Siemens Healthineers allergy testing key visual depicting a woman's face in teal tones with an artistic orange overlay on the right side

Making allergy testing routine

Consolidate your specialty, allergy, and general testing with one of the industry’s most reliable solutions

The prevalence of allergic diseases has continued to increase in the industrialized world for more than 50 years and worldwide sensitization rates to one or more common allergens among school children are approaching 40–50%.1 A clinical history of skin, gastrointestinal, or respiratory symptoms suggestive of allergy often leads to allergen-specific IgE testing.

The IMMULITE® 2000/2000XPi 3gAllergy™ Specific IgE assay helps to enhance patient care with reliable results from a simple blood test that uses quality extracts thoroughly evaluated for potency and allergenic composition.

With the IMMULITE 2000/2000XPi Immunoassay System, scaling your allergy and specialty test offerings feels routine.

3gAllergy Specific IgE assay components

Allergen-specific IgE assay components for IMMULITE 2000/2000 XPi

IMMULITE Allergy Wedge

  • Specific allergens and mixed allergen panels: When an allergic patient is tested, a reactive result may indicate a response to a specific allergen or a mix of allergens. Specific allergens and mixed allergen panels require the Universal Kit.
  • Universal Kit: All specific allergens and mixed allergen panels run with the Universal Kit to provide a result from the patient sample. One master curve applies to all specific allergens and mixed allergen panels.

Increase confidence in allergy results

The 3gAllergy Specific IgE assay uses third-generation chemiluminescent technology and proprietary liquid allergens that preserve their native conformational structure, maximizing binding and resulting in standardized, quantifiable results for informed decision making.

3gAllergy Specific IgE assay sequence

3gAllergy assay sequence 1 of 4

Serum and liquid-specific allergens incubate with anti-ligand-coated polystyrene bead.

3gAllergy assay sequence 2 of 4

Ligand-labeled liquid allergens bind to serum IgE antibodies and to the anti-ligand-coated bead.

3gAllergy assay sequence 3 of 4

Alkaline phosphatase-conjugated monoclonal anti-IgE is added and binds to serum IgE.

3gAllergy assay sequence 4 of 4

A chemiluminescent substrate is added, and light is emitted to provide a quantitative IgE result.

Improve operational efficiency

Improve productivity with a patented, high-capacity allergen wedge

Each allergen wedge can be customized with up to six user-defined, bar-coded allergen vials. As many as 23 wedges plus a universal reagent wedge fit on each carousel, for a total capacity of up to 138 allergens onboard at any time and a total of 5520 test capacity.

Minimize waste and eliminate errors

Reagent onboard stability of 90 days minimizes waste. Bar-coded allergens eliminate errors. All allergen information is scanned from the wedge.

Extensive allergy menu

Extensive menu of ~320 allergens, panels, and components across animals, drugs, dust, foods, grasses, insects, mites, molds, occupational, parasites, trees, and weeds. 

Educational resources

Each year in June, the World Allergy Organization (WAO) raises awareness about allergic diseases and their impact through the World Allergy Week initiative. We are committed to the care of allergic patients and WAO’s initiative to raise awareness by providing a variety of resources to help keep you informed of the latest topics in allergy diagnosis and testing.


CCDs and their relevance to in vitro allergy diagnostics

Webinar: Cross-reactive carbohydrate determinants and their relevance to in vitro allergy diagnostics

Join Dr. Friedrich Altmann as he discusses the different types of glycosylations, their relevance in allergy, and the impact of CCDs on liquid- and solid-phase in vitro diagnostic technologies for allergy.


Diagnostic approaches to determining food allergy versus food sensitivity/intolerance

Webinar: Diagnostic approaches to determining food allergy versus food sensitivity/intolerance

Join Dr. Erwin Gelfand as he discusses different diagnostic approaches to confirm food allergies and differentiate them from food sensitivity/intolerance.


Allergy Basics-Mechanisms of Disease and Testing Options

Webinar: Allergy basics—mechanisms of disease and testing options

Join Dr. Jim Aguanno, an expert in allergic diseases, as he reviews the mechanisms of allergic disease, and the importance of and need for allergy testing.


Cross-reactive carbohydrate determinants — history and relevance in allergy diagnostics

MLO article: Cross-reactive carbohydrate determinants — history and relevance in allergy diagnostics

MLO: The story of cross-reactive carbohydrate determinants (CCDs) is a fascinating journey that spans over 30 years of research and takes us on a global adventure.


Allergy testing literature compendium

Literature Compendium: Allergy Testing

A selection of published studies on the clinical utility of allergy diagnostic testing with a focus on IMMULITE 3gAllergy Specific IgE assays, including comparison to other in vivo and in vitro allergy tests.


Allergen component testing whitepaper

White Paper: Allergen Component Testing

Allergen component testing is a valuable diagnostic tool, as it allows clinicians to provide better differential diagnosis than allergen extract testing alone.

Predicting peanut allergy clinical brief

Clinical Brief: Predicting Peanut Allergy in an Unbiased Allergy Clinic Population Using Peanut-specific IgE Levels Measured in Two Independent Assays

This clinical brief describes research findings from a prospective cohort study conducted at the National Jewish Health hospital in Denver, Colorado.


Allergy menu

Allergy test menu

Extensive menu of ~500 allergens, panels, and components across animals, drugs, dust, foods, grasses, insects, mites, molds, occupational, parasites, trees, and weeds.

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