The ADVIA® Chemistry XPT System provides timely, reliable results with continuous operation to meet the chemistry workloads of the most demanding laboratories.
- Delivers high throughput of up to 2400 tests per hour.
- Manages comprehensive testing with a menu of more than 115 assays.
- Improves workflow using automation and system technologies such as micro-volume and aliquot retention.
ADVIA Chemistry XPT System
Features & Benefits
The ADVIA® Chemistry XPT System*** is engineered for continuous operation and timely, accurate results—supporting you to reach your full potential today and be prepared for tomorrow. With an advanced user interface that is easy to use and VeriSmart® Technology to support accuracy of testing, the ADVIA Chemistry XPT System predictably and consistently delivers timely, reliable results to meet expanding workloads.
- Simplify operation and training with the intuitive, icon-driven user interface.
- Extend walkaway times with concentrated reagents that provide high test capacity onboard.
- Quickly load most system fluids on the fly.
- Automate calibration, QC, startup, and shutdown.
Consistent, Predictable Turnaround Time and Accuracy
- Offer a comprehensive chemistry menu of over 115 assays, including general and specialty chemistry, DAT, TDM, and specific proteins.
- Push productivity with a throughput of up to 2400 tests per hour (1800 photometric, plus 600 ISE).
- Control testing: STAT and specialty samples can always be front-loaded while an automation track is running.
“Significantly, the system has demonstrated a turnaround time (TAT) at peak workload times almost as good as that of three chemistry systems. This proves that less equipment is needed to perform the same workload and achieve the same TAT.”
Designed for Automation
- Adapt and grow with direct connectivity to Siemens Aptio® Automation and ADVIA® Automation Solutions.
- Simplify your laboratory operations with connectivity to IT solutions including CentraLink® Data Management System, Atellica™ PM Software, and Siemens Remote Service (SRS).
- Increase productivity and efficiency with direct-from-track sampling and onboard aliquoting that allows samples to be immediately released to the next workstation.
"So far, the workload achievements resulted in 45 percent faster turnaround time for clinical chemistry testing."
Do More with Less
- Reduce blood-draw requirements with micro-volume technology that uses a single 30 μL sample for up to 15 tests.
- Eliminate sample callback with automated, pre-programmable dilution, reflex, and rerun testing that uses an onboard aliquot.
- Improve workflow and accuracy with VeriSmart® technologies that perform hardware and software checks at all stages of sample processing.
Hemoglobin A1c (Enzymatic)
Drugs of Abuse/Toxicology
Ethyl Glucuronide (EtG)††,§§
Alanine Aminotransferase (P5P)†
Alkaline Phosphatase (AMP)
Aspartate Aminotransferase (P5P)†
Carbon Dioxide (Enzymatic)
Lactate Dehydrogenase (L-P)
Lactate Dehydrogenase (P-L)
Total Iron Binding Capacity (TIBC)
Total Protein, CSF/Urine
Urea Nitrogen (BUN)†
CRP, High Sensitivity
CRP, Wide Range
Soluble Transferrin Receptor (sTfR)§,††
Therapeutic Drug Monitoring
Fully random and continuous access, discrete processing clinical chemistry system with batch run capability
Up to 2400 tests/hour: 1800 tests/hour photometric, 600 tests/hour ISE
59 assays, including 3 ISE (Na, K, Cl)
5 mL, 7 mL, and 10 mL tubes; 1 mL and 2 mL sample cups; user-defined containers
84 sample positions; positive sample identification
Validated Sample Types
Serum, plasma, urine, whole blood, and CSF, assay-dependent
Sample Integrity Control
Qualitative check for hemolysis, lipemia, and icterus; clot detection, flagging, and management; short-sample detection, flagging, and management
84 positions, not dedicated; STAT samples are processed with priority
Automatic repeat testing from the retained prediluted sample or original sample
Automatic dilution up to 1:5625 from retained prediluted sample or original sample
Automatic ability to perform additional tests based on results of first test or test combination
Primary Sample Probe
Liquid-level sensing, crash protection, clot/clog detection, liquid-surface verification
Sample Carryover Prevention
Automated wash; additional automated sample probe washes programmable for greater prevention
Up to 200 tubes per hour with ISE use; faster without ISE use
Sample Bar Codes
Up to 20 digits; Interleaved 2 of 5, Code 39, Code 128, Codabar; A, B, and special characters (.-+/*$%)
Automatic Sample Predilution
Samples typically diluted 1:5 (30 μL sample + 120 μL saline generates up to 15 tests results); retained for auto-repeat, auto-reflex, or auto-dilution until results are available
