improve result integrity with disposable probe tips that eliminate sample-to-sample carryover.
  • Conduct automatic repeat and confirmatory testing of reactive hepatitis B surface antigen samples using Siemens Healthineers unique SMART algorithm software.
See how Labor Blackholm MVZ increased testing volume by 34% with 30% fewer analyzers

Seamless Connectivity

See how Labor Blackholm MVZ increased testing volume by 34% with 30% fewer analyzers

Assays

Anemia
Active B12
EPO
Ferritin
Folate
RBC Folate
Vitamin B12

Autoimmune
Anti-CCP

Bone Metabolism
Intact PTH
Vitamin D Total

Cardiac
BNP
CKMB
High-Sensitivity Troponin I (TNIH)
Myoglobin
NT-proBNP

Diabetes
C-Peptide
Insulin

Hepatitis
Anti-HBe
Anti-HBs 2
HAV IgM
HAV Total
HBc IgM
HBc Total
HBc Total 2
HBe Ag
HBs Ag Confirmatory
HBs AgII
HBsAgII Quant
HCV

HIV
HIV 1/O/2 Enhanced (EHIV)
HIV Combo (CHIV)

Immunosuppressant Drugs
Cyclosporine
Everolimus*
Sirolimus*
Tacrolimus*

Inflammation
IgE, Total
IL-6
LBP
TNFα*

Liver Fibrosis
Enhanced Liver Fibrosis (ELF™) Test
Test HA (ELF™ Marker)
PIIINP (ELF™ Marker)
TIMP (ELF™ Marker)

Metabolic
Cortisol
Homocysteine

Neurology
Total Tau (TTAU)*
β-Amyloid 1-42 (AB42)*

Oncology
AFP
BR 27.29
CA 125II†
CA 15-3†
CA 19-9†
Calcitonin
CEA
Complexed PSA
CYFRA 21-1*
Free PSA
Neuron Specific Enolase (NSE)*
PSA
Squamous Cell Carcinoma Antigen (SCC)*
Serum HER-2/neu

Reproductive Endocrinology
AFP
Androstenedione
Anti-Müllerian Hormone*
DHEAS
Enhanced Estradiol
Free ß-hCG
FSH
hCG
LH
PAPP-A
PlGF*
Progesterone
Prolactin
sFLT-1*
SHBG
Testosterone II

Sepsis
Procalcitonin (PCT)

Special ID
EBV-EBNA IgG*
EBV-VCA IgG*
EBV-VCA IgM*
SARS-CoV-2 IgG§
SARS-CoV-2 Total§
Syphilis
Zika Test‡

Therapeutic Drug Monitoring (TDM)
Carbamazepine
Digitoxin
Digoxin
Gentamicin
Phenobarbital
Phenytoin
Theophylline
Valproic Acid
Vancomycin

Thyroid
Anti-TgII
Anti-TPO
Free T3
Free T4
T Uptake
Total T3
Total T4
TSH3-Ultra
TSH

ToRCH
CMV IgG
CMV IgM*
Herpes-1 IgG
Herpes-2 IgG
Rubella IgGII
Rubella IgM
Toxoplasma IgG
Toxoplasma IgM

Specifiche tecniche

Product Specifications

 

System Description

Random-access immunoassay system

Test Throughput

Up to 240 tests per hour

Time to First Result

18 minutes; results every 15 seconds thereafter, assay dependent

Assays Onboard

30 assays

Disease-State Assay Groups§§

Allergy, Anemia/Iron Metabolism, Bone Metabolism, Cardiac, Diabetes, Hepatitis, HIV, Immunosuppressant Drugs, Liver Fibrosis†, Metabolic, Oncology, Reproductive Endocrinology, Sepsis†, Special ID, Therapeutic Drug Monitoring (TDM), Thyroid, ToRCH

Continuous Operation

Loading/unloading of samples and consumables at any time without interrupting system operation. Includes sample racks, STATs, reagent packs, ancillary reagent packs, reaction cuvettes, sample pipette tips, calibrators, controls, wash fluids, water, and waste.

