ADVIA Chemistry XPT System
An advanced automated clinical chemistry analyzer for high-volume laboratories

ADVIA Chemistry XPT System
 
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The ADVIA® Chemistry XPT System provides timely, reliable results with continuous operation to meet the chemistry workloads of the most demanding laboratories.

ADVIA Chemistry XPT System

ADVIA Chemistry XPT System

Chemistry analyzer connected to automation

Automation-ready

Increase productivity with high throughput of up to 2400 tests per hour and seamless connectivity to Siemens Healthineers automation solutions.

VeriSmart Technology Onboard

Improve turnaround time and accuracy of results with the unique combination of VeriSmart® Technology, micro-volume technology, and aliquot retention.
Easy-to-use software

Simplify Operations

Simplify operations with intuitive software for comprehensive management of data and system functions, including advanced reporting capabilities.
Uninterrupted Processing

Uninterrupted Processing

Enhance efficiency through uninterrupted processing when loading and unloading most system fluids.

Features & Benefits

The ADVIA® Chemistry XPT System*** is engineered for continuous operation and timely, accurate results—supporting you to reach your full potential today and be prepared for tomorrow. With an advanced user interface that is easy to use and VeriSmart® Technology to support accuracy of testing, the ADVIA Chemistry XPT System predictably and consistently delivers timely, reliable results to meet expanding workloads.

 

Simplified, continuous operation

  • Intuitive, icon-driven user interface for simplified training and operation
  • ISE module designed for high throughput without the need for routine maintenance
  • Concentrated reagents provide a high number of tests onboard for long walkaway times
  • Status light displays system alerts visible from anywhere in the laboratory
  • On-the-fly loading of most system fluids
  • Automated short maintenance washes and procedures
  • Maintenance-free reaction bath and optical system
  • Automated calibration, QC, startup, and shutdown
     

Seamless connectivity to powerful automation and diagnostics IT

 

Consistent, predictable turnaround time and timely, accurate results

  • Comprehensive menu of 116 assays (June 2014); supports up to 2400 tests per hour (1800 photometric plus 600 ISE) to provide consistent and predictable TAT
  • Micro-volume technology reduces blood-draw requirements by using a single 30 μL sample for up to 15 tests
  • Quick release of sample tubes allows parallel tube processing and rapid, predictable TAT
  • Aliquot retention allows automated, preprogrammable dilution, reflex, and rerun testing without calling back the sample
  • STAT and specialty samples can always be front-loaded while the track is running
  • Sample integrity checks, including hemolysis, icterus, lipemia, and clot detection, are performed without operator intervention while maintaining high throughput

 

Assays

Diabetes 

Fructosamine
Hemoglobin A1c (Enzymatic)


Drugs of Abuse/Toxicology

6-Acetylmorphine (6-AM)*
Acetaminophen
Amphetamines
Barbiturates, Urine
Barbiturates, Serum
Benzodiazepines, Urine
Benzodiazepines, Serum
Buprenorphine*
Cannabinoids (THC)
Cocaine Metabolite
Ecstasy
Ethyl Alcohol
Methadone
Methadone Metabolites
Opiates
Oxycodone*
Phencyclidine
Propoxyphene
Salicylate
Tricyclic Antidepressants

General Chemistry

Alanine Aminotransferase
Alanine Aminotransferase (P5P)
Albumin (BCG)†,‡
Albumin (BCP)
Alkaline Phosphatase (AMP)§
Alkaline Phosphatase (DEA)**
Ammonia
Amylase
Aspartate Aminotransferase
Aspartate Aminotransferase (P5P)
Bilirubin, Direct
Bilirubin, Total
Calcium (Arsenazo)
Calcium (CPC)
Carbon Dioxide (Enzymatic)§
Chloride
Cholesterol
Cholinesterase
Creatine Kinase
Creatinine
Creatinine (Enzymatic)
Gamma-Glutamyltransferase (GGT)
Glucose (Hexokinase)
Glucose (Oxidase)
HDL Cholesterol
Iron
Lactate
Lactate Dehydrogenase (L-P)
Lactate Dehydrogenase (P-L)
LDL Cholesterol
Lipase
Magnesium
Microalbumin
Pancreatic Amylase
Phosphorus
Potassium
Sodium
Total Iron Binding Capacity (TIBC)
Total Protein
Total Protein, CSF/Urine
Triglycerides
Urea Nitrogen (BUN)
Uric Acid

