ELF™ Test Now available!
ELF*: The first CE marked Liver Fibrosis Marker Panel

The ELF test is a simple, accurate, minimally-invasive blood test for measuring liver damage (known as fibrosis). It offers a quick straightforward method of providing valuable information:

 

  • Minimal or no patient discomfort
  • Identifies significant liver disease

 

Because ELF uses a blood sample rather than a biopsy, it can be used routinely for the same patient over time.

The ELF test - Three serum biomarkers

The ELF test combines three serum biomarkers which have been shown to correlate to the level of liver fibrosis assessed by liver biopsy. These biomarkers include:

 

  • Hyaluronic acid (HA)
  • Procollagen III amino terminal peptide (PIIINP)
  • Tissue inhibitor of metalloproteinase 1 (TIMP-1)

 

The algorithm measures each of these markers by immunoassay, to create an ELF score. Sampling for the ELF test can be performed in a physician’s office or health center.

  

Download ELF specification sheet 0.4 MB
 

Education Information

What is liver fibrosis?

Non-invasive markers of liver fibrosis

The ELF Program
 

External Links

*The ELF test is only available outside the US

 

"The discovery of the ELF markers represents a significant advance in the diagnosis of patients with liver disease. Of particular benefit, the ELF test can help diagnose patients with mild-to-moderate liver fibrosis, which is usually asymptomatic, so that clinicians are able to intervene before significant damage to the liver occurs."


William Rosenberg, MD
Centre for Hepatology
University College London


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