MR-only Radiotherapy Planning
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While MR provides excellent soft-tissue contrast and functional information, CT is still required for electron density information for accurate dose calculation. As a result, many institutions have to adapt their RT treatment planning workflow, in which patients are normally scanned on both imaging modalities. Fusing CT and MRI modalities makes the workflow more complicated and adds uncertainties in the planning process.1, 2
MR-based Synthetic CT offers the possibility of combining the superior soft-tissue contrast of MRI for organs-at-risk and target delineation with dosimetric planning. An MR-only workflow eliminates the need for CT to MRI registration, reducing systematic registration errors and unnecessary ionizing radiation from CT scans.
Discover our MR-only workflow for brain and pelvis.
Features & Benefits
MR-based Synthetic CT3
Enabling a straight forward MR-only workflow for RT planning with our AI-powered algorithm for pelvis and brain.
Courtesy of Universitätsklinikum Erlangen, Strahlenklinik, Germany
Challenges of combined MR and CT workflow
- Accurate image registration
- Patient scheduling
- Resource utilization & reimbursement
MR-based Synthetic CT results for pelvis and brain
Image examples brain
Image examples pelvis
The MR-only radiotherapy planning workflow typically encompasses five main areas
An internal validation of geometric fidelity and HU unit accuracy
For HU accuracy, line profiles from CT and MR-based Synthetic CT of the same patient were compared as shown in the image.
Clinical evaluation and image courtesy of Brigham & Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA
Dosimetric and position results in the pelvis
- <1% dose difference in the CTV and evaluated OARs
- 1%/2 mm gamma analysis agreement of 98.9 ± 0.3%
- Absolute differences in positioning with CBCT <1 mm
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The data acquisition protocols for MR-based Synthetic CT are available with syngo MR XA11A and later software versions with RT Pro edition for MAGNETOM Sola and Vida, with syngo XA30 and later software Versions for MAGNETOM Aera and MAGNETOM Skyra.
Compressed Sensing GRASP-VIBE for other regions than liver is not for sale in the U.S. Intended Use: Compressed Sensing GRASP-VIBE (GRASP = Golden-angle Radial Sparse Parallel MRI) is intended to be used in dynamic and/or non-contrast liver examinations to support patients who cannot reliably hold their breath for a conventional breath-hold measurement.