CK-MB mass

The Acute Care™ CK-MB assay is an in vitro diagnostic test for the measurement of the MB iso-enzyme of creatine kinase in heparinized whole blood/plasma. CK-MB measurements can be used as an aid in diagnosing acute myocardial infarction.

Clinical Significance
CK-MB is found primarily in cardiac tissue.1 CK-MB can be detected at elevated concentrations following myocardial damage. Abnormal plasma CK-MB concentrations are often associated with ischemia or necrotic heart injury. The increase in CK-MB concentration is often evident within 3 to 6 hours following onset of chest pain, reaching peak concentrations within 12 to 24 hours. CK-MB concentrations will generally return to normal within 24 to 72 hours.2 The determination of CK-MB is most beneficial when samples have been drawn at appropriate time intervals post onset of chest pain.


Delivering What Matters:

  • One sample, one run, one instrument; increases efficiency in triaging chest pain patients
  • Rapid turnaround time - in as little as 14 min. (with onboard centrifugation)
  • Single and ready to use TestPak™ Cartridges

     ° No reconstitution
     ° No warming to room temperature
     ° Reduction in reagent waste
     ° Reduction in contamination

  • Heparinized whole blood samples
  • Electronic QC (System Check) satisfies daily routine QC requirements permitting liquid QC flexibility 

For additional information on CK-MB mass visit our educational website at

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1Lang H, ed. Creatine kinase isoenzymes: pathophysiology and clinical application. Berlin: Springer-Verlag, 1981.

2Roberts R. Heart Lung 1981;10(3): 486-506.