syngo.via Frontier
Bridge the gap in post-processing translational research

syngo.via Frontier
syngo.via Frontier

With syngo.via Frontier1, you can explore the potential of advanced post-processing prototypes that are seamlessly integrated with your routine syngo.via system. syngo.via Frontier also enables you to easily implement your own algorithms and connects you directly with other key opinion leaders and the Siemens Healthineers development teams2.

Características y Beneficios

Explore the unseen

syngo.via Frontier allows you to strengthen your clinical opinion leadership with an easy access to numerous post-processing prototypes that are seamlessly integrated with your routine syngo.via environment. The dedicated syngo.via Frontier Prototype Store is continuously enriched with new contributions.

  • Access from any syngo.via client
  • One workplace and a similar user interface for research and clinical tasks
  • Easy data transfer to and from the local syngo.via environment
  • Upload of prototypes on the syngo.via Frontier server3


Create innovation 

The syngo.via Frontier Development Kit provides you with an integrated solution to translate clinical requirements into programming language. This enables you to rapidly transform your clinical ideas into tangible prototypes. To get started efficiently, you can use the Prototype Starter Kit that enables you to easily reuse existing code for your own prototype development.

  • Close cooperation between physicists or programmers and clinicians via a common platform
  • Quick and easy prototype development with predefined modules and clinical libraries
  • Prototyping can be done at different levels: from interactive network level to MeVis MDL, Python, and C++
  • Easy integration of your own existing algorithms
  • Faster algorithm iterations for smoother clinical validation

syngo.via Frontier opens up the possibility to use the development kit of your choice.

  • Integration of portable applications
  • Integrate your own “.exe” prototypes
  • Use a simple interface for your existing prototype
  • Easier productization of prototypes with different developer environments (3D Slicer, CT iPipe, C++, C#, itk/vtk, …)

Join the pioneer community 

By joining the syngo.via Frontier Forum you become part of an exclusive global network of clinicians and researchers – an ideal platform to share your ideas in prototype development and bring your research activities closer to a trusted industry partner.

  • Fruitful interaction with other institutions and key opinion leaders
  • Global visibility for research activities
  • Possibilities to test and validate new developments on a large scale, up to a multi-center approach
  • Direct access to Siemens Healthineers R&D
  • Easier validation of prototypes

Uso de Búsqueda

Examples of prototypes:
The syngo.via Frontier Prototype Store is continuously enriched with new contributions from Siemens Healthineers R&D and external partners. Here are some current examples for different modalities.

CT prototypes1

Skull and Pelvis Unfolding
This prototype enables a fully-automatic unfolding of skull and pelvis that aids in the detection of fractures and bleeding:

  • Unfolding of pelvic bone, skull base, skull vault and the soft tissue directly beneath the vault
  • Improved sensitivity in detection of fractures and hematoma – fast and easy4,5
  • Synchronized navigation between unfolding views and MPRs 

Coronary Plaque Analysis
This prototype allows volumetric quantification and differentiation of lipid, fibrous, and calcified plaques.

  • Advanced tools for analyzing atherosclerotic plaque morphology and characterizing different plaque composites, such as lipid and fibrous
  • Overall Plaque Burden
  • Segment Involvement Score
  • Quantitative Remodeling Index
  • Quantitative Eccentricity Index
  • Potential to assess the vulnerability of atherosclerotic lesions and evaluate strategies for stabilizing plaque


DE Rho/Z Maps
This advanced Dual Energy technique provides tissue differentiation based on electron density and effective atomic number.

  • Improved differentiation and characterization of different tissues
  • Allows the conversion of standard Hounsfield units into electron density maps without the use of calibration phantoms that may lead to deviations
  • More reliable planning for radiation therapy and reduced risk of overexposure


DE Scatter Plots
This research prototype provides a novel representation of Dual Energy information: The energy dependencies of materials shown within a region of interest (ROI) are visualized graphically.

  • Complete statistical evaluation of an ROI
  • Visualization of energy dependencies for analyzing material homogeneity
  • Detailed material analysis with advanced statistical parameters such as variance and skewness



  • This prototype allows to generate Iron/VNC images from Dual Energy acquisition and potentially evaluate hemochromatosis.
  • Calculates VNC/CA – images
  • Create ROI's to inspect visualized data
  • Calculates iron content in ROI
  • Change opacity of image layers
  • Images are exportable


Flow Visualization
Whereas perfusion techniques evaluate the patient’s brain parenchyma, the main goal of this prototype is to provide insight on the dynamics of the vascular structures.

  • Complementary visualization of dynamic data
  • Overlay of the color image to the tMIP (temporal Maximum Intensity Projection) of the perfusion dataset, showing the time of maximal enhancement
  • Visualization of the blood flow from the arteries to the sinus sagitalis superior in colors corresponding to the time over the MPRs or VRT


Cardiac Functional Analysis
This prototype compiles a functional analysis of the heart and its compartments from different CT acquisitions and datasets.

