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ADVIA Centaur XPT Immunoassay SystemAn advanced automated immunoassay analyzer designed for continuous operation

ADVIA Centaur XPT Immunoassay System
ADVIA Centaur XPT Immunoassay System

    The ADVIA Centaur® XPT Immunoassay System is engineered for simplified, continuous operation and timely, trusted results.

    • Responds to peak testing needs with a throughput of up to 240 tests per hour and no-pause loading of reagents, consumables, and samples.
    • Supports comprehensive diagnoses with a menu of over 70 assays.
    • Continually expands testing with advanced acridinium ester technology—evolving chemiluminescence that provides the flexibility to meet changing clinical needs.
    ADVIA Centaur XPT Immunoassay System
    ADVIA Centaur XPT Immunoassay System

      Features & Benefits

      "The ADVIA Centaur XPT System exceeded our expectations. Furthermore, we could reduce the monthly maintenance by 12 hours per year and operator maintenance time by 60%."
      Dr. Roberto Rosso
      ASST Ovest Milano
      Laboratory Supervisor
      Ospedale di Magenta
      Dr. Roberto RossoASST Ovest MilanoLaboratory SupervisorOspedale di Magenta
      Dr. Roberto Rosso
      ASST Ovest Milano
      Laboratory Supervisor
      Ospedale di Magenta
      See how advanced acridinium ester chemiluminescence works

      Cutting-edge AE Immunoassay Technology

      • Meet evolving clinical needs with advanced acridinium ester technology, which provides flexibility and sensitivity for new and innovative assays.
      • Manage comprehensive disease-state testing with a menu of more than 70 assays.
      • Simplify inventory management and reduce cost with the same highly stable, ready-to-use reagents used on all ADVIA Centaur analyzers.
      Learn how the ADVIA Centaur XPT System reduced analyzer maintenance by 67% at ASST Ovest Milano, Ospedale di Magenta

      Simplified, Continuous Operation

      Learn how the ADVIA Centaur XPT System reduced analyzer maintenance by 67% at ASST Ovest Milano, Ospedale di Magenta

      • Load and unload all samples, reagents, and supplies without pausing the system.
      • Simplify operation and training with an intuitive, icon-driven user interface.
      • Reduce hands-on time with low daily maintenance and no monthly cleaning or daily startup procedures.
      • Implement new assays immediately with one easy scan of a test definition bar code.
      Learn how Hospital Clinic de Barcelona improved immunoassay turnaround times

      Consistent, Predictable Turnaround Time and Accuracy

      Learn how Laboratory Dr. Quade and Colleagues GmbH increased overall laboratory productivity with the ADVIA Centaur XPT Immunoassay System

      • Deliver up to 240 tests per hour for fast turnaround, even during peak workload times.
      • React fast with a STAT port that allows priority sampling at any time.
      • Improve result integrity with disposable probe tips that eliminate sample-to-sample carryover.
      • Conduct automatic repeat and confirmatory testing of reactive hepatitis B surface antigen samples using Siemens Healthineers unique SMART algorithm software.
      See how Labor Blackholm MVZ increased testing volume by 34% with 30% fewer analyzers

      Seamless Connectivity

      See how Labor Blackholm MVZ increased testing volume by 34% with 30% fewer analyzers

      Assays

      Anemia
      Active B12
      EPO
      Ferritin
      Folate
      RBC Folate
      Vitamin B12 

      Autoimmune
      Anti-CCP 

      Bone Metabolism
      Intact PTH
      Vitamin D Total 

      Cardiac
      BNP
      CKMB
      High-Sensitivity Troponin I (TNIH)
      Myoglobin
      NT-proBNP† 

      Diabetes
      C-Peptide
      Insulin 

      Hepatitis
      Anti-HBe†
      Anti-HBs 2
      HAV IgM
      HAV Total
      HBc IgM
      HBc Total
      HBc Total2†
      HBeAg
      HBsAg Confirmatory
      HBsAgII
      HBsAgII Quant
      HCV§

