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ADVIA Chemistry XPT System

An advanced automated clinical chemistry analyzer for high-volume laboratories

The ADVIA® Chemistry XPT System provides timely, reliable results with continuous operation to meet the chemistry workloads of the most demanding laboratories.

  • Delivers high throughput of up to 2400 tests per hour.
  • Manages comprehensive testing with a menu of more than 115 assays.
  • Improves workflow using automation and system technologies such as micro-volume and aliquot retention.
ADVIA Chemistry XPT System

ADVIA Chemistry XPT System

    Features & Benefits

    The ADVIA® Chemistry XPT System*** is engineered for continuous operation and timely, accurate results—supporting you to reach your full potential today and be prepared for tomorrow. With an advanced user interface that is easy to use and VeriSmart® Technology to support accuracy of testing, the ADVIA Chemistry XPT System predictably and consistently delivers timely, reliable results to meet expanding workloads. 

    Simplified, Continuous Operation
    • Simplify operation and training with the intuitive, icon-driven user interface.
    • Extend walkaway times with concentrated reagents that provide high test capacity onboard.
    • Quickly load most system fluids on the fly.
    • Automate calibration, QC, startup, and shutdown.
    Consistent, Predictable Turnaround Time and Accuracy

    Consistent, Predictable Turnaround Time and Accuracy

    • Offer a comprehensive chemistry menu of over 115 assays, including general and specialty chemistry, DAT, TDM, and specific proteins.
    • Push productivity with a throughput of up to 2400 tests per hour (1800 photometric, plus 600 ISE).
    • Control testing: STAT and specialty samples can always be front-loaded while an automation track is running.
    “Significantly, the system has demonstrated a turnaround time (TAT) at peak workload times almost as good as that of three chemistry systems. This proves that less equipment is needed to perform the same workload and achieve the same TAT.”
    Prof. Giorgia Bellomo
    Medical Director, Central Laboratory
    Hospital Ospedale Maggiore della Carità di Novara
    Prof. Giorgia BellomoMedical Director, Central LaboratoryHospital Ospedale Maggiore della Carità di Novara
    Prof. Giorgia Bellomo
    Medical Director, Central Laboratory
    Hospital Ospedale Maggiore della Carità di Novara
    Designed for Automation

    Designed for Automation

    "So far, the workload achievements resulted in 45 percent faster turnaround time for clinical chemistry testing."
    Dr. Hannes Wickert
    Specialist Doctor
    Labor Blackholm MVZ, Heilbronn, Germany
    Dr. Hannes WickertSpecialist DoctorLabor Blackholm MVZ, Heilbronn, Germany
    Dr. Hannes Wickert
    Specialist Doctor
    Labor Blackholm MVZ, Heilbronn, Germany
    Learn how micro-volume and aliquot retention innovations achieve more results with less sample, reagent, waste, and equipment.

    Do More with Less

    • Reduce blood-draw requirements with micro-volume technology that uses a single 30 μL sample for up to 15 tests.
    • Eliminate sample callback with automated, pre-programmable dilution, reflex, and rerun testing that uses an onboard aliquot.
    • Improve workflow and accuracy with VeriSmart® technologies that perform hardware and software checks at all stages of sample processing.

    Assays

    Diabetes
    Fructosamine
    Hemoglobin A1c (Enzymatic)

    Drugs of Abuse/Toxicology
    6-Acetylmorphine (6-AM)*
    Acetaminophen
    Amphetamines
    Barbiturates, Urine
    Barbiturates, Serum
    Benzodiazepines, Urine
    Benzodiazepines, Serum
    Buprenorphine*
    Cannabinoids (THC)
    Cocaine Metabolite
    Ecstasy
    EDDP††
    Ethyl Alcohol
    Ethyl Glucuronide (EtG)††,§§
    Fentanyl††

    Methadone
    Opiates
    Oxycodone*
    Phencyclidine
    Propoxyphene
    Salicylate
    Tramadol††

    General Chemistry

    Alanine Aminotransferase†
    Alanine Aminotransferase (P5P)†
    Albumin (BCG)†,‡
    Albumin (BCP)
    Alkaline Phosphatase (AMP)
    Ammonia
    Amylase
    Aspartate Aminotransferase†
    Aspartate Aminotransferase (P5P)†
    Bilirubin, Direct
    Bilirubin, Total
    Calcium (Arsenazo)†
    Calcium (CPC)†
    Carbon Dioxide (Enzymatic)
    Chloride
    Cholesterol†
    Cholinesterase
    Creatine Kinase
    Creatinine†
    Creatinine (Enzymatic)
    Gamma-Glutamyltransferase (GGT)
    Glucose (Hexokinase)†
    Glucose (Oxidase)†
    HDL Cholesterol
    Iron
    Lactate
    Lactate Dehydrogenase (L-P)
    Lactate Dehydrogenase (P-L)
    LDL Cholesterol
    Lipase
    Magnesium†
    Microalbumin
    Pancreatic Amylase
    Phosphorus†
    Potassium
    Sodium
    Total Iron Binding Capacity (TIBC)
    Total Protein†
    Total Protein, CSF/Urine
    Triglycerides†
    Urea Nitrogen (BUN)†
    Uric Acid†

