ADVIA Centaur XPT Immunoassay System
An advanced automated immunoassay analyzer designed for continuous operation
The ADVIA Centaur® XPT Immunoassay System is engineered for simplified, continuous operation and timely, trusted results.
- Responds to peak testing needs with a throughput of up to 240 tests per hour and no-pause loading of reagents, consumables, and samples.
- Supports comprehensive diagnoses with a menu of over 70 assays.
- Continually expands testing with advanced acridinium ester technology—evolving chemiluminescence that provides the flexibility to meet changing clinical needs.
ADVIA Centaur XPT Immunoassay System
Simplify operations
Expand testing
Uninterrupted Processing
Automation-ready
Features & Benefits
"The ADVIA Centaur XPT System exceeded our expectations. Furthermore, we could reduce the monthly maintenance by 12 hours per year and operator maintenance time by 60%." Dr. Roberto Rosso
ASST Ovest Milano
Laboratory Supervisor
Ospedale di Magenta
Cutting-edge AE Immunoassay Technology
- Meet evolving clinical needs with advanced acridinium ester technology, which provides flexibility and sensitivity for new and innovative assays.
- Manage comprehensive disease-state testing with a menu of more than 70 assays.
- Simplify inventory management and reduce cost with the same highly stable, ready-to-use reagents used on all ADVIA Centaur analyzers.
Simplified, Continuous Operation
- Load and unload all samples, reagents, and supplies without pausing the system.
- Simplify operation and training with an intuitive, icon-driven user interface.
- Reduce hands-on time with low daily maintenance and no monthly cleaning or daily startup procedures.
- Implement new assays immediately with one easy scan of a test definition bar code.
Consistent, Predictable Turnaround Time and Accuracy
- Deliver up to 240 tests per hour for fast turnaround, even during peak workload times.
- React fast with a STAT port that allows priority sampling at any time.
- Improve result integrity with disposable probe tips that eliminate sample-to-sample carryover.
- Conduct automatic repeat and confirmatory testing of reactive hepatitis B surface antigen samples using Siemens Healthineers unique SMART algorithm software.
Seamless Connectivity
See how Labor Blackholm MVZ increased testing volume by 34% with 30% fewer analyzers
- Adapt and grow as workloads demand by connecting directly to Aptio® Automation and VersaCell® X3 Solution.
- Streamline operations with diagnostics IT, including CentraLink® Data Management System, Atellica® Process Manager and Siemens Remote Service (SRS).
- Sample directly from the track using point-in-space technology.
- Drive rapid turnaround time with a dedicated STAT port that can also front-load priority samples when connected to automation.
Assays
Anemia
Active B12
EPO†
Ferritin
Folate
RBC Folate
Vitamin B12
Autoimmune
Anti-CCP
Bone Metabolism
Intact PTH
Vitamin D Total
Cardiac
BNP
CKMB
High-Sensitivity Troponin I (TNIH)
Myoglobin
NT-proBNP†
TnI-Ultra™
Diabetes
C-Peptide
Insulin
Hepatitis
Anti-HBe†
Anti-HBs 2
HAV IgM
HAV Total
HBc IgM
HBc Total
HBeAg
HBsAgII
HBsAgII Quant†
HBsAg Confirmatory
HCV**
HIV
HIV 1/O/2 Enhanced (EHIV)§
HIV Combo§
Immunosuppressant Drugs
Cyclosporine
Everolimus*
Sirolimus*
Inflammation
IgE, Total
IL-6†
LBP†
Liver Fibrosis
Enhanced Liver Fibrosis (ELF™) Test†
HA (ELF™ Marker)†
PIIINP (ELF™ Marker)†
TIMP (ELF™ Marker)†
Metabolic
Cortisol
Homocysteine
Oncology
AFP
BR 27.29
CA 125II‡
CA 15-3
CA 19-9
Calcitonin
CEA
Complexed PSA
Free PSA†
PSA
Serum HER-2/neu
Reproductive Endocrinology
AFP
Anti-Müllerian Hormone*
DHEAS
Enhanced Estradiol
Free βhCG‡‡
FSH
hCG
LH
PAPP-A‡‡
PlGF*
Progesterone
Prolactin
sFLT-1*
SHBG
Testosterone II
Sepsis
Procalcitonin†
Special ID
Syphilis
EBV-EBNA IgG*
EBV-VCA IgG*
EBV-VCA IgM*
Zika IgM††
Therapeutic Drug Monitoring (TDM)
Carbamazepine
Digitoxin
Digoxin
Gentamicin
Phenobarbital
Phenytoin
Theophylline
Valproic Acid
Vancomycin
Thyroid
Anti-Tg
Anti-TPO
Free T3
Free T4
T Uptake
Total T3
Total T4
TSH3-Ultra
TSH
ToRCH
CMV IgG
CMV IgM*
Herpes-1 IgG
Herpes-2 IgG
Rubella IgG
Rubella IgM
Toxoplasma IgG
Toxoplasma IgM
Technical Specifications
| Product Specifications | |
| System Description | Random-access immunoassay system |
| Test Throughput | Up to 240 tests per hour |
| Time to First Result | 18 minutes; results every 15 seconds thereafter, assay dependent |
| Assays Onboard | 30 assays |
| Disease-State Assay Groups§§ | Allergy, Anemia/Iron Metabolism, Bone Metabolism, Cardiac, Diabetes, Hepatitis, HIV, Immunosuppressant Drugs, Liver Fibrosis†, Metabolic, Oncology, Reproductive Endocrinology, Sepsis†, Special ID, Therapeutic Drug Monitoring (TDM), Thyroid, ToRCH |
| Continuous Operation | Loading/unloading of samples and consumables at any time without interrupting system operation. Includes sample racks, STATs, reagent packs, ancillary reagent packs, reaction cuvettes, sample pipette tips, calibrators, controls, wash fluids, water, and waste. |
| Sample Handling | |
| Sample Tubes | 3 mL, 5 mL, 7 mL, and 10 mL tubes; 1 mL and 2 mL sample cups; microcontainer tubes |
| Sample Input | Universal 5-position rack holds multiple tube types; 180 samples fully loaded; no-pause loading and unloading |
