BN ProSpec System

Uncompromising performance for plasma protein analysis

Product Tour

The BN ProSpec^® is a dedicated, compact system that offers a consolidated menu of specialty and routine reagents for reliable plasma protein testing including cardiac risk assessment, kidney diseases, nutritional assessment and iron and anemia assessment as well as innovative markers such as Cystatin C and Carbohydrate-Deficient Transferrin (CDT).

Ideal for low- to mid-volume plasma protein throughput
Comprehensive menu from one source: Over 64 assay protocols available for determination of various sample types
Optimal alignment of systems and reagents
Refrigerated onboard storage of controls and reagents

Features & Benefits

The BN ProSpec^® System uses our proven nephelometric technology for the determination of a large variety of assays which support the management of disease states such as iron and anemia assessment, gammopathies / immune system, kidney disease, and many others.

The BN ProSpec System is a fully automated benchtop analyzer which combines efficient workflow with cost-effective determinations for plasma protein testing needs:

Patient-oriented sample processing for efficient workflow
Convenient handling due to onboard storage of reagents and controls
Highly reliable patient results with optimized system components

The BN ProSpec provides you with:

Increased workflow efficiency

Average effective throughput of 65 tests/hour
Onboard capacity for up to 1.5 hour walkaway convenience
24-hour onboard refrigerated reagent storage to eliminate removal of controls and reagents
Enhanced onboard stability – generally up to 6 weeks for reagents and 1 week for controls
Barcode identification for primary sample tubes, standards, controls and reagents
Sample auto-dilution and configurable, automatic repeat measurements for fast results with less operator intervention
Secure interruption of assay runs for calibration and reloading – no loss of data
Specimen level-detection

Confidence in results

Optimal alignment of reagents and system
High reliability with antigen-excess security
Proven nephelometric technology

Comprehensive solutions

Broad menu available from one source: Over 64 assay protocols available for determination in various body fluids
Consolidation of specialty and routine parameters to support disease state management

Innovative assays:

CardioPhase^® hsCRP – a trendsetting assay acknowledged as independent marker of cardiovascular risk
Unique, fully automated Carbohydrate-Deficient Transferrin (%CDT) assay with the specificity of HPLC
Cystatin C – increasing sensitivity and reliability in renal function analysis
Active participation in protein method standardization projects

Assays

Polyclonal & Monoclonal Gammopathies / Immune System
IgG
IgG CSF
IgG subclasses 1-4
IgA
IgM
Ig/light chain, type kappa
Ig/light chain, type lambda
FLC kappa*
FLC lambda*
ß2-Microglobulin

Kidney Disease
Albumin urine
α1-Microglobulin urine
α2-Macroglobulin
β2-Microglobulin urine
Cystatin C (serum)
IgG urine
Ig/light chain, type kappa urine
Ig/light chain, type lambda urine
Transferrin urine

Inflammation
α1-Acid glycoprotein
CRP
Fibrinogen
SAA*

Autoimmune/Rheumatoid Diseases
ADNase B
ASL
CRP
RF
C3c
C4

Allergic Diseases
IgE

Nutritional Assessment
Albumin
Prealbumin
RBP (Retinol Binding Protein)
CRP
Ferritin

Coagulation Disorders
AT-III
Fibrinogen
Plasminogen

Anemia/Iron Metabolism
Ferritin
Haptoglobin
Hemopexin
sTfR (Soluble Transferrin Receptor)
Transferrin

Complement Activity
C1 Esterase Inhibitor
C3c
C4

Blood-Brain-Barrier Dysfunction
Albumin
Albumin CSF
IgG
IgG CSF
IgA
IgA CSF
IgM
IgM CSF

Other Specialty Analytes
a1-Antitrypsin
α2-Macroglobulin
Apo A-II*
Apo E*
Ceruloplasmin
Fibronectin*

