Treating Chronic Total Occlusions (CTOs) is one of the most challenging procedures in interventional cardiology. Incomplete crossing of the lesion is a high risk. syngo CTO Guidance enables better planning with automatic segmentation of coronary CTAs. Further, it provides guidance during the procedure with color-coded COROwave to avoid foreshortening. This enables more physicians to treat complex CTO cases and helps to expand the hospital’s procedure mix.