    Specific Proteins
    α1-Acid Glycoprotein
    α1-Antitrypsin
    Antistreptolysin O
    Apolipoprotein A1
    Apolipoprotein B
    β-2 Microglobulin
    Complement C3
    Complement C4
    CRP
    CRP, High Sensitivity
    CRP, Wide Range
    Cystatin C
    Ferritin
    Haptoglobin
    Immunoglobulin A
    Immunoglobulin G
    Immunoglobulin M
    Lipoprotein(a)
    Prealbumin
    Rheumatoid Factor
    Soluble Transferrin Receptor (sTfR)§,††
    Transferrin

    Therapeutic Drug Monitoring
    Carbamazepine
    Digoxin
    Gentamicin
    Lamotrigine††
    Levetiracetam††
    Lithium
    Methotrexate**,††
    Phenobarbital
    Phenytoin
    Theophylline
    Tobramycin
    Valproic Acid
    Vancomycin

    Validity Testing
    Creatinine*,§§
    Nitrite*,§§
    Oxidant*,§§
    pH*,§§
    Specific Gravity*,§§

    Technical Specifications

    Product Specifications 

    System Description

    Fully random and continuous access, discrete processing clinical chemistry system with batch run capability

    Test Throughput

    Up to 2400 tests/hour: 1800 tests/hour photometric, 600 tests/hour ISE

    Assays Onboard

    59 assays, including 3 ISE (Na, K, Cl)

    Sample Handling

    Sample Tubes

    5 mL, 7 mL, and 10 mL tubes; 1 mL and 2 mL sample cups; user-defined containers

    Sample Tray

    84 sample positions; positive sample identification

    Validated Sample Types

    Serum, plasma, urine, whole blood, and CSF, assay-dependent

    Sample Integrity Control

    Qualitative check for hemolysis, lipemia, and icterus; clot detection, flagging, and management; short-sample detection, flagging, and management

    STAT Handling

    84 positions, not dedicated; STAT samples are processed with priority

    Auto-repeat Testing

    Automatic repeat testing from the retained prediluted sample or original sample

    Sample Dilution

    Automatic dilution up to 1:5625 from retained prediluted sample or original sample

    Auto-reflex Testing

    Automatic ability to perform additional tests based on results of first test or test combination

    Primary Sample Probe

    Liquid-level sensing, crash protection, clot/clog detection, liquid-surface verification

    Sample Carryover Prevention

    Automated wash; additional automated sample probe washes programmable for greater prevention

    Sample Throughput

    Up to 200 tubes per hour with ISE use; faster without ISE use

    Bar Codes  

    Sample Bar Codes

    Up to 20 digits; Interleaved 2 of 5, Code 39, Code 128, Codabar; A, B, and special characters (.-+/*$%)

    Micro-volume Technology  

    Automatic Sample Predilution

    Samples typically diluted 1:5 (30 μL sample + 120 μL saline generates up to 15 tests results); retained for auto-repeat, auto-reflex, or auto-dilution until results are available

    Predilution Tray

    120 dilution cuvettes

    Sample Volume per Test

    2–30 μL of prediluted sample, equating to 0.4–6.0 μL of original sample per test (varies by assay)

    Average Reagent Volume

    80–120 μL per test, assay-dependent

    Reaction Area  

    Reaction Cuvettes

    340 reusable optical-grade plastic cuvettes

    Reaction Bath

    Inert fluorocarbon oil circulation system, 37°C

    Photometer

    14 fixed wavelengths (340, 410, 451, 478, 505, 545, 571, 596, 658, 694, 751, 805, 845, and 884 nm)

    Light Source

    12V, 50W halogen lamp, cooled by forced water circulation

    Assay Result Calculations

    Endpoint (EPA), rate reaction (RRA), 2-point rate (2PA), constant rate analysis (CRA), and immunoassay analysis (IMA) methodologies; prozone checking; substrate depletion check; results available as completed

    Reaction Times

    3, 4, 5, and 10 minutes; extended reaction times 15 and 21 minutes

    Automatic Correction

    Sample blank, cuvette blank, measurement point change, sample volume change in re-assay

