NATIVE (Non-contrast MRA of ArTerIes and VEins) is a contrast-free MR angiography technique for visualizing the vessels of the body. The package contains protocols tailored for use in different body regions (e.g. renal arteries, peripheral vessels). Inline Subtraction and Inline Maximum Intensity Projection (MIP) further simplify the workflow.


Clinical Applications

  • Alternative to contrast-enhanced MRA examinations when there is contraindication to use of Gadolinium.

Características y Beneficios

Additional Information

For non-contrast MR Angiography Siemens currently offers two techniques under the category of NATIVE — NATIVE TrueFISP and NATIVE SPACE. NATIVE TrueFISP is based on the TrueFISP (True Fast Imaging with Steady state Precession) sequence, which is a balanced steady state gradient echo technique. The contrast mechanism for NATIVE TrueFISP comes from the preparation of the imaging volume with a spatially selective inversion pulse, resulting in the suppression of stationary tissue within the imaging volume and suppression of signal from blood in the imaging volume (e.g. venous blood). Blood which flows into the imaging volume during the inversion time has the same high-signal characteristics exhibited in that TrueFISP. The contrast is further enhanced by the suppression of the background by the inversion pulse. The sequence can be made selective for arteries or veins by appropriate positioning of the inversion pulse, which can be positioned independently from the imaging volume. The sequence accommodates 3D, 2D, breath-hold, syngo PACE (Prospective Acquisition CorrEction) navigated and respiratory triggered approaches depending on clinical environment.


The NATIVE SPACE technique is a modified variable flip angle 3D Turbo Spin Echo sequence in which the contrast mechanism for visualizing vessels is based on the difference in intravascular signal between maximal and minimal flow during the cardiac cycle. The subtracted image is calculated Inline and with Inline MIP generation, instantaneous clinical results are produced for completely non-invasive MR angiography, further improving workflow at the scanner. The NATIVE SPACE technique can also accommodate multi-phase imaging that enables dynamic angiography — for example, in the lower legs.

General Requirements

  • Biograph mMR
  • MAGNETOM Espree
  • MAGNETOM Prisma
  • MAGNETOM Skyra
  • MAGNETOM Spectra
  • MAGNETOM Trio, A Tim System
  • MAGNETOM Verio
  • MAGNETOM Prismafit
  • MAGNETOM Skyrafit
  • MAGNETOM Avantofit
  • MAGNETOM Amira
  • MAGNETOM Sempra
  • MAGNETOM Symphony, A Tim System
  • MAGNETOM Avanto
  • MAGNETOM Solafit
  • MAGNETOM Vidafit
  • MAGNETOM Altea
  • MAGNETOM Lumina

syngo MR B17
syngo MR C15
syngo MR D11

Please Note: Additional technical pre-requisites may apply. Upon receiving your request, your local Siemens representative will clarify whether your system meets the requirements.