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ADVIA Centaur XPT Immunoassay SystemAn advanced automated immunoassay analyzer designed for continuous operation

ADVIA Centaur XPT Immunoassay System
ADVIA Centaur XPT Immunoassay System

    The ADVIA Centaur® XPT Immunoassay System is engineered for simplified, continuous operation and timely, trusted results.

    • Responds to peak testing needs with a throughput of up to 240 tests per hour and no-pause loading of reagents, consumables, and samples.
    • Supports comprehensive diagnoses with a menu of over 70 assays.
    • Continually expands testing with advanced acridinium ester technology—evolving chemiluminescence that provides the flexibility to meet changing clinical needs.
    ADVIA Centaur XPT Immunoassay System
    ADVIA Centaur XPT Immunoassay System

      Features & Benefits

      "The ADVIA Centaur XPT System exceeded our expectations. Furthermore, we could reduce the monthly maintenance by 12 hours per year and operator maintenance time by 60%."
      Dr. Roberto Rosso
      ASST Ovest Milano
      Laboratory Supervisor
      Ospedale di Magenta
      Dr. Roberto RossoASST Ovest MilanoLaboratory SupervisorOspedale di Magenta
      Dr. Roberto Rosso
      ASST Ovest Milano
      Laboratory Supervisor
      Ospedale di Magenta
      See how advanced acridinium ester chemiluminescence works

        Cutting-edge AE Immunoassay Technology

        • Meet evolving clinical needs with advanced acridinium ester technology, which provides flexibility and sensitivity for new and innovative assays.
        • Manage comprehensive disease-state testing with a menu of more than 70 assays.
        • Simplify inventory management and reduce cost with the same highly stable, ready-to-use reagents used on all ADVIA Centaur analyzers.
        Learn how the ADVIA Centaur XPT System reduced analyzer maintenance by 67% at ASST Ovest Milano, Ospedale di Magenta

          Simplified, Continuous Operation

          Learn how the ADVIA Centaur XPT System reduced analyzer maintenance by 67% at ASST Ovest Milano, Ospedale di Magenta

          • Load and unload all samples, reagents, and supplies without pausing the system.
          • Simplify operation and training with an intuitive, icon-driven user interface.
          • Reduce hands-on time with low daily maintenance and no monthly cleaning or daily startup procedures.
          • Implement new assays immediately with one easy scan of a test definition bar code.
          Learn how Hospital Clinic de Barcelona improved immunoassay turnaround times

            Consistent, Predictable Turnaround Time and Accuracy

            Learn how Laboratory Dr. Quade and Colleagues GmbH increased overall laboratory productivity with the ADVIA Centaur XPT Immunoassay System

            • Deliver up to 240 tests per hour for fast turnaround, even during peak workload times.
            • React fast with a STAT port that allows priority sampling at any time.
            • Improve result integrity with disposable probe tips that eliminate sample-to-sample carryover.
            • Conduct automatic repeat and confirmatory testing of reactive hepatitis B surface antigen samples using Siemens Healthineers unique SMART algorithm software.
            See how Labor Blackholm MVZ increased testing volume by 34% with 30% fewer analyzers

              Seamless Connectivity

              See how Labor Blackholm MVZ increased testing volume by 34% with 30% fewer analyzers

              Assays

              Anemia
              Active B12
              EPO
              Ferritin
              Folate
              RBC Folate
              Vitamin B12 

              Autoimmune
              Anti-CCP 

              Bone Metabolism
              Intact PTH
              Vitamin D Total 

              Cardiac
              BNP
              CKMB
              High-Sensitivity Troponin I (TNIH)
              Myoglobin
              NT-proBNP† 

              Diabetes
              C-Peptide
              Insulin 

              Hepatitis
              Anti-HBe†
              Anti-HBs 2
              HAV IgM
              HAV Total
              HBc IgM
              HBc Total
              HBc Total2†
              HBeAg
              HBsAg Confirmatory
              HBsAgII
              HBsAgII Quant
              HCV§

