MyoglobinAn early biomarker to aid in the diagnosis of myocardial infarction
The Acute Care™ myoglobin assay is an in vitro diagnostic test for the measurement of myoglobin in heparinized whole blood /plasma. Myoglobin measurements can be used as an aid in diagnosing myocardial infarction.
- One sample, one run, one instrument; increases efficiency in triaging chest pain patients
- Laboratory quality performance and quantitative results from whole blood in the near-patient care setting
- Can be used as an aid in diagnosing myocardial infarction
Features & Benefits
- One sample, one run, one instrument; increases efficiency in triaging chest pain patients
- Rapid turnaround time - in as little as 14 minutes (with onboard centrifugation)
- Laboratory quality performance and quantitative results from whole blood in the near-patient care setting
- Single and ready to use TestPak™ Cartridges
o No reconstitution
o No warming to room temperature
o Reduction in reagent waste
o Reduction in contamination - Heparinized whole blood samples
- Electronic QC (System Check) satisfies daily routine QC requirements permitting liquid QC flexibility
Clinical Use
Following myocadial necrosis associated with myocardial infarction (MI), myoglobin is one of the first markers to rise above normal levels, increasing measurably above baseline within 2-4 hours post-infarct, peaking at 9-12 hours, and returning to baseline within 24-36 hours.1,2 In the absence of skeletal muscle trauma or other factors associated with a non-cardiac related increase in circulating myoglobin, myoglobin levels have been used as an early marker for MI.3,4 A number of reports suggest the measurement of myoglobin as a diagnostic aid in “ruling-out” myocardial infarction with negative predictive values of up to 100% reported at certain time periods after onset of symptoms.
Technical Specifications
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Mair J, et al. Rapid diagnosis of myocardial infarction by immunoturbidimetric myoglobin measurement (letter). Lancet, 1991;337:1343.
Chapelle, JP. Myoglobin. Clin Chem. News, 1991;17:22.
Silva DP, et al. Development and application of antibodies to human cardiac myoglobin in rapid fluorescence Immunoassay. Clin. Chem., 1991;37:1356.
Hamfelt A, et al. Use of biochemical tests for myocardial infarction in the county of Vasternorrland, a clinical chemistry Routine for the diagnosis of myocardial infarction. Scand. J. Clin. Lab. Invest. Suppl.,1990;200:20.
The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens organization for further details.