  • Incorporates stress and rest studies, static and dynamic myocardial perfusion, multiphase CTA, Dual Energy Perfused Blood Volume, and others
  • Quantitative statistical analysis of 2D polar map-related AHA segments and user-defined ROIs in the underlying 3D data
  • Automatic segmentation of left ventricle (epi- and endocardium), right ventricle, and left and right atria


Best Contrast
Best Contrast employs multiband filtering to improve low-contrast resolution while keeping noise unaffected.

  • Improved contrast-to-noise ratio
  • Enhanced image quality and tissue differentiation
  • Potential to reduce radiation dose


Cardiac Risk Assessment
This prototype uses non-contrast CT data to provide an analysis of visceral fat.

  • Quantitative abdominal and pericardial fat analysis
  • Includes fat volumes, histograms, and other measurements such as the waistline or patient diameters
  • Improved risk assessment for cardiovascular disease and type 2 diabetes


Bone Subtraction
This software allows the identification of bone lesion progression from baseline to follow-up study.

  • Improved identification of subtle changes in bone lesions, such as hyperplasia and bone metastasis
  • Intelligent and adaptive image subtraction for spine and pelvis
  • Includes quantitative analysis tools to statistically calculate the bone density loss/gain
  • Intelligent synchronization and navigation between baseline and follow-up scans


MR prototypes

Track Density Imaging (TDI)
Track Density Imaging aids the visualization of brain structures, such as the different thalamic nuclei. This could potentially help facilitate neurosurgery research6

  • syngo.via Frontier TDI prototype generates tract density images with multiple user-specifiable options
  • Grey-scale and colored images are displayed as MPR together with the unformatted original
  • Images (grey-scale and colored) can be exported in DICOM format


Quantitative Analyzer

  • Designed to generate multiple MR contrasts using quantitative T1 and T21 maps, M01 data, and optional ADC map.
  • Contains preset contrasts (DIR, FLAIR, PSIR, …)
  • User-specific contrasts can be generated with interactive sliders (TR, TE, TI1, TI2, b-value) and ROI-based tissue nulling. Contrast presets can be saved for future use
  • ROI-based statistical analysis and DICOM/CSV export


Orthopedic Radial MPR
Designed to help the user efficiently create radial MPRs of 3D hip and knee images acquired with AutoAlign

  • Planned update: allow 3D PD FS hip images without AutoAlign as input
  • Automatic positioning and orientation of radial MPRs for hip and knee images
  • Single-click toggle between left and right hip joints
  • Angle measurement tool
  • Images can be exported as DICOM, measurements as CSV


Body Diffusion
Provides three state-of-the-art parametric models for DWI

  • Monoexponential model
  • Intravoxel Incoherent Motion (IVIM): bi-exponential model based on very low b-values 2
  • Diffusion Kurtosis Imaging (DKI): Parabolic model based on very high b-values


  • Pixel-based evaluation of the fit and measured curves
  • Computed b-value image using any of the models
  • ROI measurements

DICOM export


MR Total Tumor Load

  • Designed for fast quantitative assessment of whole-body diffusion-weighted exams (WB DWI)
  • Automatic composing of axial DWI series and automatic MIP
  • Interactive calculation of computed b-value images with normalization tool for follow-up
  • Interactive threshold-based volumetric segmentation with manual editing tools
  • Volumetric ADC histogram, back-mapping, statistical analysis
  • DICOM, CSV export


CT/MR prototypes1

Cinematic Rendering
Cinematic Rendering is a unique rendering technology based on a physically accurate simulation of how light interacts with matter. It provides a photo-realistic rendering of:

  • Shapes
  • Shadows
  • Scattering and subsurface scattering

Cinematic rendering is designed to see in vivo the true anatomy for improved counseling, surgery planning, teaching, and other purposes.

Ranges can be generated and exported in DICOM format.

3D Printing
Enables the segmentation of individual anatomical structures from CT or MR datasets to generate STL files for 3D printers.

Multiple segmentation tools, e.g.:

  • Volumetric tools like region growing and HU-based thresholding
  • Semi-automatic contouring tools using smart interpolation
  • Object editing tools
  • Support for hollow model creation

Import of segmentation objects generated in other syngo.via or research applications


Productos, servicios y recursos relacionados

1For research use only. Not for clinical use.

2Requires specific agreement with Siemens Healthineers

3Requires syngo.via Frontier Development Kit

4Ringl H., Schernthaner R. E., Schueller G., Balassy C. et. al.: „The skull unfolded: a cranial CT visualization algorithm for fast and easy detection of skull fractures.“ Radiology, 255(2), May 2010, 553-562.

5Ringl H., Stiassny F., Schima W., Toepker M., Czerny C., Schueller G. et. al.: „Intracranial hematomas at a glance: advanced visualization for fast and easy detection.“ Radiology, 267(2), May 2013, 553-562.

6Shepherd TM, Chung S, Glielmi C, Mogilner AY, Boada F, Kondziolka D. 3-Tesla magnetic resonance imaging track density imaging to identify thalamic nuclei for functional neurosurgery. Paper presented at: CNS 2014. Proceedings of the 63rd Annual Congress of Neurological Surgeons; 2014 Oct 18-22; Boston, USA.