The ADVIA Centaur® XPT Immunoassay System is engineered for simplified, continuous operation and timely, trusted results.
"The ADVIA Centaur XPT System exceeded our expectations. Furthermore, we could reduce the monthly maintenance by 12 hours per year and operator maintenance time by 60%."
See how Labor Blackholm MVZ increased testing volume by 34% with 30% fewer analyzers
Anemia
Active B12
EPO
Ferritin
Folate
RBC Folate
Vitamin B12
Autoimmune
Anti-CCP IgG
Bone Metabolism
Intact PTH
Vitamin D Total
Cardiac
BNP
CKMB
High-Sensitivity Troponin I
Myoglobin
NT-proBNP
Diabetes
C-Peptide
Insulin
Hepatitis
Anti-HBe
Anti-HBs 2
HAV IgM
HAV Total
HBc IgM
HBc Total
HBc Total 2
HBeAg
HBsAg Confirmatory
HBsAg II
HBsAg II Quant
HCV
HIV
HIV 1/O/2 Enhanced (EHIV)
HIV Ag/Ab Combo (CHIV)
Immunosuppressant Drugs
Cyclosporine
Everolimus*
Sirolimus*
Tacrolimus*
Inflammation
IgE Total
IL-6
LBP
TNFα*
Liver Fibrosis
Enhanced Liver Fibrosis (ELF™) Test
HA (ELF™ Marker)
PIIINP (ELF™ Marker)
TIMP-1 (ELF™ Marker)
Metabolic
Cortisol
Homocysteine
Neurology
β-Amyloid 1-42 (AB42)*
Total Tau (TTAU)*
Oncology
AFP
BR 27.29
CA 125II†
CA 15-3†
CA 19-9†
Calcitonin
CEA
Complexed PSA
CYFRA 21-1*
Free PSA
Neuron Specific Enolase (NSE)*
PSA
Serum HER-2/neu
Squamous Cell Carcinoma Antigen (SCC)*
Reproductive Endocrinology
AFP
Androstenedione
Anti-Müllerian Hormone*
DHEA-SO4
Enhanced Estradiol
Free Beta HCG
FSH
hCG
LH
PAPP-A
PlGF*
Progesterone
Prolactin
sFLT-1*
SHBG
Testosterone II
Sepsis
Procalcitonin (PCT)
Special ID
EBV-EBNA IgG*
EBV-VCA IgG*
EBV-VCA IgM*
SARS-CoV-2 Ag (CoVAg)**
SARS-CoV-2 IgG (COV2G)§
SARS-CoV-2 IgG (sCOVG)**
SARS-CoV-2 Total (COV2T)§
Syphilis
Zika Test‡
Therapeutic Drug Monitoring (TDM)
Carbamazepine
Digitoxin
Digoxin
Gentamicin
Phenobarbital
Phenytoin
Theophylline
Valproic Acid
Vancomycin
Thyroid
aTgII
Anti-TPO
Free T3
Free T4
Total T3
Total T4
TSH3-Ultra
TSH
T Uptake
ToRCH
CMV IgG
CMV IgM*
Herpes-1 IgG
Herpes-2 IgG
Rubella IgG II
Rubella IgM
Toxoplasma IgG
Toxoplasma IgM
Product Specifications |
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System Description | Random-access immunoassay system |
Test Throughput | Up to 240 tests per hour |
Time to First Result | 18 minutes; results every 15 seconds thereafter, assay dependent |
Assays Onboard | 30 assays |
Disease-State Assay Groups§§ | Allergy, Anemia/Iron Metabolism, Bone Metabolism, Cardiac, Diabetes, Hepatitis, HIV, Immunosuppressant Drugs, Liver Fibrosis†, Metabolic, Oncology, Reproductive Endocrinology, Sepsis†, Special ID, Therapeutic Drug Monitoring (TDM), Thyroid, ToRCH |
Continuous Operation | Loading/unloading of samples and consumables at any time without interrupting system operation. Includes sample racks, STATs, reagent packs, ancillary reagent packs, reaction cuvettes, sample pipette tips, calibrators, controls, wash fluids, water, and waste. |
Sample Handling |
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Sample Tubes | 3 mL, 5 mL, 7 mL, and 10 mL tubes; 1 mL and 2 mL sample cups; microcontainer tubes |
Sample Input | Universal 5-position rack holds multiple tube types; 180 samples fully loaded; no-pause loading and unloading |
Validated Sample Types | Serum, plasma, urine (assay-dependent) |
Sample Volume per Test | 10–200 μL, assay-dependent |
Sample Integrity Control | Pressure transducer technology with clot detection, flagging, and management; short-sample detection |
STAT Handling | Dedicated STAT port accepts samples any time; STAT samples are processed with priority |
Auto-repeat | User-definable |
Sample Dilution | Automatic dilution varies by assay, up to 1:2500 |
Auto-reflex Testing | Automatic ability to perform additional tests based on results of first test |
Sample Pipette Tips | 840 disposable sample tip capacity |
Sample Carryover Prevention | Disposable pipette tips ensure zero sample carryover |
Bar Codes |
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Sample Bar Codes | Up to 20 digits; Interleaved 2 of 5; Code 39, Code 128, Codabar; A, B, and special characters (.-+/*$%) |
Reaction Area |