Cardiovascular Risk / Acute Cardiac Care
High Sensitivity CRP (CardioPhase® hsCRP)
Fibrinogen
Apo A-I
Apo B
Homocysteine
Lp(a)
Myoglobin
Albumin urine
Cystatin C

Chronic Alcohol Abuse
CDT (Carbohydrate Deficient Transferrin)
Transferrin (for %CDT calculation)

Allergic Diseases
IgE

Nutritional Assessment
Albumin
Prealbumin
RBP (Retinol Binding Protein)
CRP
Ferritin

Coagulation Disorders
AT-III
Fibrinogen
Plasminogen

Anemia/Iron Metabolism
Ferritin
Haptoglobin
Hemopexin
sTfR (Soluble Transferrin Receptor)
Transferrin

Complement Activity
C1 Esterase Inhibitor
C3c
C4

Blood-Brain-Barrier Dysfunction
Albumin
Albumin CSF
IgG
IgG CSF
IgA
IgA CSF
IgM
IgM CSF

Other Specialty Analytes
a1-Antitrypsin
α2-Macroglobulin
Apo A-II*
Apo E*
Ceruloplasmin
Fibronectin*

Technical Specifications

Measuring principle	Nephelometry; measurement of the scattered light intensity in a fixed angle of 13 - 24 degrees
Methods	More than 60 programmed assay protocols
Sample throughput	Effective: Approx. 65 tests/hour depending on the assay mix Nominal: 100 tests/hour
Analysis method	Fixed-time kinetics, end-point measurement, VLin Integral
Calibration	Multi-point calibration
Rack transport unit	Segments for 3 control serum vials Segments for 2 reagent vials Segments for 15 sample tubes
Dilution unit	1 frame for max. 132 dilution cups
Size of sample tubes	Diameter: 11 - 16 mm Height: 55 - 100 mm For pediatric samples: conical microtubes with a maximum filling volume of 1.5 mL
Barcode types	Automatic reading of different barcode types: 2/5 interleaved Codabar Code 39 Code 93 Code 128
Reagent volume	40 µL reagent consumption on average
Sample dilution	1 : 1 to 1 : 32,000
Level detection	For samples, standards, controls, and reagents
Reaction cuvettes	90 disposable cuvettes
Measuring temperature	37 ± 1.5°C
Light source	Infrared high performance LED
Wavelength	840 ± 25 nm
Detector	Photodiode with integrated pre-amplifier
Instrument weight and dimensions	Analyzer dimensions (width x height x depth) 109.2 cm 81.3 cm x 63.5 cm (43 in. x 32 in. x 25 in.) Computer and monitor dimensions (width x height x depth incl. keyboard) 36.2 cm x 45.7 cm x 54.6 cm (14.25 in. x 18 in. x 21.5 in.) Printer dimensions (width x height x depth) 40.6 cm x 26.6 cm x 36.8 cm (16 in. x 10.5 in. x 14.5 in.) Weight Analyzer: 115,2 kg (254 lbs.) Computer: 5.9 kg (13 lbs.) Monitor: 12.6 kg (27.7 lbs.) Printer: 7.3 kg (16.1 lbs.)
Room environment	Ambient temperature 18 to 32 °C (64 to 89 °F) Relative humidity Maintain between 30% and 85% (noncondensing) Average thermal output 340 BTU/hr (100 W) in standby mode 975 BTU/hr (286 W) in operating mode Water requirements Deionized water NCClS Type 2 Microbial count must not exceed 100 CFU/ml
Electrical installation requirements	Voltage 117 to 127 V/50 or 60 Hz 207 to 253 V/50 or 60 Hz Power consumption <140 VA (standby mode) <400 VA (operating mode)
Host interfacing	Download mode, host-query mode, ASTM
Ports	1 Serial (DB-9) (male) 1 10-Base-T/Base TX Ethernet RJ45
Computer and Printer	Terminal Windows^® CP Printer Lexmark E260 D or DN or equivalent

Services & Support Education & Training

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The products/features shown on this webpage are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.

*Not available for sale in the U.S.