120 dilution cuvettes
Sample Volume per Test
2–30 μL of prediluted sample, equating to 0.4–6.0 μL of original sample per test (varies by assay)
Average Reagent Volume
80–120 μL per test, assay-dependent
340 reusable optical-grade plastic cuvettes
Inert fluorocarbon oil circulation system, 37°C
14 fixed wavelengths (340, 410, 451, 478, 505, 545, 571, 596, 658, 694, 751, 805, 845, and 884 nm)
12V, 50W halogen lamp, cooled by forced water circulation
Assay Result Calculations
Endpoint (EPA), rate reaction (RRA), 2-point rate (2PA), constant rate analysis (CRA), and immunoassay analysis (IMA) methodologies; prozone checking; substrate depletion check; results available as completed
3, 4, 5, and 10 minutes; extended reaction times 15 and 21 minutes
Sample blank, cuvette blank, measurement point change, sample volume change in re-assay
Can automatically extend linearity to measure samples over assay range
Potentiometric, photometric, turbidimetric
2 trays, (R1=60 and R2 =56 positions), refrigerated between 6°C and 13°C (43°F–55°F)
Reagent Capacity Onboard
56 photometric assays
Test Capacity Onboard
40,000 photometric tests average; over 100,000 photometric tests with the use of concentrated reagents
20, 40, 70 mL reagent wedges
Reagent Integrity Control
Bar-code reagent identification; automatic inventory tracking and flagging; calibration and control validity tracking and flagging; reagent onboard stability tracking and flagging; reagent expired/reagent low flagging
Up to 60 days, depending on assay
Capability to dilute concentrated reagents onboard
200 assay channels; includes 50 channels for user-defined applications
Ion-selective Electrodes (ISE)
Indirect simultaneous measurement of Na+, K+, Cl-
ISE Sample Volume
22 μL original sample for all three tests
Electrode Expected Use Life
30,000 samples or 3 months, whichever occurs first
Up to 600 tests/hour; 200 tubes/hour
Validated Calibration Interval
Up to 60 days, tracked by software
User-defined time interval or with new reagent container
User-defined test count interval or with auto-calibration
Graphical display of calibration curves
Graphical display of QC; real-time/QC monitoring; Advanced QC package includes Levey-Jennings plots, Westgard rules, and RiliBÄK rules; 125,000 control results can be stored, archivable to removable media
61 refrigerated positions for calibrators, controls, and diluents
User Interface/Data Management
22-inch (55.9 cm) diagonal high-resolution LCD touchscreen with adjustable height
Microsoft® Windows® 7
Operator manual, quickstart guide, and online help
500,000 active plus 500,000 historical test results; can archive to removable media
Onboard Maintenance Logs
ASTM; system requests work order or batch of work orders from host
Remote Access and Service
Siemens Remote Service via 1000BASE-T Ethernet port
DVD, CD-RW, or USB
200–240V at 50/60 Hz, 3 kVA consumption
CLSI® Clinical Laboratory Reagent Water or equivalent connected directly to a pressurized water source
Maximum Water Consumption
40 liters (10.6 gallons) per hour
Minimum of 40 liters (10.6 gallons) per hour
With monitor: 149 (h) x 177 (w) x 99 (d) cm; 59 (h) x 70 (w) x 39 (d) inches
725 kg (1598 lb)
Complies with international environmental, health, and safety standards, including CE and RoHS
Less than 62 dB
Processing Heat Output
* Alliance Application manufactured and distributed by Siemens Healthcare Diagnostics.
† Also available in concentrated version.
‡ ADVIA Chemistry XPT System supports concentrated version only.
§ Not available for sale in the U.S.
** Not currently available on the ADVIA Chemistry XPT System.
†† Alliance Application manufactured by third party, distributed by Siemens Healthcare Diagnostics.
‡‡ In development, future availability cannot be guaranteed.
§§ Restricted in the U.S. to law enforcement-related use (forensic use only).
*** Due to local regulations, not all products are available in all countries.
The products/features (mentioned herein) are not commercially available in all countries. Due to regulatory reasons their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details.
Product availability may vary from country to country and is subject to varying regulatory requirements. Please contact your local representative for availability.
The outcomes achieved by the Siemens Healthineers customers described herein were achieved in each customer’s unique setting. Since there is no “typical” hospital and many variables exist (e.g., hospital size, case mix, level of IT adoption) there can be no guarantee that others will achieve the same results.