ADVIA Chemistry XPT System
An advanced automated clinical chemistry analyzer for high-volume laboratories
The ADVIA® Chemistry XPT System provides timely, reliable results with continuous operation to meet the chemistry workloads of the most demanding laboratories.
- Delivers high throughput of up to 2400 tests per hour.
- Manages comprehensive testing with a menu of more than 115 assays.
- Improves workflow using automation and system technologies such as micro-volume and aliquot retention.
ADVIA Chemistry XPT System
Automation-ready
VeriSmart Technology Onboard
Simplify Operations
Uninterrupted Processing
Features & Benefits
The ADVIA® Chemistry XPT System*** is engineered for continuous operation and timely, accurate results—supporting you to reach your full potential today and be prepared for tomorrow. With an advanced user interface that is easy to use and VeriSmart® Technology to support accuracy of testing, the ADVIA Chemistry XPT System predictably and consistently delivers timely, reliable results to meet expanding workloads.
Simplified, continuous operation
- Intuitive, icon-driven user interface for simplified training and operation
- ISE module designed for high throughput without the need for routine maintenance
- Concentrated reagents provide a high number of tests onboard for long walkaway times
- Status light displays system alerts visible from anywhere in the laboratory
- On-the-fly loading of most system fluids
- Automated short maintenance washes and procedures
- Maintenance-free reaction bath and optical system
- Automated calibration, QC, startup, and shutdown
Seamless connectivity to powerful automation and diagnostics IT
- Designed for automation; requires no additional robotics
- Point-in-space technology enables direct-from-track sampling
- Onboard aliquotting allows sample to be immediately released to the next workstation, driving productivity and improving laboratory turnaround time (TAT)
- Direct connectivity to Siemens Aptio Automation Solutions, ADVIA Automation Solutions, the CentraLink™ Data Management System, and Siemens Remote Service (SRS), enable laboratories to adapt and grow as their workloads demand
Consistent, predictable turnaround time and timely, accurate results
- Comprehensive menu of 116 assays (June 2014); supports up to 2400 tests per hour (1800 photometric plus 600 ISE) to provide consistent and predictable TAT
- Micro-volume technology reduces blood-draw requirements by using a single 30 μL sample for up to 15 tests
- Quick release of sample tubes allows parallel tube processing and rapid, predictable TAT
- Aliquot retention allows automated, preprogrammable dilution, reflex, and rerun testing without calling back the sample
- STAT and specialty samples can always be front-loaded while the track is running
- Sample integrity checks, including hemolysis, icterus, lipemia, and clot detection, are performed without operator intervention while maintaining high throughput
Assays
Diabetes
Fructosamine
Hemoglobin A1c (Enzymatic)
Drugs of Abuse/Toxicology
6-Acetylmorphine (6-AM)*
Acetaminophen
Amphetamines
Barbiturates, Urine
Barbiturates, Serum
Benzodiazepines, Urine
Benzodiazepines, Serum
Buprenorphine*
Cannabinoids (THC)
Cocaine Metabolite
Ecstasy
Ethyl Alcohol
Methadone
Methadone Metabolites
Opiates
Oxycodone*
Phencyclidine
Propoxyphene
Salicylate
Tricyclic Antidepressants
General Chemistry
Alanine Aminotransferase†
Alanine Aminotransferase (P5P)†
Albumin (BCG)†,‡
Albumin (BCP)
Alkaline Phosphatase (AMP)§
Alkaline Phosphatase (DEA)**
Ammonia
Amylase
Aspartate Aminotransferase†
Aspartate Aminotransferase (P5P)†
Bilirubin, Direct
Bilirubin, Total
Calcium (Arsenazo)†
Calcium (CPC)†
Carbon Dioxide (Enzymatic)§
Chloride
Cholesterol†
Cholinesterase
Creatine Kinase
Creatinine†
Creatinine (Enzymatic)
Gamma-Glutamyltransferase (GGT)
Glucose (Hexokinase)†
Glucose (Oxidase)†
HDL Cholesterol
Iron
Lactate
Lactate Dehydrogenase (L-P)
Lactate Dehydrogenase (P-L)
LDL Cholesterol
Lipase
Magnesium†
Microalbumin
Pancreatic Amylase
Phosphorus†
Potassium
Sodium
Total Iron Binding Capacity (TIBC)
Total Protein†
Total Protein, CSF/Urine
Triglycerides†
