BEP III SystemConfidence in reliability

The BEP® III System* with Enzygnost® and Novagnost® assays (ELISA) help to detect infectious diseases (IDD), such as HIV, hepatitis, borreliosis and herpes but also bacteria, fungi, worms and other parasites. It provides automated processing of microtitration plates (MTP) and complete in-process documentation. BEP III, Enzygnost and Novagnost offer:

  • Performance that improves lab efficiency
  • Flexibility to enhance laboratory organization
  • Safety and reliability
  • Integrated quality management
  • Broad menu of proven Enzygnost and Novagnost assays

Características e Benefícios

The BEP® III System and the Enzygnost® and Novagnost® reagents build the proven and reliable solution for specialty infectious disease testing, including retrovirus (HIV), hepatitis, bacteria, fungi, parasites, worms and the complete range for ToRCH.

Infectious Disease Testing

The BEP III System is known as an extremely reliable system for automated microtitration plates (MTP) processing: From incubation and washing through reagent pipetting and result evaluation.

The BEP III System ensures a high level of safety with reagent identification, continuous monitoring of individual components inside the system and enhanced documentation of individual processing steps.

It can be connected to the Quadriga BeFree® System to manage really high volume, ideal for blood banks and blood donor screening.

Find more features and benefits of the combination of Novagnost, Enzygnost and the BEP III System:

Performance that improves lab efficiency

  • Runs ELISA tests fully automated (including incubation, reagent dispensing, washing and photometric reading including automated validation and evaluation)
  • Achieves a high throughput with up to 10 MTPs in parallel
  • Loads MTPs continously
  • Allows to load up to 20 different reagents
  • Reduces manual steps and operator intervention
  • Pipettes reagents from original bottles
  • Monitors reagent volumes

Flexibility to enhance laboratory organization

  • Standardized interface to sample pipetting systems
  • Networking capability to LIS System
  • Easy adaptation to specific needs: traceability of important operation steps

Safety and reliability

  • Initialization self-check
  • Standardized and automated validation of system components
  • Barcode system for reagents and plates
    • Integrated barcode reader for strip identification
    • Identification of assay and reagent lot number
  • Reagents and microtiter plates identification
  • Automated level detection and monitoring of all reagent and system liquids

Integrated quality management

  • Delivers accurate and reliable results
    • Positive reagent identification
    • Disposable tips to eliminate carryover
  • Meets safety standards and GLP requirements
    • In-process control and documentation of individual processing steps
    • Integrated QC for the monitoring of positive and negative controls
    • Automated validation procedure to check key functions
  • Provides flexible and clear documentation:
    • Positive process reports, validation records
    • Service and maintenance log
    • Documentation of validation
  • Easy to use
    • Graphical intuitive user-interface


Enzygnost® Assays

Virus - Retrovirus
HIV Integral 4

Virus - Hepatitis
HBsAg 6.0
HBsAg Confirmatory Test
Anti-HBc monoclonal
Anti-HBs II
Anti-HCV 4.0
HBe/Anti-HBe monoclonal

Lyme link VlsE/IgG
Anti-Helicobacter pylori/IgG
Anti-Helicobacter pylori/IgA

Anti-Rubella Virus/IgG
Anti-Rubella Virus/IgM
Anti-CMV/IgG + IgM

Virus - Others
Anti-Measles Virus/IgG
Anti-Measles Virus/IgM
Anti-Parotitis Virus/IgG
Anti-Parotitis Virus/IgM
Anti-TBE/FSME Virus (IgG, IgM)

CSF Application for:
Enzygnost Anti-Measles Virus/IgG
Enzygnost Anti-Rubella Virus/IgG
Enzygnost Anti-VZV/IgG
Enzygnost Anti-HSV/IgG
Enzygnost Anti-Parotitis Virus/IgG
Enzygnost Lyme link VlsE/IgG
Enzygnost Borreliosis/IgM