              HIV
              HIV 1/O/2 Enhanced (EHIV)§
              HIV Combo (CHIV)§

              Immunosuppressant Drugs
              Cyclosporine
              Everolimus*
              Sirolimus*

              Inflammation
              IgE, Total
              IL-6†
              LBP†

              Liver Fibrosis
              Enhanced Liver Fibrosis (ELF™) Test†
              HA (ELF™ Marker)†
              PIIINP (ELF™ Marker)†
              TIMP (ELF™ Marker)†

              Metabolic
              Cortisol
              Homocysteine 

              Neurology
              TTAU (Total-Tau)*
              AB42 (β-Amyloid 1-42)*

              Oncology
              AFP
              BR 27.29
              CA 125II‡
              CA 15-3‡
              CA 19-9
              Calcitonin
              CEA
              Complexed PSA
              CYFRA 21-1*‡
              Free PSA†
              NSE*
              PSA
              SCC*‡
              Serum HER-2/neu 

              Reproductive Endocrinology
              AFP
              Androstenedione
              Anti-Müllerian Hormone*
              DHEAS
              Enhanced Estradiol
              Free βhCG
              FSH
              hCG
              LH
              PAPP-A
              PlGF*
              Progesterone
              Prolactin
              sFLT-1*
              SHBG
              Testosterone II 

              Sepsis
              Procalcitonin (PCT)† 

              Special ID
              EBV-EBNA IgG*
              EBV-VCA IgG*
              EBV-VCA IgM*
              Syphilis
              Zika IgM** 

              Therapeutic Drug Monitoring (TDM)
              Carbamazepine
              Digitoxin
              Digoxin
              Gentamicin
              Phenobarbital
              Phenytoin
              Theophylline
              Valproic Acid
              Vancomycin 

              Thyroid
              Anti-TgII
              Anti-TPO
              Free T3
              Free T4
              T Uptake
              Total T3
              Total T4
              TSH3-Ultra
              TSH 

              ToRCH
              CMV IgG
              CMV IgM*
              Herpes-1 IgG
              Herpes-2 IgG
              Rubella IgGII
              Rubella IgM
              Toxoplasma IgG
              Toxoplasma IgM

              Technical Specifications

              Product Specifications

               

              System Description

              Random-access immunoassay system

              Test Throughput

              Up to 240 tests per hour

              Time to First Result

              18 minutes; results every 15 seconds thereafter, assay dependent

              Assays Onboard

              30 assays

              Disease-State Assay Groups§§

              Allergy, Anemia/Iron Metabolism, Bone Metabolism, Cardiac, Diabetes, Hepatitis, HIV, Immunosuppressant Drugs, Liver Fibrosis†, Metabolic, Oncology, Reproductive Endocrinology, Sepsis†, Special ID, Therapeutic Drug Monitoring (TDM), Thyroid, ToRCH

              Continuous Operation

              Loading/unloading of samples and consumables at any time without interrupting system operation. Includes sample racks, STATs, reagent packs, ancillary reagent packs, reaction cuvettes, sample pipette tips, calibrators, controls, wash fluids, water, and waste.

              Sample Handling

               

              Sample Tubes

              3 mL, 5 mL, 7 mL, and 10 mL tubes; 1 mL and 2 mL sample cups; microcontainer tubes

              Sample Input

              Universal 5-position rack holds multiple tube types; 180 samples fully loaded; no-pause loading and unloading

              Validated Sample Types

              Serum, plasma, urine (assay-dependent)

              Sample Volume per Test

              10–200 μL, assay-dependent

              Sample Integrity Control

              Pressure transducer technology with clot detection, flagging, and management; short-sample detection

              STAT Handling

              Dedicated STAT port accepts samples any time; STAT samples are processed with priority