Urea Nitrogen (BUN)†
Uric Acid†
Specific Proteins
α1-Acid Glycoprotein
α1-Antitrypsin
Antistreptolysin O
Apolipoprotein A1
Apolipoprotein B
β-2 Microglobulin
Complement C3
Complement C4
CRP
CRP, High Sensitivity
CRP, Wide Range
Cystatin C
Ferritin
Haptoglobin
Immunoglobulin A
Immunoglobulin G
Immunoglobulin M
Lipoprotein(a)
Myoglobin
Prealbumin
Rheumatoid Factor
Soluble Transferrin Receptor (sTfR)**,††,‡‡
Transferrin
Therapeutic Drug Monitoring
Carbamazepine
Digoxin
Gentamicin
Lithium
Methotrexate††,‡‡
Phenobarbital
Phenytoin
Theophylline
Tobramycin
Valproic Acid
Vancomycin
Validity Testing
Creatinine††,§§
Nitrite††,§§
Oxidant††,§§
pH††,§§
Specific Gravity††,§§
Technical Specifications
| Product Specifications | |
|---|---|
| System Description | Fully random and continuous access, discrete processing clinical chemistry system with batch run capability |
| Test Throughput | Up to 2400 tests/hour: 1800 tests/hour photometric, 600 tests/hour ISE |
| Assays Onboard | 59 assays, including 3 ISE (Na, K, Cl) |
| Sample Handling | |
| Sample Tubes | 5 mL, 7 mL, and 10 mL tubes; 1 mL and 2 mL sample cups; user-defined containers |
| Sample Tray | 84 sample positions; positive sample identification |
| Validated Sample Types | Serum, plasma, urine, whole blood, and CSF, assay-dependent |
| Sample Integrity Control | Qualitative check for hemolysis, lipemia, and icterus; clot detection, flagging, and management; short-sample detection, flagging, and management |
| STAT Handling | 84 positions, not dedicated; STAT samples are processed with priority |
| Auto-repeat Testing | Automatic repeat testing from the retained prediluted sample or original sample |
| Sample Dilution | Automatic dilution up to 1:5625 from retained prediluted sample or original sample |
| Auto-reflex Testing | Automatic ability to perform additional tests based on results of first test or test combination |
| Primary Sample Probe | Liquid-level sensing, crash protection, clot/clog detection, liquid-surface verification |
| Sample Carryover Prevention | Automated wash; additional automated sample probe washes programmable for greater prevention |
| Sample Throughput | Up to 200 tubes per hour with ISE use; faster without ISE use |
| Bar Codes | |
| Sample Bar Codes | Up to 20 digits; Interleaved 2 of 5, Code 39, Code 128, Codabar; A, B, and special characters (.-+/*$%) |
| Micro-volume Technology | |
| Automatic Sample Predilution | Samples typically diluted 1:5 (30 μL sample + 120 μL saline generates up to 15 tests results); retained for auto-repeat, auto-reflex, or auto-dilution until results are available |
| Predilution Tray | 120 dilution cuvettes |
| Sample Volume per Test | 2–30 μL of prediluted sample, equating to 0.4–6.0 μL of original sample per test (varies by assay) |
| Average Reagent Volume | 80–120 μL per test, assay-dependent |
| Reaction Area | |
| Reaction Cuvettes | 340 reusable optical-grade plastic cuvettes |
| Reaction Bath | Inert fluorocarbon oil circulation system, 37°C |
| Photometer | 14 fixed wavelengths (340, 410, 451, 478, 505, 545, 571, 596, 658, 694, 751, 805, 845, and 884 nm) |
| Light Source | 12V, 50W halogen lamp, cooled by forced water circulation |
| Assay Result Calculations | Endpoint (EPA), rate reaction (RRA), 2-point rate (2PA), constant rate analysis (CRA), and immunoassay analysis (IMA) methodologies; prozone checking; substrate depletion check; results available as completed |
| Reaction Times | 3, 4, 5, and 10 minutes; extended reaction times 15 and 21 minutes |
| Automatic Correction | Sample blank, cuvette blank, measurement point change, sample volume change in re-assay |
| Point Forwarding | Can automatically extend linearity to measure samples over assay range |
| Assay Technology | Potentiometric, photometric, turbidimetric |
| Reagent Handling | |
| Reagent Tray | 2 trays, (R1=60 and R2 =56 positions), refrigerated between 6°C and 13°C (43°F–55°F) |
| Reagent Capacity Onboard | 56 photometric assays |
| Test Capacity Onboard | 40,000 photometric tests average; over 100,000 photometric tests with the use of concentrated reagents |