Novagnost® Assays

Bordetella pertussis IgG
Bordetella pertussis IgM
Bordetella pertussis IgA
Bordetella pertussis Toxin IgG
Bordetella pertussis Toxin IgA
Brucella IgG
Brucella IgM
Chlamydia trachomatis IgA
Chlamydia pneumoniae IgA
Chlamydia trachomatis IgG
Chlamydia pneumoniae IgG
Chlamydia trachomatis IgM
Chlamydia pneumoniae IgM
Coxiella burnetii (Q-Fever) Phase 1 IgG
Coxiella burnetii (Q-Fever) Phase 2 IgG
Coxiella burnetii (Q-Fever) Phase 2 IgM
Diphtheria Toxin IgG
Diptheria Toxin 5S IgG
Legionella pneumophila IgG
Legionella pneumophila IgM
Leptospira IgG
Leptospira IgM
Mycoplasma pneumoniae IgG
Mycoplasma pneumoniae IgM
Mycoplasma pneumoniae IgA
Tetanus Toxin IgG
Tetanus Toxin 5s IgG

Herpes simplex Virus 1 IgG
Herpes simplex Virus 1 IgM
Herpes simplex Virus 2 IgG
Herpes simplex Virus 2 IgM
Herpes simplex Virus 1+2 IgG
Herpes simplex Virus 1+2 IgM

Virus - Others
Adenovirus IgG
Adenovirus IgM
Chikungunya IgG
Chikungunya IgM
Dengue IgG
Dengue IgM
Influenza A IgG
Influenza A IgA
Influenza B IgG
Influenza B IgA
Parainfluenza 1-3 IgA
Parainfluenza 1-3 IgG
Parvovirus B 19 IgG
Parvovirus B 19 IgM

Aspergillus fumigatus IgG
Aspergillus fumigatus IgM
Candida albicans IgG
Candida albicans IgM
Candida albicans IgA

Chagas IgG
Echinococcus IgG
Entamoeba histolytica IgG
Leishmania infantum IgG
Schistosoma mansoni IgG

Ascaris lumbricoides IgG
Toxocara canis IgG
Trichinella spiralis IgG
Taenia solium IgG

Especificações Técnicas


Operating voltage

100 - 240 V, AC (50 / 60 Hz)

Primary fuse

230 V/ 5 A slow-blow

Power consumption

450 VA (depending on operating mode)

Dimensions (W x D x H)

1,160 mm x 600 mm x 590 mm


94 kg

Incubation unit

Storage capacity and temperatures of incubation unit

10 microtitration plates at 37 °C

10 microtitration plates at room temperature

1 plate at 50 °C in the heating oven

Dispensing unit

No. of reagents

Up to 20 bottles of 15 ml or max. 10 bottles of 100 ml

25 – 300 µl in 1 µl increments per well

CV ≤ 2.0% for V ≥ 100 µl per well


Measurement principle

Mono- and bichromatic


Halogen bulb

Spectral range

340 – 650 nm

No. of interference filters


Half-value width

5 – 10 nm


340 nm, 405 nm, 450 nm, 492 nm, 570 nm, 620 nm, 650 nm

Absorbance linear measuring range

O ≤ A ≤ 2.7 at 405 – 650 nm

O ≤ A ≤ 2.0 at 340 nm



Consumption depends on the tests selected and on the plate throughput. A 10-plate test run uses on average 3 liters of washing solution. This results in a comparable volume of liquid waste.

Supply Unit

Operating voltage

110 V: 90 – 125 V (50 / 60 Hz)

230 V: 205 – 245 V (50 / 60 Hz)

Power consumption

200 VA

Dimensions (W x D x H)

350 mm x 600 mm x 250 mm


18 kg



The energy consumption of the computer and its operating data depend on the type of computer used. Please refer to your computer user guide if accurate information is required.


Up to 20 kg, depending on the model