Contrast Enhanced Mammography
Digital mammography technology is continuing to progress. A new method is gaining more and more attention, especially for the diagnostic workup of recalled women: contrast-enhanced dual energy mammography (CEM). It combines contrast-enhanced (CE) imaging, which is familiar from computed tomography (CT), angiography, and magnetic resonance imaging (MRI), with the dual energy (DE) imaging used with CT and dual energy X-ray absorptiometry (DXA). The clinical value of CEM continues to be comprehensively studied.
What do our clinical experts have to say?
It’s important to understand how the method works and the experiences with CEM in the clinical routine so far. A webinar and a white paper aim to deepen these topics.
The clinical use of Wide-Angle Tomosynthesis and Titanium Contrast Enhanced Mammography
Titanium Contrast-Enhanced Mammography (TiCEM) White Paper
This white paper highlights the scientific backgrounds of opportunities for CEDEM (Contrast Enhanced Dual Energy Mammography) / TiCEM (Titanium Contrast-Enhanced Mammography) and discusses technological and clinical challenges, while presenting the current status of Siemens Healthineers’ research in this field (June 2018).
Related Publications on Contrast Enhanced Mammography
2. Sistermanns M, Kowall B, Hörnig M, Beiderwellen K, Uhlenbrock D. Motion Artifact Reduction in Contrast-Enhanced Dual-Energy Mammography - A Multireader Study about the Effect of Nonrigid Registration as Motion Correction on Image Quality. Rofo. 2021 Mar 18
Clinical utility of Contrast-Enhanced Dual Energy Mammography (CEDEM)
Luis Javier Pina Insausti; Pamplona, Spain
Abstract: Contrast-Enhanced Dual Energy Mammography (CEDEM) is a development of digital mammography. By using dual energy (conventional low-energy mammography plus high-energy mammography) after the administration of a bolus of intravenous iodinated contrast medium, a morpho-functional image of the breast is acquired. This technique joins the high spatial resolution of conventional digital mammography with functional information based on neoangiogenesis. The indications of this technique for clinical use include: problem–solving technique after inconclusive mammography, preoperative assessment of breast cancer, follow-up of scars after conservative treatment, and follow-up of intermediate-risk patients (borderline histological lesions, such as lobular carcinoma in situ, atypical ductal or lobular hyperplasia, and positive family history of breast cancer). In fact, the majority of indications are those of MRI, including the contraindications for MRI (pacemakers, claustrophobic patients, etc.). Nevertheless, CEDEM has some limitations: The sensitivity is lower for ductal carcinomas in situ, lesions out of the field of view of the detector are missed, and some benign lesions can enhance after contrast administration. CEDEM is contraindicated for patients allergic to iodine as well as for patients with renal insufficiency.
1. To become familiar with Contrast-Enhanced Dual Energy Mammography (CEDEM)
2. To learn the main indications for this technique
3. To learn the main limitations of CEDEM