      HIV
      HIV 1/O/2 Enhanced (EHIV)§
      HIV Combo (CHIV)§

      Immunosuppressant Drugs
      Cyclosporine
      Everolimus*
      Sirolimus*

      Inflammation
      IgE, Total
      IL-6†
      LBP†

      Liver Fibrosis
      Enhanced Liver Fibrosis (ELF™) Test†
      HA (ELF™ Marker)†
      PIIINP (ELF™ Marker)†
      TIMP (ELF™ Marker)†

      Metabolic
      Cortisol
      Homocysteine 

      Neurology
      TTAU (Total-Tau)*
      AB42 (β-Amyloid 1-42)*

      Oncology
      AFP
      BR 27.29
      CA 125II‡
      CA 15-3‡
      CA 19-9
      Calcitonin
      CEA
      Complexed PSA
      CYFRA 21-1*‡
      Free PSA†
      NSE*
      PSA
      SCC*‡
      Serum HER-2/neu 

      Reproductive Endocrinology
      AFP
      Androstenedione
      Anti-Müllerian Hormone*
      DHEAS
      Enhanced Estradiol
      Free βhCG
      FSH
      hCG
      LH
      PAPP-A
      PlGF*
      Progesterone
      Prolactin
      sFLT-1*
      SHBG
      Testosterone II 

      Sepsis
      Procalcitonin (PCT)† 

      Special ID
      EBV-EBNA IgG*
      EBV-VCA IgG*
      EBV-VCA IgM*
      Syphilis
      Zika IgM** 

      Therapeutic Drug Monitoring (TDM)
      Carbamazepine
      Digitoxin
      Digoxin
      Gentamicin
      Phenobarbital
      Phenytoin
      Theophylline
      Valproic Acid
      Vancomycin 

      Thyroid
      Anti-TgII
      Anti-TPO
      Free T3
      Free T4
      T Uptake
      Total T3
      Total T4
      TSH3-Ultra
      TSH 

      ToRCH
      CMV IgG
      CMV IgM*
      Herpes-1 IgG
      Herpes-2 IgG
      Rubella IgGII
      Rubella IgM
      Toxoplasma IgG
      Toxoplasma IgM

      Technical Specifications

      Product Specifications

       

      System Description

      Random-access immunoassay system

      Test Throughput

      Up to 240 tests per hour

      Time to First Result

      18 minutes; results every 15 seconds thereafter, assay dependent

      Assays Onboard

      30 assays

      Disease-State Assay Groups§§

      Allergy, Anemia/Iron Metabolism, Bone Metabolism, Cardiac, Diabetes, Hepatitis, HIV, Immunosuppressant Drugs, Liver Fibrosis†, Metabolic, Oncology, Reproductive Endocrinology, Sepsis†, Special ID, Therapeutic Drug Monitoring (TDM), Thyroid, ToRCH

      Continuous Operation

      Loading/unloading of samples and consumables at any time without interrupting system operation. Includes sample racks, STATs, reagent packs, ancillary reagent packs, reaction cuvettes, sample pipette tips, calibrators, controls, wash fluids, water, and waste.

      Sample Handling

       

      Sample Tubes

      3 mL, 5 mL, 7 mL, and 10 mL tubes; 1 mL and 2 mL sample cups; microcontainer tubes

      Sample Input

      Universal 5-position rack holds multiple tube types; 180 samples fully loaded; no-pause loading and unloading

      Validated Sample Types

      Serum, plasma, urine (assay-dependent)

      Sample Volume per Test

      10–200 μL, assay-dependent

      Sample Integrity Control

      Pressure transducer technology with clot detection, flagging, and management; short-sample detection

      STAT Handling

      Dedicated STAT port accepts samples any time; STAT samples are processed with priority