| Reagent Containers | 20, 40, 70 mL reagent wedges |
| Reagent Integrity Control | Bar-code reagent identification; automatic inventory tracking and flagging; calibration and control validity tracking and flagging; reagent onboard stability tracking and flagging; reagent expired/reagent low flagging |
| Onboard Stability | Up to 60 days, depending on assay |
| Reagent Dilutions | Capability to dilute concentrated reagents onboard |
| Open-system Capability | |
| Channels | 200 assay channels; includes 50 channels for user-defined applications |
| Ion-selective Electrodes (ISE) | |
| ISE | Indirect simultaneous measurement of Na+, K+, Cl- |
| ISE Sample Volume | 22 μL original sample for all three tests |
| Electrode Expected Use Life | 30,000 samples or 3 months, whichever occurs first |
| Throughput Rate | Up to 600 tests/hour; 200 tubes/hour |
| Calibration/QC | |
| Validated Calibration Interval | Up to 60 days, tracked by software |
| Auto-calibration | User-defined time interval or with new reagent container |
| Auto-QC | User-defined test count interval or with auto-calibration |
| View Calibration | Graphical display of calibration curves |
| QC Data | Graphical display of QC; real-time/QC monitoring; Advanced QC package includes Levey-Jennings plots, Westgard rules, and RiliBÄK rules; 125,000 control results can be stored, archivable to removable media |
| Calibration/Control Tray | 61 refrigerated positions for calibrators, controls, and diluents |
| User Interface/Data Management | |
| Monitor | 22-inch (55.9 cm) diagonal high-resolution LCD touchscreen with adjustable height |
| Operating System | Microsoft® Windows® 7 |
| System Documentation | Operator manual, quickstart guide, and online help |
| Data Storage | 500,000 active plus 500,000 historical test results; can archive to removable media |
| Onboard Maintenance Logs | Yes |
| Host Interface | TCP/IP bidirectional |
| Host Query | ASTM; system requests work order or batch of work orders from host |
| Remote Access and Service | Siemens Remote Service via 1000BASE-T Ethernet port |
| Removable Media | |
| Removable Media | DVD, CD-RW, or USB |
| General Specifications | |
| Power Requirements | 200–240V at 50/60 Hz, 3 kVA consumption |
| Water Requirements | CLSI® Clinical Laboratory Reagent Water or equivalent connected directly to a pressurized water source |
| Maximum Water Consumption | 40 liters (10.6 gallons) per hour |
| Drain Requirements | Minimum of 40 liters (10.6 gallons) per hour |
| Dimensions | With monitor: 149 (h) x 177 (w) x 99 (d) cm; 59 (h) x 70 (w) x 39 (d) inches Without monitor: 134 (h) x 177 (w) x 99 (d) cm; 53 (h) x 70 (w) x 39 (d) inches |
| Weight | 725 kg (1598 lb) |
| Compliance | Complies with international environmental, health, and safety standards, including CE and RoHS |
| Noise Emission | Less than 62 dB |
| Processing Heat Output | 5374 BTU/hour |
| Ambient Temperature | 18°–30°C (64°-86°F) |
| Ambient Humidity | 20–80% noncondensing |
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Related Products, Services & Resources
* Alliance Application manufactured and distributed by Siemens Healthcare Diagnostics.
† Also available in concentrated version.
‡ ADVIA Chemistry XPT System supports concentrated version only.
§ Available only in concentrated version.
** Not available for sale in the U.S.
†† Not currently available on the ADVIA Chemistry XPT System.
‡‡ Alliance Application manufactured by third party, distributed by Siemens Healthcare Diagnostics.
§§ Syva application. Restricted in the U.S. to law enforcement-related use (forensic use only).
***Due to local regulations, not all products are available in all countries.
Product availability may vary from country to country and is subject to varying regulatory requirements. Please contact your local representative for availability.
The outcomes achieved by the Siemens Healthineers customers described herein were achieved in each customer’s unique setting. Since there is no “typical” hospital and many variables exist (e.g., hospital size, case mix, level of IT adoption) there can be no guarantee that others will achieve the same results.