Sample Handling

 

Sample Tubes

3 mL, 5 mL, 7 mL, and 10 mL tubes; 1 mL and 2 mL sample cups; microcontainer tubes

Sample Input

Universal 5-position rack holds multiple tube types; 180 samples fully loaded; no-pause loading and unloading

Validated Sample Types

Serum, plasma, urine (assay-dependent)

Sample Volume per Test

10–200 μL, assay-dependent

Sample Integrity Control

Pressure transducer technology with clot detection, flagging, and management; short-sample detection

STAT Handling

Dedicated STAT port accepts samples any time; STAT samples are processed with priority

Auto-repeat

User-definable

Sample Dilution

Automatic dilution varies by assay, up to 1:2500

Auto-reflex Testing

Automatic ability to perform additional tests based on results of first test

Sample Pipette Tips

840 disposable sample tip capacity

Sample Carryover Prevention

Disposable pipette tips ensure zero sample carryover

Bar Codes

 

Sample Bar Codes

Up to 20 digits; Interleaved 2 of 5; Code 39, Code 128, Codabar; A, B, and special characters (.-+/*$%)

Reaction Area

 

Reaction Cuvettes

Capacity of 1000 optical-grade plastic cuvettes

Reaction Bath

Air bath, 37°C

Assay Result Calculations

SMART algorithm software repeats and confirms reactive testing; results available as completed

Assay Technology

Chemiluminescence using Advanced Acridinium Ester

Reagent Handling

 

Reagent Tray

30-position reagent tray refrigerated between 4 and 10°C (39–50°F)

Reagent Capacity Onboard

30 assays

Reagent Containers

ADVIA Centaur® ReadyPack® (various pack sizes available)

Reagent Integrity Control

Bar-code reagent identification, automatic inventory tracking and flagging, calibration valid tracking and flagging, reagent onboard stability tracking and flagging, reagent expired/reagent low flagging

Onboard Stability

28 days (average)

Reagent Mixing

ADVIA Centaur ReadyPacks automatically rocked onboard

Ancillary Reagents

25-position ancillary reagent tray cooled 4–8°C (39–46°F)

Calibration/QC

 

Auto-calibration/Auto-QC

Available automatic QC ordering by test, control, date, and time

QC Data

Advanced QC package includes Levey-Jennings plots and Westgard rules

User Interface/Data Management

 

Monitor

22-inch diagonal high-resolution LCD touchscreen with adjustable height

Operating System

Microsoft Windows 7

System Documentation

Operator manual, quickstart guide, and context-sensitive online help

Data Storage

1,000,000 test/QC results; 500,000 can be historical; can archive to removable media

Onboard Maintenance Logs

Yes

Host Interface

RS232C bidirectional and host query; Ethernet connection available

Host Query

Yes

Remote Access & Service

1000Base-T Ethernet port for remote access and modem for Siemens Remote Service

Removable Media

 

Removable Media

CD, DVD, or USB

General Specifications

 

Power Requirements

200-240 V at 50/60 Hz; 1.2 kW maximum

Maximum Water Consumption

2.5 liters (0.6 gallons) per hour

Drain Requirements

Minimum of 2.5 liters (0.6 gallons) per hour

Dimensions

With monitor: 167 (h) x 196 (w) x 104 (d) cm; 66 (h) x 77 (w) x 41 (d) in.
Without monitor: 133 (h) x 196 (w) x 104 (d) cm; 52 (h) x 77 (w) x 41 (d) in.

Weight

585 kg (1289 lb)

Compliance

Complies with international environmental, health, and safety standards

Noise Emission

65 dB maximum

Processing Heat Output

5100 BTU/hour

Ambient Temperature

18–30°C (64–86°F)

Ambient Humidity

20–80% noncondensing

Floor Load-Bearing Requirement

412 kg/m2 (84 lb/ft2)

* Under development. Not available for sale.

† CA 125II , CA 19-9 and CA 15-3 are trademarks of Fujirebio Diagnostics, Inc.  

‡ Limited distribution

§ This test has not been FDA cleared or approved. This test has been authorized by FDA under an EUA for use by authorized laboratories. This test has been authorized only for detecting the presence of antibodies against SARS-CoV-2, not for any other viruses or pathogens. This test is only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of in vitro diagnostics for detection and/or diagnosis of COVID-19 under Section 564(b)(1) of the Act, 21 U.S.C. § 360bbb-3(b)(1), unless the authorization is terminated or revoked sooner. Product availability may vary by country.

The outcomes achieved by the Siemens Healthineers customers described herein were achieved in each customer’s unique setting. Since there is no “typical” hospital and many variables exist (e.g., hospital size, case mix, level of ITadoption) there can be no guarantee that others will achieve the same results.


The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.