Cascadas de Hemostasia Interactivas

The process of hemostasis protects and maintains the balance between blood loss and thrombotic events.
The major contributors are platelets, von Willebrand factor, and coagulation factors. Platelet dysfunction, von Willebrand disease, hemophilia, and anti-coagulant therapy represent the most common causes for excessive bleeding, while other disorders are associated with the risk of thrombosis. The balance between bleeding and thrombosis is ensured by a complex cascade which can be divided in three interacting processes: primary hemostasis, secondary hemostasis (coagulation), and fibrinolysis.

Primary Hemostasis Cascade

View the interactions between collagen, platelets, von Willebrand factor, and fibrinogen as they work together to form a platelet clot and prevent further blood loss following an injury.

Full Hemostasis Cascade Overview

View the complex process of how primary hemostasis, coagulation, and fibrinolysis work together to protect and maintain the balance between blood loss and thrombotic events.

Anticoagulant Cascade

View the interactive process of traditional and novel anticoagulant substances, including interactions with unfractionated heparin, vitamin K inhibitors, and direct oral anticoagulants.

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