ADVIA Centaur XPT Immunoassay System
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ADVIA Centaur XPT Immunoassay System
 
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Designed with one of the most advanced software packages on the market, the ADVIA Centaur® XPT System is among the highest-throughput systems available. The ADVIA Centaur XPT System delivers the results that clinicians depend upon for accurate diagnoses and better patient care—and does so predictably and consistently.
Siemens unites innovative workflow solutions with clinical excellence in the ADVIA Centaur XPT System, leading to greater laboratory productivity to stay ahead of increasing workload demands.

ADVIA Centaur XPT Immunoassay System

ADVIA Centaur XPT Immunoassay System

ADVIA Centaur XPT Immunoassay System

ADVIA Centaur XPT Immunoassay System

Features & Benefits

Simplified, continuous operation

  • Intuitive, icon-driven user interface for simplified training and operation
  • On-the-fly loading and unloading of samples, reagents, and supplies
  • 2D bar-code scanner uploads test definitions with one easy scan, saving valuable time
  • Automated daily maintenance and no monthly cleaning procedures
  • No daily startup procedure
  • Status light displays system alerts visible from anywhere in the laboratory


Accurate, timely results

  • Comprehensive menu supports over 70 tests*
  • Versatile, advanced AE technology, with over 40 active patents, enables continual introduction of new and innovative assays
  • Up to 240 tests per hour for fast turnaround, even during peak workload times
  • STAT port allows priority sampling at any time, even when connected to automation
  • Highly stable, ready-to-use reagents are used on all ADVIA Centaur systems
  • Disposable sample tips ensure no sample-to-sample carryover
  • Automated clot management virtually eliminates operator intervention
  • SMART algorithm software automates repeat and confirmatory testing of reactive samples


Powerful, seamless connectivity

  • Designed for automation; requires no additional robotics
  • Point-in-space technology enables direct-from-track sampling
  • STAT samples can be front-loaded at any time for immediate sampling, driving rapid turnaround time (TAT)
  • Direct connectivity to Siemens Automation Solutions, the CentraLink™ Data Management System, and Siemens Remote Service (SRS) , enabling laboratories to adapt and grow as their workloads demand

 

Assays

Anemia
Active B12
Ferritin
Folate
RBC Folate
Vitamin B12

 

Autoimmune
Anti-CCP

 

Bone Metabolism
Intact PTH
Vitamin D Total

 

Cardiac
BNP
CKMB
High-Sensitivity Troponin I (TNIH)
Myoglobin
TnI-Ultra™

 

Diabetes
C-Peptide
Insulin

 

Hepatitis
Anti-HBs2
HAV IgM
HAV Total
HBc IgM
HBc Total
HBe Ag
HBs Ag Confirmatory
HBs AgII
HCV***
 

HIV
HIV 1/O/2 Enhanced (EHIV)§
HIV Combo§


Immunosuppressant Drugs
Cyclosporine
Everolimus**
Tacrolimus**

Inflammation
IgE, Total
 

Metabolic
Cortisol
Homocysteine


 

Oncology
AFP
BR 27.29
CA 125II
CA 15-3
CA 19-9
Calcitonin
CEA
Complexed PSA
PSA
Serum HER-2/neu

 

Reproductive Endocrinology
AFP
Anti-Müllerian Hormone**
DHEAS
Enhanced Estradiol
Free βhCG‡‡
FSH
hCG
LH
PAPP-A‡‡
PlGF**
Progesterone
Prolactin
sFLT-1**
SHBG
Testosterone II

 

Special ID
EBV-EBNA IgG**
EBV-VCA IgG**
EBV-VCA IgM**
Syphilis
Zika IgM††

 

Therapeutic Drug Monitoring (TDM)
Carbamazepine
Digitoxin
Digoxin
Gentamicin
Phenobarbital
Phenytoin
Theophylline
Valproic Acid
Vancomycin

 

Thyroid
Anti-TG
Anti-TPO
Free T3
Free T4
T Uptake
Total T3
Total T4
TSH3-Ultra
TSH

 

ToRCH
CMV IgG
CMV IgM**
Herpes-1 IgG
Herpes-2 IgG
Rubella IgG
Rubella IgM
Toxoplasma IgG
Toxoplasma IgM

Technical Specifications

Product Specifications
System DescriptionRandom-access immunoassay system
Test ThroughputUp to 240 tests per hour
Time to First Result18 minutes; results every 15 seconds thereafter, assay dependent
Assays Onboard30 assays
Disease-State Assay GroupsAllergy, Anemia/Iron Metabolism, Bone Metabolism, Cardiac, Diabetes, Hepatitis, Immunosuppressant Drugs, Metabolic, Oncology, Reproductive Endocrinology, Special ID, Therapeutic Drug Monitoring (TDM), Thyroid, ToRCH
Continuous OperationLoading/unloading of samples and consumables at any time without interrupting system operation. Includes sample racks, STATs, reagent packs, ancillary reagent packs, reaction cuvettes, sample pipette tips, calibrators, controls, wash fluids, water, and waste.