| Validated Sample Types | Serum, plasma, urine (assay-dependent) |
| Sample Volume per Test | 10–200 μL, assay-dependent |
| Sample Integrity Control | Pressure transducer technology with clot detection, flagging, and management; short-sample detection |
| STAT Handling | Dedicated STAT port accepts samples any time; STAT samples are processed with priority |
| Auto-repeat | User-definable |
| Sample Dilution | Automatic dilution varies by assay, up to 1:2500 |
| Auto-reflex Testing | Automatic ability to perform additional tests based on results of first test |
| Sample Pipette Tips | 840 disposable sample tip capacity |
| Sample Carryover Prevention | Disposable pipette tips ensure zero sample carryover |
| Bar Codes | |
| Sample Bar Codes | Up to 20 digits; Interleaved 2 of 5; Code 39, Code 128, Codabar; A, B, and special characters (.-+/*$%) |
| Reaction Area | |
| Reaction Cuvettes | Capacity of 1000 optical-grade plastic cuvettes |
| Reaction Bath | Air bath, 37°C |
| Assay Result Calculations | SMART algorithm software repeats and confirms reactive testing; results available as completed |
| Assay Technology | Chemiluminescence using Advanced Acridinium Ester |
| Reagent Handling | |
| Reagent Tray | 30-position reagent tray refrigerated between 4 and 10°C (39–50°F) |
| Reagent Capacity Onboard | 30 assays |
| Reagent Containers | ADVIA Centaur® ReadyPack® (various pack sizes available) |
| Reagent Integrity Control | Bar-code reagent identification, automatic inventory tracking and flagging, calibration valid tracking and flagging, reagent onboard stability tracking and flagging, reagent expired/reagent low flagging |
| Onboard Stability | 28 days (average) |
| Reagent Mixing | ADVIA Centaur ReadyPacks automatically rocked onboard |
| Ancillary Reagents | 25-position ancillary reagent tray cooled 4–8°C (39–46°F) |
| Calibration/QC | |
| Auto-calibration/Auto-QC | Available automatic QC ordering by test, control, date, and time |
| QC Data | Advanced QC package includes Levey-Jennings plots and Westgard rules |
| User Interface/Data Management | |
| Monitor | 22-inch diagonal high-resolution LCD touchscreen with adjustable height |
| Operating System | Microsoft Windows 7 |
| System Documentation | Operator manual, quickstart guide, and context-sensitive online help |
| Data Storage | 1,000,000 test/QC results; 500,000 can be historical; can archive to removable media |
| Onboard Maintenance Logs | Yes |
| Host Interface | RS232C bidirectional and host query; Ethernet connection available |
| Host Query | Yes |
| Remote Access & Service | 1000Base-T Ethernet port for remote access and modem for Siemens Remote Service |
| Removable Media | |
| Removable Media | CD, DVD, or USB |
| General Specifications | |
| Power Requirements | 200-240 V at 50/60 Hz; 1.2 kW maximum |
| Maximum Water Consumption | 2.5 liters (0.6 gallons) per hour |
| Drain Requirements | Minimum of 2.5 liters (0.6 gallons) per hour |
| Dimensions | With monitor: 167 (h) x 196 (w) x 104 (d) cm; 66 (h) x 77 (w) x 41 (d) in. Without monitor: 133 (h) x 196 (w) x 104 (d) cm; 52 (h) x 77 (w) x 41 (d) in. |
| Weight | 585 kg (1289 lb) |
| Compliance | Complies with international environmental, health, and safety standards |
| Noise Emission | 65 dB maximum |
| Processing Heat Output | 5100 BTU/hour |
| Ambient Temperature | 18–30°C (64–86°F) |
| Ambient Humidity | 20–80% noncondensing |
| Floor Load-Bearing Requirement | 412 kg/m2 (84 lb/ft2) |
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Related Products, Services & Resources
* Under development. Not available for sale.
† Not available for sale in the U.S.
‡CA 125II is a trademark of Fujirebio Diagnostics, Inc.
§ Assay developed, manufactured, and sold by Siemens Healthcare Diagnostics Inc. for Ortho Clinical Diagnostics, Inc. and Grifols Diagnostic Solutions Inc.
** For outside of the U.S. only, assay developed, manufactured, and sold by Siemens Healthcare Diagnostics Inc. for Ortho Clinical Diagnostics, Inc. and Grifols Diagnostic Solutions Inc.
†† The ADVIA Centaur Zika Test has not been FDA cleared or approved. This test has been authorized by FDA under an EUA for use by authorized laboratories. This test has been authorized only for the diagnosis for Zika virus infection and not for any other viruses or pathogens. This test is only authorized for the duration of the declaration that circumstances exist justifying the authorization of the emergency use of in vitro diagnostic tests for detection of Zika virus and/or diagnosis of Zika virus infection under section 564(b)(1) of the Act, 21 U.S.C. § 360bbb-3(b)(1), unless the authorization is terminated or revoked sooner.
‡‡ For Research Use Only in the U.S. Not for use in clinical or diagnostic procedures in the U.S.
§§ Due to local regulations, not all products are available in all countries.
The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.
The outcomes achieved by the Siemens Healthineers customers described herein were achieved in each customer’s unique setting. Since there is no “typical” hospital and many variables exist (e.g., hospital size, case mix, level of IT adoption) there can be no guarantee that others will achieve the same results.