N Latex BTP Assay
Rapid Detection of CSF leakage and Easier Estimation of RRF

N Latex BTP Assay
Kontaktujte nás

Fast and Accurate Detection of CSF Leakage
The new N Latex BTP Assay is the first fully-automated method to provide accurate, rapid, and cost-effective determination of CSF leakage with a simple, nephelometric lab test. Testing can be performed on minimal sample volumes of human serum, heparinized and EDTA-plasma, CSF, and nasal or ear secretions containing CSF. Results are comparable to the β2-transferrin immunofixation electrophoresis method, but faster, easier, and less expensive.

  • High specificity of 100% and sensitivity of 99% for accurate results.1
  • Performance is not subject to CDT interference.
  • 12 minutes to result—time to result from sample collection to final result possible in 1 hour—less than half the time needed B2Trf, enabling faster surgical intervention.1,2
  • Low incidence of false-positive results helps reduce costly imaging testing and possible loss of life due to misdiagnosis.

Simple and Precise Monitoring of RRF

Beta-trace protein (BTP) measurement with the N Latex BTP assay offers simpler sample retrieval and increased accuracy of RRF determination when compared to other methods. It is the first assay to accurately, reliably and simply estimate RRF status with one serum sample.

  • Only a single serum sample is needed for determination of BTP
  • Allows estimation of renal contribution to clearance - without inaccurate and cumbersome urine collection
  • Supports decisions regarding dialysis modality selection
  • Provides information clinicians need to adjust dialysis regimen as well as to anticipate and manage complications.


Share this page:

Related Products, Services & Resources

1Mantur M, Łukaszewicz-Zając M, Mroczko B, Kułakowska A, Ganslan dt O, Kemona H, Szmitkowski M, Drozdowski W, Zimmermann R, Kornhuber J, Lewczuk P. Cerebrospinal fluid leakage—reliable diagnostic methods. Clin Chim Acta. 2011 May

2Bachmann-Harildstad G. Diagnostic values of beta-2 transferrin and beta-trace protein as markers for cerebrospinal fluid fistula. Rhinology. 2008;46:82-5.

The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens organization for further details.