 

Sample Handling
Sample Tubes3 mL, 5 mL, 7 mL, and 10 mL tubes; 1 mL and 2 mL sample cups; microcontainer tubes
Sample InputUniversal 5-position rack holds multiple tube types; 180 samples fully loaded; no-pause loading and unloading
Validated Sample TypesSerum, plasma, urine (assay-dependent)
Sample Volume per Test10–200 μL, assay-dependent
Sample Integrity ControlPressure transducer technology with clot detection, flagging, and management; short-sample detection
STAT HandlingDedicated STAT port accepts samples any time; STAT samples are processed with priority
Auto-repeatUser-definable
Sample DilutionAutomatic dilution varies by assay, up to 1:2500
Auto-reflex TestingAutomatic ability to perform additional tests based on results of first test
Sample Pipette Tips840 disposable sample tip capacity
Sample Carryover PreventionDisposable pipette tips ensure zero sample carryover

 

Bar Codes
Sample Bar CodesUp to 20 digits; Interleaved 2 of 5; Code 39, Code 128, Codabar; A, B, and special characters (.-+/*$%)

 

Reaction Area
Reaction CuvettesCapacity of 1000 optical-grade plastic cuvettes
Reaction BathAir bath, 37°C
Assay Result CalculationsSMART algorithm software repeats and confirms reactive testing; results available as completed
Assay TechnologyChemiluminescence using Advanced Acridinium Ester

 

Reagent Handling
Reagent Tray30-position reagent tray refrigerated between 4 and 10°C (39–50°F)
Reagent Capacity Onboard30 assays
Reagent ContainersADVIA Centaur® ReadyPack® (various pack sizes available)
Reagent Integrity ControlBar-code reagent identification, automatic inventory tracking and flagging, calibration valid tracking and flagging, reagent onboard stability tracking and flagging, reagent expired/reagent low flagging
Onboard Stability28 days (average)
Reagent MixingADVIA Centaur ReadyPacks automatically rocked onboard
Ancillary Reagents25-position ancillary reagent tray cooled 4–8°C (39–46°F)

 

Calibration/QC
Auto-calibration/Auto-QCAvailable automatic QC ordering by test, control, date, and time
QC DataAdvanced QC package includes Levey-Jennings plots and Westgard rules


User Interface/Data Management
Monitor22-inch diagonal high-resolution LCD touchscreen with adjustable height
Operating SystemMicrosoft® Windows® 7
System DocumentationOperator manual, quickstart guide, and context-sensitive online help
Data Storage1,000,000 test/QC results; 500,000 can be historical; can archive to removable media
Onboard Maintenance LogsYes
Host InterfaceRS232C bidirectional and host query; Ethernet connection available
Host QueryYes
Remote Access & Service1000Base-T Ethernet port for remote access and modem for Siemens Remote Service

 

Removable Media
Removable MediaCD, DVD, or USB

 

General Specifications
Power Requirements200-240 V at 50/60 Hz; 1.2 kW maximum
Maximum Water Consumption2.5 liters (0.6 gallons) per hour
Drain RequirementsMinimum of 2.5 liters (0.6 gallons) per hour
DimensionsWith monitor: 167 (h) x 196 (w) x 104 (d) cm; 66 (h) x 77 (w) x 41 (d) in.
Without monitor: 133 (h) x 196 (w) x 104 (d) cm; 52 (h) x 77 (w) x 41 (d) in.
Weight585 kg (1289 lb)
ComplianceComplies with international environmental, health, and safety standards
Noise Emission65 dB maximum
Processing Heat Output5100 BTU/hour
Ambient Temperature18–30°C (64–86°F)
Ambient Humidity20–80% noncondensing
Floor Load-Bearing Requirement412 kg/m2 (84 lb/ft2)

 


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*Assay availability varies
** Under development. Not available for sale.
Not available for sale in the U.S.
CA 125II is a trademark of Fujirebio Diagnostics, Inc.
§ Assay developed, manufactured, and sold by Siemens Healthcare Diagnostics Inc. for Ortho Clinical Diagnostics, Inc. and Grifols Diagnostic Solutions Inc.
*** For outside of the U.S. only, assay developed, manufactured, and sold by Siemens Healthcare Diagnostics Inc. for Ortho Clinical Diagnostics, Inc. and Grifols Diagnostic Solutions Inc.

†† The ADVIA Centaur Zika Test has not been FDA cleared or approved. This test has been authorized by FDA under an EUA for use by authorized laboratories. This test has been authorized only for the diagnosis for Zika virus infection and not for any other viruses or pathogens. This test is only authorized for the duration of the declaration that circumstances exist justifying the authorization of the emergency use of in vitro diagnostic tests for detection of Zika virus and/or diagnosis of Zika virus infection under section 564(b)(1) of the Act, 21 U.S.C. § 360bbb-3(b)(1), unless the authorization is terminated or revoked sooner
‡‡ For Research Use Only in the U.S. Not for use in clinical or diagnostic procedures in the U.S.