              Auto-repeat

              User-definable

              Sample Dilution

              Automatic dilution varies by assay, up to 1:2500

              Auto-reflex Testing

              Automatic ability to perform additional tests based on results of first test

              Sample Pipette Tips

              840 disposable sample tip capacity

              Sample Carryover Prevention

              Disposable pipette tips ensure zero sample carryover

              Bar Codes

               

              Sample Bar Codes

              Up to 20 digits; Interleaved 2 of 5; Code 39, Code 128, Codabar; A, B, and special characters (.-+/*$%)

              Reaction Area

               

              Reaction Cuvettes

              Capacity of 1000 optical-grade plastic cuvettes

              Reaction Bath

              Air bath, 37°C

              Assay Result Calculations

              SMART algorithm software repeats and confirms reactive testing; results available as completed

              Assay Technology

              Chemiluminescence using Advanced Acridinium Ester

              Reagent Handling

               

              Reagent Tray

              30-position reagent tray refrigerated between 4 and 10°C (39–50°F)

              Reagent Capacity Onboard

              30 assays

              Reagent Containers

              ADVIA Centaur® ReadyPack® (various pack sizes available)

              Reagent Integrity Control

              Bar-code reagent identification, automatic inventory tracking and flagging, calibration valid tracking and flagging, reagent onboard stability tracking and flagging, reagent expired/reagent low flagging

              Onboard Stability

              28 days (average)

              Reagent Mixing

              ADVIA Centaur ReadyPacks automatically rocked onboard

              Ancillary Reagents

              25-position ancillary reagent tray cooled 4–8°C (39–46°F)

              Calibration/QC

               

              Auto-calibration/Auto-QC

              Available automatic QC ordering by test, control, date, and time

              QC Data

              Advanced QC package includes Levey-Jennings plots and Westgard rules

              User Interface/Data Management

               

              Monitor

              22-inch diagonal high-resolution LCD touchscreen with adjustable height

              Operating System

              Microsoft Windows 7

              System Documentation

              Operator manual, quickstart guide, and context-sensitive online help

              Data Storage

              1,000,000 test/QC results; 500,000 can be historical; can archive to removable media

              Onboard Maintenance Logs

              Yes

              Host Interface

              RS232C bidirectional and host query; Ethernet connection available

              Host Query

              Yes

              Remote Access & Service

              1000Base-T Ethernet port for remote access and modem for Siemens Remote Service

              Removable Media

               

              Removable Media

              CD, DVD, or USB

              General Specifications

               

              Power Requirements

              200-240 V at 50/60 Hz; 1.2 kW maximum

              Maximum Water Consumption

              2.5 liters (0.6 gallons) per hour

              Drain Requirements

              Minimum of 2.5 liters (0.6 gallons) per hour

              Dimensions

              With monitor: 167 (h) x 196 (w) x 104 (d) cm; 66 (h) x 77 (w) x 41 (d) in.
              Without monitor: 133 (h) x 196 (w) x 104 (d) cm; 52 (h) x 77 (w) x 41 (d) in.

              Weight

              585 kg (1289 lb)

              Compliance

              Complies with international environmental, health, and safety standards

              Noise Emission

              65 dB maximum

              Processing Heat Output

              5100 BTU/hour

              Ambient Temperature

              18–30°C (64–86°F)

              Ambient Humidity

              20–80% noncondensing

              Floor Load-Bearing Requirement

              412 kg/m2 (84 lb/ft2)

              * Under development. Not available for sale.

              † Not available for sale in the U.S.

              ‡ CA 125II is a trademark of Fujirebio Diagnostics, Inc.

              § Assay developed, manufactured, and sold by Siemens Healthcare Diagnostics Inc. for Ortho Clinical Diagnostics, Inc. and Grifols Diagnostic Solutions Inc.

              ** Available in the U.S. only. Limited distribution.

              The outcomes achieved by the Siemens Healthineers customers described herein were achieved in each customer’s unique setting. Since there is no “typical” hospital and many variables exist (e.g., hospital size, case mix, level of IT adoption) there can be no guarantee that others will achieve the same results.

              The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.