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Reaction Cuvettes | Capacity of 1000 optical-grade plastic cuvettes |
Reaction Bath | Air bath, 37°C |
Assay Result Calculations | SMART algorithm software repeats and confirms reactive testing; results available as completed |
Assay Technology | Chemiluminescence using Advanced Acridinium Ester |
Reagent Handling |
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Reagent Tray | 30-position reagent tray refrigerated between 4 and 10°C (39–50°F) |
Reagent Capacity Onboard | 30 assays |
Reagent Containers | ADVIA Centaur® ReadyPack® (various pack sizes available) |
Reagent Integrity Control | Bar-code reagent identification, automatic inventory tracking and flagging, calibration valid tracking and flagging, reagent onboard stability tracking and flagging, reagent expired/reagent low flagging |
Onboard Stability | 28 days (average) |
Reagent Mixing | ADVIA Centaur ReadyPacks automatically rocked onboard |
Ancillary Reagents | 25-position ancillary reagent tray cooled 4–8°C (39–46°F) |
Calibration/QC |
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Auto-calibration/Auto-QC | Available automatic QC ordering by test, control, date, and time |
QC Data | Advanced QC package includes Levey-Jennings plots and Westgard rules |
User Interface/Data Management |
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Monitor | 22-inch diagonal high-resolution LCD touchscreen with adjustable height |
Operating System | Microsoft Windows 7 |
System Documentation | Operator manual, quickstart guide, and context-sensitive online help |
Data Storage | 1,000,000 test/QC results; 500,000 can be historical; can archive to removable media |
Onboard Maintenance Logs | Yes |
Host Interface | RS232C bidirectional and host query; Ethernet connection available |
Host Query | Yes |
Remote Access & Service | 1000Base-T Ethernet port for remote access and modem for Siemens Remote Service |
Removable Media |
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Removable Media | CD, DVD, or USB |
General Specifications |
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Power Requirements | 200-240 V at 50/60 Hz; 1.2 kW maximum |
Maximum Water Consumption | 2.5 liters (0.6 gallons) per hour |
Drain Requirements | Minimum of 2.5 liters (0.6 gallons) per hour |
Dimensions | With monitor: 167 (h) x 196 (w) x 104 (d) cm; 66 (h) x 77 (w) x 41 (d) in. |
Weight | 585 kg (1289 lb) |
Compliance | Complies with international environmental, health, and safety standards |
Noise Emission | 65 dB maximum |
Processing Heat Output | 5100 BTU/hour |
Ambient Temperature | 18–30°C (64–86°F) |
Ambient Humidity | 20–80% noncondensing |
Floor Load-Bearing Requirement | 412 kg/m2 (84 lb/ft2) |
* Under development. Not available for sale.
† CA 125II , CA 19-9 and CA 15-3 are trademarks of Fujirebio Diagnostics, Inc.
‡ Limited distribution
§ This test has not been FDA cleared or approved. This test has been authorized by FDA under an EUA for use by authorized laboratories. This test has been authorized only for detecting the presence of antibodies against SARS-CoV-2, not for any other viruses or pathogens. This test is only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of in vitro diagnostics for detection and/or diagnosis of COVID-19 under Section 564(b)(1) of the Act, 21 U.S.C. § 360bbb-3(b)(1), unless the authorization is terminated or revoked sooner. Product availability may vary by country.
** This test has not been reviewed by the FDA. In the US, use of this test is limited to laboratories that are certified under Clinical Laboratory Improvement Amendments of 1988 (CLIA) to perform high-complexity testing. Product availability may vary by country and is subject to regulatory requirements.
The outcomes achieved by the Siemens Healthineers customers described herein were achieved in each customer’s unique setting. Since there is no “typical” hospital and many variables exist (e.g., hospital size, case mix, level of ITadoption) there can be no guarantee that others will achieve the same results.
The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.