Specific Proteins

α1-Acid Glycoprotein
α1-Antitrypsin
Antistreptolysin O
Apolipoprotein A1
Apolipoprotein B
β-2 Microglobulin
Complement C3
Complement C4
CRP
CRP, High Sensitivity
CRP, Wide Range
Cystatin C
Ferritin
Haptoglobin
Immunoglobulin A
Immunoglobulin G
Immunoglobulin M
Lipoprotein(a)
Myoglobin
Prealbumin
Rheumatoid Factor
Soluble Transferrin Receptor (sTfR)**,††,‡‡
Transferrin
 

Therapeutic Drug Monitoring

Carbamazepine
Digoxin
Gentamicin
Lithium
Methotrexate††,‡‡
Phenobarbital
Phenytoin
Theophylline
Tobramycin
Valproic Acid
Vancomycin
 

Validity Testing

Creatinine††,§§
Nitrite††,§§
Oxidant††,§§
pH††,§§
Specific Gravity††,§§

Technical Specifications

Product Specifications 
System DescriptionFully random and continuous access, discrete processing clinical chemistry system with batch run capability
Test ThroughputUp to 2400 tests/hour: 1800 tests/hour photometric, 600 tests/hour ISE
Assays Onboard59 assays, including 3 ISE (Na, K, Cl)
Sample Handling
Sample Tubes5 mL, 7 mL, and 10 mL tubes; 1 mL and 2 mL sample cups; user-defined containers
Sample Tray84 sample positions; positive sample identification
Validated Sample TypesSerum, plasma, urine, whole blood, and CSF, assay-dependent
Sample Integrity ControlQualitative check for hemolysis, lipemia, and icterus; clot detection, flagging, and management; short-sample detection, flagging, and management
STAT Handling84 positions, not dedicated; STAT samples are processed with priority
Auto-repeat TestingAutomatic repeat testing from the retained prediluted sample or original sample
Sample DilutionAutomatic dilution up to 1:5625 from retained prediluted sample or original sample
Auto-reflex TestingAutomatic ability to perform additional tests based on results of first test or test combination
Primary Sample ProbeLiquid-level sensing, crash protection, clot/clog detection, liquid-surface verification
Sample Carryover PreventionAutomated wash; additional automated sample probe washes programmable for greater prevention
Sample ThroughputUp to 200 tubes per hour with ISE use; faster without ISE use
Bar Codes  
Sample Bar CodesUp to 20 digits; Interleaved 2 of 5, Code 39, Code 128, Codabar; A, B, and special characters (.-+/*$%)
Micro-volume Technology  
Automatic Sample PredilutionSamples typically diluted 1:5 (30 μL sample + 120 μL saline generates up to 15 tests results); retained for auto-repeat, auto-reflex, or auto-dilution until results are available
Predilution Tray120 dilution cuvettes
Sample Volume per Test2–30 μL of prediluted sample, equating to 0.4–6.0 μL of original sample per test (varies by assay)
Average Reagent Volume80–120 μL per test, assay-dependent
Reaction Area  
Reaction Cuvettes340 reusable optical-grade plastic cuvettes
Reaction BathInert fluorocarbon oil circulation system, 37°C
Photometer14 fixed wavelengths (340, 410, 451, 478, 505, 545, 571, 596, 658, 694, 751, 805, 845, and 884 nm)
Light Source12V, 50W halogen lamp, cooled by forced water circulation
Assay Result CalculationsEndpoint (EPA), rate reaction (RRA), 2-point rate (2PA), constant rate analysis (CRA), and immunoassay analysis (IMA) methodologies; prozone checking; substrate depletion check; results available as completed
Reaction Times3, 4, 5, and 10 minutes; extended reaction times 15 and 21 minutes
Automatic CorrectionSample blank, cuvette blank, measurement point change, sample volume change in re-assay
Point ForwardingCan automatically extend linearity to measure samples over assay range
Assay TechnologyPotentiometric, photometric, turbidimetric
Reagent Handling  
Reagent Tray2 trays, (R1=60 and R2 =56 positions), refrigerated between 6°C and 13°C (43°F–55°F)
Reagent Capacity Onboard56 photometric assays
Test Capacity Onboard40,000 photometric tests average; over 100,000 photometric tests with the use of concentrated reagents
Reagent Containers20, 40, 70 mL reagent wedges