      Auto-repeat

      User-definable

      Sample Dilution

      Automatic dilution varies by assay, up to 1:2500

      Auto-reflex Testing

      Automatic ability to perform additional tests based on results of first test

      Sample Pipette Tips

      840 disposable sample tip capacity

      Sample Carryover Prevention

      Disposable pipette tips ensure zero sample carryover

      Bar Codes

       

      Sample Bar Codes

      Up to 20 digits; Interleaved 2 of 5; Code 39, Code 128, Codabar; A, B, and special characters (.-+/*$%)

      Reaction Area

       

      Reaction Cuvettes

      Capacity of 1000 optical-grade plastic cuvettes

      Reaction Bath

      Air bath, 37°C

      Assay Result Calculations

      SMART algorithm software repeats and confirms reactive testing; results available as completed

      Assay Technology

      Chemiluminescence using Advanced Acridinium Ester

      Reagent Handling

       

      Reagent Tray

      30-position reagent tray refrigerated between 4 and 10°C (39–50°F)

      Reagent Capacity Onboard

      30 assays

      Reagent Containers

      ADVIA Centaur® ReadyPack® (various pack sizes available)

      Reagent Integrity Control

      Bar-code reagent identification, automatic inventory tracking and flagging, calibration valid tracking and flagging, reagent onboard stability tracking and flagging, reagent expired/reagent low flagging

      Onboard Stability

      28 days (average)

      Reagent Mixing

      ADVIA Centaur ReadyPacks automatically rocked onboard

      Ancillary Reagents

      25-position ancillary reagent tray cooled 4–8°C (39–46°F)

      Calibration/QC

       

      Auto-calibration/Auto-QC

      Available automatic QC ordering by test, control, date, and time

      QC Data

      Advanced QC package includes Levey-Jennings plots and Westgard rules

      User Interface/Data Management

       

      Monitor

      22-inch diagonal high-resolution LCD touchscreen with adjustable height

      Operating System

      Microsoft Windows 7

      System Documentation

      Operator manual, quickstart guide, and context-sensitive online help

      Data Storage

      1,000,000 test/QC results; 500,000 can be historical; can archive to removable media

      Onboard Maintenance Logs

      Yes

      Host Interface

      RS232C bidirectional and host query; Ethernet connection available

      Host Query

      Yes

      Remote Access & Service

      1000Base-T Ethernet port for remote access and modem for Siemens Remote Service

      Removable Media

       

      Removable Media

      CD, DVD, or USB

      General Specifications

       

      Power Requirements

      200-240 V at 50/60 Hz; 1.2 kW maximum

      Maximum Water Consumption

      2.5 liters (0.6 gallons) per hour

      Drain Requirements

      Minimum of 2.5 liters (0.6 gallons) per hour

      Dimensions

      With monitor: 167 (h) x 196 (w) x 104 (d) cm; 66 (h) x 77 (w) x 41 (d) in.
      Without monitor: 133 (h) x 196 (w) x 104 (d) cm; 52 (h) x 77 (w) x 41 (d) in.

      Weight

      585 kg (1289 lb)

      Compliance

      Complies with international environmental, health, and safety standards

      Noise Emission

      65 dB maximum

      Processing Heat Output

      5100 BTU/hour

      Ambient Temperature

      18–30°C (64–86°F)

      Ambient Humidity

      20–80% noncondensing

      Floor Load-Bearing Requirement

      412 kg/m2 (84 lb/ft2)

      * Under development. Not available for sale.

      † Not available for sale in the U.S.

      ‡ CA 125II is a trademark of Fujirebio Diagnostics, Inc.

      § Assay developed, manufactured, and sold by Siemens Healthcare Diagnostics Inc. for Ortho Clinical Diagnostics, Inc. and Grifols Diagnostic Solutions Inc.

      ** Available in the U.S. only. Limited distribution.

      The outcomes achieved by the Siemens Healthineers customers described herein were achieved in each customer’s unique setting. Since there is no “typical” hospital and many variables exist (e.g., hospital size, case mix, level of IT adoption) there can be no guarantee that others will achieve the same results.

      The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.