    Point Forwarding

    Can automatically extend linearity to measure samples over assay range

    Assay Technology

    Potentiometric, photometric, turbidimetric

    Reagent Handling

    Reagent Tray

    2 trays, (R1=60 and R2 =56 positions), refrigerated between 6°C and 13°C (43°F–55°F)

    Reagent Capacity Onboard

    56 photometric assays

    Test Capacity Onboard

    40,000 photometric tests average; over 100,000 photometric tests with the use of concentrated reagents

    Reagent Containers

    20, 40, 70 mL reagent wedges

    Reagent Integrity Control

    Bar-code reagent identification; automatic inventory tracking and flagging; calibration and control validity tracking and flagging; reagent onboard stability tracking and flagging; reagent expired/reagent low flagging

    Onboard Stability

    Up to 60 days, depending on assay

    Reagent Dilutions

    Capability to dilute concentrated reagents onboard

    Open-system Capability  

    Channels

    200 assay channels; includes 50 channels for user-defined applications

    Ion-selective Electrodes (ISE)

    ISE

    Indirect simultaneous measurement of Na+, K+, Cl-

    ISE Sample Volume

    22 μL original sample for all three tests

    Electrode Expected Use Life

    30,000 samples or 3 months, whichever occurs first

    Throughput Rate

    Up to 600 tests/hour; 200 tubes/hour

    Calibration/QC  

    Validated Calibration Interval

    Up to 60 days, tracked by software

    Auto-calibration

    User-defined time interval or with new reagent container

    Auto-QC

    User-defined test count interval or with auto-calibration

    View Calibration

    Graphical display of calibration curves

    QC Data

    Graphical display of QC; real-time/QC monitoring; Advanced QC package includes Levey-Jennings plots, Westgard rules, and RiliBÄK rules; 125,000 control results can be stored, archivable to removable media

    Calibration/Control Tray

    61 refrigerated positions for calibrators, controls, and diluents

    User Interface/Data Management  

    Monitor

    22-inch (55.9 cm) diagonal high-resolution LCD touchscreen with adjustable height

    Operating System

    Microsoft® Windows® 7

    System Documentation

    Operator manual, quickstart guide, and online help

    Data Storage

    500,000 active plus 500,000 historical test results; can archive to removable media

    Onboard Maintenance Logs

    Yes

    Host Interface

    TCP/IP bidirectional

    Host Query

    ASTM; system requests work order or batch of work orders from host

    Remote Access and Service

    Siemens Remote Service via 1000BASE-T Ethernet port

    Removable Media  

    Removable Media

    DVD, CD-RW, or USB

    General Specifications

    Power Requirements

    200–240V at 50/60 Hz, 3 kVA consumption

    Water Requirements

    CLSI® Clinical Laboratory Reagent Water or equivalent connected directly to a pressurized water source

    Maximum Water Consumption

    40 liters (10.6 gallons) per hour

    Drain Requirements

    Minimum of 40 liters (10.6 gallons) per hour

    Dimensions

    With monitor: 149 (h) x 177 (w) x 99 (d) cm; 59 (h) x 70 (w) x 39 (d) inches
    Without monitor: 134 (h) x 177 (w) x 99 (d) cm; 53 (h) x 70 (w) x 39 (d) inches

    Weight

    725 kg (1598 lb)

    Compliance

    Complies with international environmental, health, and safety standards, including CE and RoHS

    Noise Emission

    Less than 62 dB

    Processing Heat Output

    5374 BTU/hour

    Ambient Temperature

    18°–30°C (64°-86°F)

    Ambient Humidity

    20–80% noncondensing

    * Alliance Application manufactured and distributed by Siemens Healthcare Diagnostics.

    † Also available in concentrated version.

    ‡ ADVIA Chemistry XPT System supports concentrated version only.

    § Not available for sale in the U.S.

    ** Not currently available on the ADVIA Chemistry XPT System.

    †† Alliance Application manufactured by third party, distributed by Siemens Healthcare Diagnostics.

    ‡‡ In development, future availability cannot be guaranteed.

    §§ Restricted in the U.S. to law enforcement-related use (forensic use only).


    *** Due to local regulations, not all products are available in all countries.


    The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.


    Product availability may vary from country to country and is subject to varying regulatory requirements. Please contact your local representative for availability.


    The outcomes achieved by the Siemens Healthineers customers described herein were achieved in each customer’s unique setting. Since there is no “typical” hospital and many variables exist (e.g., hospital size, case mix, level of IT adoption) there can be no guarantee that others will achieve the same results.