Reagent Integrity ControlBar-code reagent identification; automatic inventory tracking and flagging; calibration and control validity tracking and flagging; reagent onboard stability tracking and flagging; reagent expired/reagent low flagging
Onboard StabilityUp to 60 days, depending on assay
Reagent DilutionsCapability to dilute concentrated reagents onboard
Open-system Capability  
Channels200 assay channels; includes 50 channels for user-defined applications
Ion-selective Electrodes (ISE)  
ISEIndirect simultaneous measurement of Na+, K+, Cl-
ISE Sample Volume22 μL original sample for all three tests
Electrode Expected Use Life30,000 samples or 3 months, whichever occurs first
Throughput RateUp to 600 tests/hour; 200 tubes/hour
Calibration/QC  
Validated Calibration IntervalUp to 60 days, tracked by software
Auto-calibrationUser-defined time interval or with new reagent container
Auto-QCUser-defined test count interval or with auto-calibration
View CalibrationGraphical display of calibration curves
QC DataGraphical display of QC; real-time/QC monitoring; Advanced QC package includes Levey-Jennings plots, Westgard rules, and RiliBÄK rules; 125,000 control results can be stored, archivable to removable media
Calibration/Control Tray61 refrigerated positions for calibrators, controls, and diluents
User Interface/Data Management  
Monitor22-inch (55.9 cm) diagonal high-resolution LCD touchscreen with adjustable height
Operating SystemMicrosoft® Windows® 7
System DocumentationOperator manual, quickstart guide, and online help
Data Storage500,000 active plus 500,000 historical test results; can archive to removable media
Onboard Maintenance LogsYes
Host InterfaceTCP/IP bidirectional
Host QueryASTM; system requests work order or batch of work orders from host
Remote Access and ServiceSiemens Remote Service via 1000BASE-T Ethernet port
Removable Media  
Removable MediaDVD, CD-RW, or USB
General Specifications  
Power Requirements200–240V at 50/60 Hz, 3 kVA consumption
Water RequirementsCLSI® Clinical Laboratory Reagent Water or equivalent connected directly to a pressurized water source
Maximum Water Consumption40 liters (10.6 gallons) per hour
Drain RequirementsMinimum of 40 liters (10.6 gallons) per hour
DimensionsWith monitor: 149 (h) x 177 (w) x 99 (d) cm; 59 (h) x 70 (w) x 39 (d) inches
Without monitor: 134 (h) x 177 (w) x 99 (d) cm; 53 (h) x 70 (w) x 39 (d) inches
Weight725 kg (1598 lb)
ComplianceComplies with international environmental, health, and safety standards, including CE and RoHS
Noise EmissionLess than 62 dB
Processing Heat Output5374 BTU/hour
Ambient Temperature18°–30°C (64°-86°F)
Ambient Humidity20–80% noncondensing

 


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Related Products, Services & Resources

* Alliance Application manufactured and distributed by Siemens Healthcare Diagnostics.
Also available in concentrated version.
ADVIA Chemistry XPT System supports concentrated version only.
§ Available only in concentrated version.
** Not available for sale in the U.S.
†† Not currently available on the ADVIA Chemistry XPT System.
‡‡ Alliance Application manufactured by third party, distributed by Siemens Healthcare Diagnostics.
§§ Syva application. Restricted in the U.S. to law enforcement-related use (forensic use only).

***Due to local regulations, not all products are available in all countries.

Product availability may vary from country to country and is subject to varying regulatory requirements. Please contact your local representative for availability.

The outcomes achieved by the Siemens Healthineers customers described herein were achieved in each customer’s unique setting. Since there is no “typical” hospital and many variables exist (e.g., hospital size, case mix, level of IT adoption) there can be no guarantee that others will achieve the same results.